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Mashup Score: 36Clinical-genomic Characterization Unveils More Aggressive Disease Features in Elderly Prostate Cancer Patients with Low-grade Disease - 1 month(s) ago
Using genomic classifier scores, older men with low-risk prostate cancer were shown to harbor more aggressive disease than younger patients. This suggests that elderly patients with presumed-indolent disease may harbor a more aggressive phenotype, possibly requiring more active treatment.
Source: www.eu-focus.europeanurology.comCategories: General Medicine News, UrologyTweet
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Mashup Score: 3Reprogramming of Androgen Receptor Activity in Castration-resistant Prostate Cancer is Shaped by Truncated Variants - 3 month(s) ago
The androgen receptor (AR) is a master regulator in prostate cancer, but the relevance of its truncated variants remains unclear. Using patient-derived models, we demonstrated that expression of the ARv567es variant reprograms AR activity, resulting in resistance to AR-directed treatments.
Source: www.eu-focus.europeanurology.comCategories: General Medicine NewsTweet-
RT @LukeSelth: Check out our new work exploring AR biology in advanced prostate cancer: https://t.co/SqZKXZ8kcR. We found that tumours expr…
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Mashup Score: 22Oncological Outcomes Following Robotic Postchemotherapy Retroperitoneal Lymph Node Dissection for Testicular Cancer: A Worldwide Multicenter Study - 5 month(s) ago
This large, multicenter study showed that robotic postchemotherapy retroperitoneal lymph node dissection is associated with acceptable intermediate-term oncological outcomes in appropriately selected patients. However, this complex surgery should be conducted at centers with expertise in testicular cancer and minimally invasive surgery.
Source: www.eu-focus.europeanurology.comCategories: General Medicine News, Hem/OncsTweet-
Oncological Outcomes Following Robotic Postchemotherapy Retroperitoneal Lymph Node Dissection for Testicular Cancer: A Worldwide Multicenter Study - European Urology Focus https://t.co/2uh7Wv2mCa
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Mashup Score: 0The Association of Obstructive Sleep Apnea with Urological Cancer Incidence and Mortality—A Systematic Review and Meta-analysis - 10 month(s) ago
Obstructive sleep apnea may correlate with an increased risk of developing kidney and bladder cancer, but not prostate cancer. We urge physicians to remain cognizant of this potential relationship, to facilitate management and enhance patient care.
Source: www.eu-focus.europeanurology.comCategories: General Medicine News, Hem/OncsTweet-
I wouldn't have expected that: The Association of Obstructive Sleep Apnea with Urological Cancer Incidence and Mortality—A Systematic Review and Meta-analysis https://t.co/pnX4G6rGwh
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Mashup Score: 36Testicular Germ Cell Tumors with Venous Tumor Thrombus: Prevalence, Presentation, and Management - 11 month(s) ago
Although testicular germ cell tumors are highly responsive to platinum-based chemotherapy, our study demonstrates that regression of venous tumor thrombus after chemotherapy alone is less likely. Thus, complex multidisciplinary management including venous tumor thrombectomy at the time of postchemotherapy retroperitoneal lymph node dissection is typically necessary.
Source: www.eu-focus.europeanurology.comCategories: General Medicine News, Hem/OncsTweet-
Testicular Germ Cell Tumors with Venous Tumor Thrombus: Prevalence, Presentation, and Management @EurUrolFocus @spsutkaMD @SpiessPhilippe @GTumors https://t.co/HuGJngmg2W
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Mashup Score: 1
Individual participant–data meta-analysis (IPDMA) can help in studying predictors of a treatment effect in subgroup analyses. Before starting an IPDMA, it is important to weigh the added benefits against the extra effort needed in comparison to performing an aggregate-data meta-analysis.
Source: www.eu-focus.europeanurology.comCategories: General Medicine News, UrologyTweet-
Challenges In Performing An Individual Participant–level Data Meta-analysis https://t.co/s99qANZoft @EurUrolFocus https://t.co/LvPzzQLAos
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Mashup Score: 2Impact of the Internet on Patient-Physician Communication - 1 year(s) ago
In this report, we discuss how health information on the internet can help or hurt communication between patients and doctors. We conclude that the internet can be helpful for patient-physician communication, but it depends on the quality of health information found and whether that information is discussed during medical visits.
Source: www.eu-focus.europeanurology.comCategories: General Medicine News, UrologyTweet-
RT @EurUrolFocus: Throwback Thursday: Impact of the Internet on Patient-Physician Communication https://t.co/m6aZLaWKm3 @AishaLangford…
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Mashup Score: 5
We summarize key lifestyle modifications that can both reduce the burden of urological disease and support planetary health. An important strategy is reducing meat and dairy consumption, and shifting toward sustainable plant-based dietary patterns. Encouraging active commuting (walking, cycling) and supporting community green spaces can jointly promote overall, urological, and planetary health.
Source: www.eu-focus.europeanurology.comCategories: General Medicine News, UrologyTweet-
RT @EurUrolFocus: Dietary and Lifestyle Recommendations that Align Patient and Planetary Health https://t.co/FycRFiYtH3 @Putnam_Cole @L…
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Mashup Score: 4Impact of Anaesthetist Volume on Radical Cystectomy Outcomes - 2 year(s) ago
Radical cystectomy (RC) is a gold standard treatment for aggressive bladder cancer. Higher surgical volumes through centralisation are associated with improved RC outcomes. The impact of anaesthetist experience and RC volume on outcomes is less clear.
Source: www.eu-focus.europeanurology.comCategories: General Medicine News, UrologyTweet-
RT @EurUrolFocus: Throwback Thursday: Impact of Anaesthetist Volume on Radical Cystectomy Outcomes https://t.co/3aJEI6NPUv @IJubber @Ka…
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Mashup Score: 5Evaluating the Certainty of Evidence in Evidence-based Medicine - 2 year(s) ago
The GRADE certainty of evidence (CoE) rating qualifies to what extent we can trust a body of evidence summarized in a systematic review. Concerns regarding five domains (study limitations, inconsistency, indirectness, imprecision, and publication bias) can lower confidence, and three domains (magnitude of effect, dose-response gradient, and residual confounding) under select circumstances may increase confidence in the CoE. A CoE rating should be provided for every outcome in a systematic review and every guideline recommendation.
Source: www.eu-focus.europeanurology.comCategories: General Medicine News, Hem/OncsTweet-
Evaluating the Certainty of Evidence in Evidence-based Medicine https://t.co/ADgtc6ehYX via @Daniel_Urologia et al https://t.co/U2B7mbc0cI
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@AmericanCancer @dr_coops @jeshoag @VickersBiostats @AmerUrological @ASCO @ASTRO_org @PCF_Science @wandering_gu @EdwardSchaeffer @NRGonc 9/x Gene expression profiles of men >75 yo w/ low grade PCa exhibit more aggressive genomic features than younger men https://t.co/YW751SdVYZ @Veracyte @Davicioni https://t.co/dfBLXVlzev