Nature Reviews Gastroenterology & Hepatology – Liver transplantation is challenged by organ scarcity and ageing donors. Machine perfusion is a promising technique to enhance organ preservation…
Nature Reviews Neurology – In this Consensus Statement, Leonhard et al. provide a globally applicable guideline for the diagnosis and management of Guillain–Barré syndrome, including…
Nature Reviews Neurology – In this Consensus Statement, Leonhard et al. provide a globally applicable guideline for the diagnosis and management of Guillain–Barré syndrome, including…
Nature Reviews Endocrinology – This Review briefly outlines the pathophysiology of type 1 diabetes mellitus and discusses therapeutic targets that have reached clinical trials, including…
Nature Biotechnology – Mouse stem cells that regenerate muscle are derived by organoid dedifferentiation of myoblasts.
Nature – Certain RIFINs from Plasmodium falciparum can bind to both inhibitory (KIR2DL1) and activating (KIR2DS1) immune receptors on natural killer cells, demonstrating the potential…
npj Precision Oncology – A temporal model of tumor-immune dynamics during the metastatic progression of high-grade serous ovarian cancer
The PREEMPT CRC study met its primary end points but with a lower magnitude of benefit than investigators had hoped.
Background and aims Quantifying systemic inflammation (SI) in acutely decompensated cirrhosis (ADC) is of major importance because SI is a driver of the most severe…
Background Tumour-infiltrating T cells can mediate both antitumour immunity and promote tumour progression by creating an immunosuppressive environment. This dual role is especially relevant in…
Immune checkpoint inhibitors (ICI) have led to breakthrough improvements in the management of malignancy including hepatocellular (HCC) and biliary tract cancer, improving decades-old standards of…
