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    Shorter Time to Transcatheter Aortic Valve Implantation Is Associated With Improved Outcomes in Acute Decompensated Aortic Stenosis | Circulation: Cardiovascular Interventions - 1 month(s) ago

    BACKGROUND: Acute decompensated aortic stenosis is an increasingly common condition associated with a high rate of morbidity, mortality, and health care resource utilization. Among patients with acute decompensated aortic stenosis, this study aimed to assess the impact of time to transcatheter aortic valve implantation (TAVI) on outcomes, hypothesizing that longer durations are associated with worse outcomes. METHODS: Using a single-center registry, patients with their first presentation of acute decompensated aortic stenosis who underwent an urgent TAVI during their index admission were included. Time to TAVI was defined as the number of days between hospital admission and TAVI. The primary composite outcome was heart failure hospitalization or all-cause mortality. The secondary composite outcome was heart failure hospitalization or cardiovascular mortality. RESULTS: A total of 276 patients were included in this study: age 84 (79–88) years, male sex 63.7%, patients requiring cardiopul

    Source: www.ahajournals.org
    Categories: General Medicine News
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      omendiz

      Importante en nuestro país para ver cómo cuando las autorizaciones se demoran tienen impacto en resultados #TAVI #EstenosisAortica 💔 https://t.co/OMh1e1tt6a https://t.co/pL81EiiDyM

  • Mashup Score: 1
    Outcomes of Transcatheter Aortic Valve Replacement in Low-Risk Patients in the United States: A Report From the STS/ACC TVT Registry | Circulation - 3 month(s) ago

    BACKGROUND: Real-world low-risk transcatheter aortic valve replacement (TAVR) outcomes in the United States have not been assessed comprehensively versus pivotal trials, which is a key component of measuring the quality of clinical technology adoption. METHODS: We identified heart team–designated low-risk patients undergoing TAVR for trileaflet severe, symptomatic aortic stenosis in the Society of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Registry, as well as a subset of patients who met low-risk trial inclusion and exclusion criteria, from January 2020 to March 2024. Outcomes (mortality, stroke, new pacemaker, and “alive and well,” defined as alive at 1 year with Kansas City Cardiomyopathy Questionnaire score ≥60 and ≤10-point decrease from baseline) at 30 days and 1 year were assessed. Multivariable models were developed to assess predictors of death within 1 year after TAVR. RESULTS: Among 383 030 patients who underwent TAVR during the study period, 108 40

    Source: www.ahajournals.org
    Categories: General Medicine News
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      omendiz

      Real life is not always the same than RCT. Outcomes of Transcatheter Aortic Valve Replacement in Low-Risk Patients in the United States: A Report From the STS/ACC TVT Registry | Circulation https://t.co/SiKSRaPuJZ

  • Mashup Score: 4
    Effect of TAVI on Epicardial Functional Indices and Their Relationship to Coronary Microvascular Function | Circulation: Cardiovascular Interventions - 3 month(s) ago

    BACKGROUND: The anatomic and physiological changes associated with severe aortic stenosis may influence the functional evaluation of coronary stenoses. In this study, we aimed to assess changes in functional resting and hyperemic indices before and immediately after transcatheter aortic valve implantation (TAVI) and their relationship with microvascular resistance. METHODS: In this pooled analysis of 3 prospective observational studies, fractional flow reserve (FFR), resting full-cycle ratio (RFR), and resting Pd/Pa were measured in patients with severe aortic stenosis before and after TAVI in the left anterior descending artery. Coronary microcirculation was also assessed using thermodilution-based methods, with microvascular resistance reserve (cutoff ≤3) used to identify coronary microvascular dysfunction. RESULTS: A total of 126 patients were included. Baseline Pd/Pa, RFR, and FFR measurements were 0.93±0.04, 0.90±0.07, and 0.89±0.07, respectively. Immediately post-TAVI, a small bu

    Source: www.ahajournals.org
    Categories: General Medicine News
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      Coronary Functional evaluation pre & post #TAVI #FFR #RFR https://t.co/QmfTCtIRSa https://t.co/ZvzQjs29ls

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