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Mashup Score: 1People with Lupus Who Have Certain Antibodies Are More Likely to Experience Blood Clots, Researchers Find - 8 day(s) ago
Some patients with lupus who possess specific antibodies are at a higher risk of thrombotic events such as a blood clot, stroke or heart attack, a new study led by Johns Hopkins Medicine researchers shows. The finding might help clinicians determine which patients may need early treatment and clinical monitoring for thrombotic events. Normally, antibodies help protect the body by fighting infections and tumors, but in autoimmune conditions such as lupus, antibodies may go after healthy tissues and
Source: www.hopkinsmedicine.orgCategories: General Medicine News, RheumatologyTweet
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Mashup Score: 0
and MeSH terms for “pain” and “manikin” to identify original studies in English that used a digital pain manikin for collecting information from adults with any condition. We extracted and descriptively synthesised data on the characteristics of studies and digital pain manikins and mapped them to a stage of the translational pathway (ie, design, testing, metric validation, and diffusion). We screened 6,189 articles, of which we included 104. Articles reported on 31 unique digital pain manikins. Most studies were conducted in Europe (n = 60; 58%), recruited people with pain/painful conditions (n = 69; 66%) from clinical settings (n = 67; 64%). Of the 31 manikins, the majority were two-dimensional (n = 21; 68%) with a front and back body view (n = 18; 58%) and allowed users to draw their pain on any area of the manikin (n = 23; 74%). Most manikins were still in the development and testing stages (n = 23; 74%). Only eight (26%) had progressed fully through the translational pathway, taki
Source: journals.lww.comCategories: General Medicine News, RheumatologyTweet
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Mashup Score: 0
ry, the expression and function of Kcnq4 channel in nociceptors remains unknown. Here we showed that Kcnq4 is substantially expressed by unmyelinated small-diameter DRG neurons in both human and mouse. In spite of a dispensable role in acute pain and chronic skin inflammation, Kcnq4 is specifically involved in the regulation of scratching behavior through controlling action potential firing properties, evidenced by the increased neuronal excitability in small-diameter DRG neurons isolated from Kcnq4 deficient mice. Moreover, genetic ablation of Kcnq4 in Trpv1-positive neurons exacerbates both acute and chronic itch behavior in mice. Taken together, our results uncover a functional role of Trpv1-lineage neuron-expressing Kcnq4 channel in the modulation of itch-specific neuronal excitation in the periphery….
Source: journals.lww.comCategories: General Medicine News, RheumatologyTweet
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Mashup Score: 0EULAR Research Funding | EULAR - 8 day(s) ago
EULAR Research Funding The EULAR Research Centre offers several funding opportunities for researchers and health professionals in rheumatology. Please find below more information about our ad-hoc funds (“Vouchers”), our dedicated Research Methods Grant, as well as other funding opportunities within EULAR and beyond. Improving Research Methods, Capabilities, and Processes Grant Focus on: Clinical RMD research methods This grant is intended to support the development of new tools, approaches and protocols
Source: www.eular.orgCategories: General Medicine News, RheumatologyTweet
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Mashup Score: 0Basics of Elbow Arthroscopy - 8 day(s) ago
Elbow arthroscopy can be utilized to treat a variety of elbow pathologies. With recent advancements in arthroscopic technology and our understanding of elbow anatomy, several approaches to elbow arthroscopy have been proposed. However, a “gold-standard” has yet to be defined. In this Technical Note, the authors describe a systematic approach to perform elbow arthroscopy in the lateral decubitus position. Strategic placement of portals reduces the risk of damage to neurovascular structures. Our surgical technique aims to offer a safe, reproducible method for achieving excellent visualization and access to both anterior and posterior compartments, thereby optimizing outcomes and minimizing complications.
Source: www.arthroscopytechniques.orgCategories: General Medicine News, RheumatologyTweet
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Mashup Score: 0
an OSA regimen than those not having an OSA regimen. Summary of Background Data. There has been a tremendous focus on opioid overuse. Accordingly, OSA regimens are being introduced to reduce narcotic use. However, OSA has not been studied in the adult spine deformity population. Methods. Forty-three patients undergoing fusion of at least five levels in the thoracolumbar spine received OSA. They were matched to 43 patients who did receive an OSA regimen. We analyzed several metrics including blood loss, anesthesia time, postanesthesia care unit (PACU) pain scores, postoperative pain scores, complications, length of stay, and readmissions. Results. The OSA group had significantly lower pain scores both before transfer to (4.6 vs. 7.6, P=0.000) and after transfer from (4.2 vs. 6.2 P=0.002) the PACU. Opioid use was significantly lower in the OSA group (454 vs. 241 MMEs by POD4, P=0.022). Fewer patients required blood transfusion in the OSA (1 vs. 28, P=0.000) group. Fewer patients in the O
Source: journals.lww.comCategories: General Medicine News, RheumatologyTweet
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Mashup Score: 0VMX - 8 day(s) ago
Virtual Meeting Experience
Source: my-congress.eular.orgCategories: General Medicine News, RheumatologyTweet
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Mashup Score: 0Differences in Talar Morphology Between Patients With Clubfoot and Nonclubfoot Patients from Fetus to Adulthood - 8 day(s) ago
The talus plays a central role in understanding the pathophysiology and natural history of clubfoot deformity. The morphology, severity, natural history, and functional implications of talar dysplasia in patients with…
Source: www.jbjs.orgCategories: General Medicine News, RheumatologyTweet
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Mashup Score: 4EULAR 2025 Barcelona: Questionnaire for Certificate of Attendance and Feedback Survey - 8 day(s) ago
Take this survey powered by surveymonkey.com. Create your own surveys for free.
Source: www.research.netCategories: General Medicine News, RheumatologyTweet
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Mashup Score: 1Increasing reaming depth enhances implant stability while minimizing bone strain | Bone & Joint - 8 day(s) ago
Increasing reaming depth enhances implant stability while minimizing bone strain
Source: boneandjoint.org.ukCategories: General Medicine News, RheumatologyTweet-
Enhancing cavity reaming depth is a simple technique to increase the implant primary stability of press-fit uncemented acetabular cupsomponents, while avoiding any excess in periacetabular strain and the associated fracture risk. #BJR #Fracture #Surgeon https://t.co/xMniJ78qa2 https://t.co/bO48ni9WXK
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Research led by Drs. Eduardo Gomez-Banuelos and Felipe Andrade at Johns Hopkins found that anti-TFAM antibodies are associated with thrombosis in patients with lupus. Learn more about these emerging findings and their potential here: https://t.co/kLYpPRGDom