Intravenous Tenecteplase Compared With Alteplase for Acute Ischemic Stroke in Canada (AcT): Bridging the Gap From Academia to Regulatory Approval | Stroke: Vascular and Interventional Neurology
BACKGROUNDIn the AcT (Alteplase compared to Tenecteplase) trial, tenecteplase (0.25 mg/kg) was non‐inferior to alteplase (0.9 mg/kg) for efficacy, and similar in terms of safety in patients with ac…