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    • Mashup Score: 17
      Medical institutions must treat the Cass review as a significant event and act upon it - 11 month(s) ago

      Publication of the Cass review in April 2024 was a seminal moment in contemporary medicine. Hilary Cass, a consultant paediatrician, was commissioned by NHS England to report independently on “the services provided by the NHS to children and young people who are questioning their gender identity or experiencing gender incongruence.”1 The background was an increase in referrals—of mainly “birth registered females in early teenage years”—to gender identity clinics from 2014 at an “exponential rate.”2 The conclusions of the Cass review should not be surprising to anyone who has watched the promotion of medical interventions as necessary or curative in young people with gender dysphoria. As Cass states, there is a “lack of evidence” on the long term impact of hormonal prescriptions in young people, for example. Work now begins on how to design better, more evidence based, holistic services. The conclusion that services “must operate to the same standards as other services seeing children a

      Source: www.bmj.com
      Categories: General Medicine News, Oncologists1
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      • Profile photo of 	DrAllyCat
        DrAllyCat

        It’s important for clinical & research experts, medical orgs, 3rd sector & community to be given the voice to respond to the errors of the Cass review & those who would unquestioningly accept it. @bmj_latest has given BAGIS & @glaad that opportunity 🏳️‍⚧️ https://t.co/DK3kR4oSAl

    • Mashup Score: 11
      Rationale and design of the Self-TI Study protocol: a cross-sectional human papillomavirus self-testing pilot study among transgender adults in England - 12 month(s) ago

      Introduction Persistent infection with high-risk human papillomavirus (HPV) is the causal agent of several cancers including cervical, anal and oropharyngeal cancer. Transgender men and transmasculine non-binary (TMNB) people with a cervix are much less likely to undergo cervical cancer screening than cisgender women. Transgender women and transfeminine non-binary (TWNB) people assigned male at birth may be at increased risk of HPV. Both TMNB and TWNB people face many barriers to HPV testing including medical mistrust due to stigma and discrimination. Methods and analysis The Self-TI Study (Self-TI) is a pilot study designed to measure acceptability and feasibility of HPV self-testing among transgender and non-binary people in England. TMNB people aged 25–65 years, with at least 1 year of testosterone, and TWNB people, aged 18 years and over, are eligible to participate. Participants self-collect up to four samples: an oral rinse, a first void urine sample, a vaginal swab (if applicabl

      Source: bmjopen.bmj.com
      Categories: General Medicine News, Oncologists1
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      • Profile photo of 	DrAllyCat
        DrAllyCat

        Our protocol paper for #SelfTIStudy is out! https://t.co/VKWVI0sSt9 Thanks to @ssjac79 @ejoeyward Stewart O'Callaghan of @OUTpatientsUK @profchloeorkin Megan Clarke @theNCI & the whole study team! Come take part & improve HPV-screening for the #trans community! 🏳️‍⚧️ https://t.co/LEcfWQfA5Y

    • Mashup Score: 11
      Rationale and design of the Self-TI Study protocol: a cross-sectional human papillomavirus self-testing pilot study among transgender adults in England - 12 month(s) ago

      Introduction Persistent infection with high-risk human papillomavirus (HPV) is the causal agent of several cancers including cervical, anal and oropharyngeal cancer. Transgender men and transmasculine non-binary (TMNB) people with a cervix are much less likely to undergo cervical cancer screening than cisgender women. Transgender women and transfeminine non-binary (TWNB) people assigned male at birth may be at increased risk of HPV. Both TMNB and TWNB people face many barriers to HPV testing including medical mistrust due to stigma and discrimination. Methods and analysis The Self-TI Study (Self-TI) is a pilot study designed to measure acceptability and feasibility of HPV self-testing among transgender and non-binary people in England. TMNB people aged 25–65 years, with at least 1 year of testosterone, and TWNB people, aged 18 years and over, are eligible to participate. Participants self-collect up to four samples: an oral rinse, a first void urine sample, a vaginal swab (if applicabl

      Source: bmjopen.bmj.com
      Categories: General Medicine News, Oncologists1
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      • Profile photo of 	DrAllyCat
        DrAllyCat

        Our protocol paper for #SelfTIStudy is out! https://t.co/VKWVI0sSt9 Thanks to @ssjac79 @ejoeyward Stewart O'Callaghan of @OUTpatientsUK @profchloeorkin Megan Clarke @theNCI & the whole study team! Come take part & improve HPV-screening for the #trans community! 🏳️‍⚧️ https://t.co/LEcfWQfA5Y

    • Mashup Score: 1
      LGBTQ+ population faces greater cancer risks. Also faces barriers to care, studies show. - 1 year(s) ago

      LGBTQ+ people experienced discrimination in health care that prevented adequate screening and care, studies found. Doctors weren’t aware of the lapse.

      Source: www.usatoday.com
      Categories: General Medicine News, Oncologists2
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      • Profile photo of 	DrAllyCat
        DrAllyCat

        More coverage for LGBTQ cancer care at #ASCO24 from @shail_maingi - it even got into USA today! https://t.co/QKWxAp2LgX

    • Mashup Score: 28
      Help shape cancer research for the gender diverse community - OUTpatients - 1 year(s) ago

      Help shape cancer research for the gender diverse community – by taking part in the TransCRIPT project, supported by OUTpatients

      Source: outpatients.org.uk
      Categories: General Medicine News, Oncologists2
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      • Profile photo of 	DrAllyCat
        DrAllyCat

        Help shape #cancerresearch for the #transgender & gender diverse community! If you identify as trans, non-binary or gender diverse & have been affected by #cancer, take part in our patient and public involvement project, TransCRIPT. 🏳️‍⚧️ Find out more at: https://t.co/xFmC0IzaLM

    • Mashup Score: 20
      UK Cancer and Transition Service - Transplus - 1 year(s) ago

      Review of available evidence related to treatment decisions. Signposting to other important services such as therapy, psychosexual counselling, and fertility preservation. You will also have the option to participate in research to help improve cancer care for the trans and non-binary community. UCATS is a new service for the trans and non-binary community. 1 in 2 of us will get cancer at some point in our lifetime. For trans and non-binary people a cancer diagnosis may be made more difficult because of:

      Source: www.wearetransplus.co.uk
      Categories: General Medicine News, Oncologists2
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      • Profile photo of 	DrAllyCat
        DrAllyCat

        Pleasure chatting with Naman & Jo on @rad__chat ! We discuss #LGBTQ #cancercare , gender services and the intersection with oncology care, the work of @OUTpatientsUK and the UK Cancer and Transition Service: https://t.co/LwlLXPDqCn 🏳️‍⚧️🏳️‍🌈 We also touch on busy portfolio careers! https://t.co/qLgacufKxW

    • Mashup Score: 4
      Welcome to the Self-TI Study - 1 year(s) ago

      All the info about the Self-TI study to find out how common high-risk HPV is in transgender people in different body parts using self-sampling.

      Source: www.self-ti.com
      Categories: General Medicine News, Oncologists2
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      • Profile photo of 	DrAllyCat
        DrAllyCat

        A good news story in #transhealth right now. 🏳️‍⚧️ Fully coproduced and people compensated 💰for their time. Please share within your networks & consider taking part! Find out more at https://t.co/HpfFbHm9Iu or let @theFoxFisher tell you: https://t.co/tVI41cwayC #Selftistudy https://t.co/TCI0rMUR0h

    • Mashup Score: 19
      UK Cancer and Transition Service - Transplus - 1 year(s) ago

      Review of available evidence related to treatment decisions. Signposting to other important services such as therapy, psychosexual counselling, and fertility preservation. You will also have the option to participate in research to help improve cancer care for the trans and non-binary community. UCATS is a new service for the trans and non-binary community. 1 in 2 of us will get cancer at some point in our lifetime. For trans and non-binary people a cancer diagnosis may be made more difficult because of:

      Source: www.wearetransplus.co.uk
      Categories: General Medicine News, Oncologists2
      Tweet Tweets with this article
      • Profile photo of 	DrAllyCat
        DrAllyCat

        Pleasure chatting with Naman & Jo on @rad__chat ! We discuss #LGBTQ #cancercare , gender services and the intersection with oncology care, the work of @OUTpatientsUK and the UK Cancer and Transition Service: https://t.co/LwlLXPDqCn 🏳️‍⚧️🏳️‍🌈 We also touch on busy portfolio careers! https://t.co/qLgacufKxW

    • Mashup Score: 29
      Stabilising selection causes grossly altered but stable karyotypes in metastatic colorectal cancer - 1 year(s) ago

      Aneuploidy, defined as the loss and gain of whole and part chromosomes, is a near-ubiquitous feature of cancer genomes, is prognostic, and likely an important determinant of cancer cell biology. In colorectal cancer (CRC), aneuploidy is found in virtually all tumours, including precursor adenomas. However, the temporal evolutionary dynamics that select for aneuploidy remain broadly uncharacterised. Here we perform genomic analysis of 755 samples from a total of 167 patients with colorectal-derived neoplastic lesions that cross-sectionally represent the distinct stages of tumour evolution, and longitudinally track individual tumours through metastasis and treatment. Precancer lesions (adenomas) exhibited low levels of aneuploidy but high intra-tumour heterogeneity, whereas cancers had high aneuploidy but low heterogeneity, indicating that progression is through a genetic bottleneck that suppresses diversity. Individual CRC glands from the same tumour have similar karyotypes, despite pri

      Source: www.biorxiv.org
      Categories: General Medicine News, Oncologists2
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      • Profile photo of 	DrAllyCat
        DrAllyCat

        RT @trevoragraham: More distraction: new #preprint we posted a little while ago https://t.co/5niFLLkMK5 looks at somatic copy number #evolu…

    • Mashup Score: 51
      Equitable cancer care for the LGBTQIA+ community - 1 year(s) ago

      Read the second blog from our International Women’s Day series exploring the barriers to equitable cancer care for the LGBTQIA+ community.

      Source: www.macmillan.org.uk
      Categories: General Medicine News, Oncologists2
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      • Profile photo of 	DrAllyCat
        DrAllyCat

        Pleased to work with @macmillancancer on this blog on equitable #cancercare for #LGBTQ populations & feature work of some great individuals & organisations @OUTpatientsUK @DrEstherMoss1 @GIRESUK @DrJenOG @56TSoho @ssjac79 @hospiceuk #selftistudy 🏳️‍🌈 🏳️‍⚧️ https://t.co/81Lmamzcit

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    Alison May Berner 👩🏻‍⚕️🏳️‍🌈🧬👩🏻‍🔬

    @DrAllyCat

    Medical Oncologist 👩🏻‍⚕️ Cancer Researcher 🧪 & Gender Identity Specialist 🏳️‍🌈 Interested in genomics 🧬 epigenetics & trans health. Views my own. She/her.

    ASCO 2025

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