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Mashup Score: 1
We read with interest the recent AJKD perspective on point-of-care ultrasound (POCUS) in nephrology and appreciate the authors’ contributions to this field1. We agree that not only is it critical to advance POCUS in nephrology, but as a community, we must ensure that stringent quality criteria are established, maintained, and that competencies are re-evaluated periodically. Rigorous training with direct supervision is key. While the author’s emphasis on training is laudable, they omitted an important existing resource: The American Society of Diagnostic and Interventional Nephrology (ASDIN).
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet
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Mashup Score: 0American Journal of Kidney Diseases - 10 day(s) ago
With diabetes mellitus being a leading cause of kidney failure and earlier stages of CKD throughout much of the world, understanding how diabetes affects the kidneys and exploring new treatment options is of critical importance.
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet-
Understanding how diabetes affects the kidneys and exploring new treatment options is of critical importance. We present a special collection of articles on Diabetes and Kidney Disease: https://t.co/tlX3kOSfmz (FREE until July 1, 2025) https://t.co/j61Pjfh0TW
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Mashup Score: 10
Genome-wide association studies (GWAS) have become a valuable tool for identifying genetic loci associated with complex traits, including chronic kidney disease (CKD). However, GWAS have important limitations in establishing direct causal links between genetic loci and biological phenotypes or with providing insights into biological pathways. A recent study by Loeb et al,1 published in Nature Genetics, represents a pioneering advancement, addressing critical gaps in prior GWAS investigations and offering new methods for connecting genes identified by GWAS to their functional relevance in kidney disease.
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet-
In the Literature (@NatureGenet) commentary by Cassianne Robinson-Cohen and Joachim H. Ix: Tubular Epithelial Cells are the Genetic Epicenter for Kidney Function https://t.co/Z4Z0W2MZZZ (FREE) @VUMCKidney @ucsdnephrology https://t.co/wy36s2GfGH
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Mashup Score: 50
Calcineurin inhibitor (CNI) nephrotoxicity may occur any time after initiation of therapy, and can affect transplant or native kidneys and present as acute or chronic reductions in kidney function. Elevated serum CNI trough levels may help make the diagnosis, although CNI nephrotoxicity is not necessarily dose dependent. CNI can cause vasoconstriction and increased serum creatinine (Scr) in the absence of morphologic findings, so CNI toxicity can be suggested as the cause of an abrupt Scr rise without morphologic changes.
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet-
#RenalPath: CNI nephrotoxicity with TMA involving an arteriole (Jones silver stain). https://t.co/8CyB2EXxTi (FREE) https://t.co/7AMwbB6TxZ
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Mashup Score: 16Determinants of Caregiver Burden Among Spouses of Patients With Kidney Failure: A Qualitative Study - 11 day(s) ago
Spousal caregivers participate extensively in the care of patients with kidney failure. Although previous studies suggested that these caregivers experience a high burden, a comprehensive understanding of the determinants of this burden and strategies to alleviate it are needed. Therefore, this study sought to explore the contributing and alleviating determinants of burden in spousal caregivers of patients with kidney failure.
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet-
Determinants of Caregiver Burden Among Spouses of Patients With Kidney Failure: A Qualitative Study https://t.co/wnew6vZlMb #OpenAccess #VisualAbstract https://t.co/eJ1y5TBhEk
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Mashup Score: 41Electrolyte Abnormalities in a Man With Plasma Cell Leukemia - 12 day(s) ago
A 77-year-old man with a history of cardiac transplantation and pulmonary tuberculosis was admitted for initiation of chemotherapy for multiple myeloma. His kidney function had worsened over several months, which was attributed to multiple myeloma–related kidney disease. Large bilateral kidney cysts precluded biopsy. Upon admission, he was found to have elevated gamma fraction and high IgG κ light chain levels. A peripheral smear showed over 20% plasma cells, diagnostic of progression from multiple myeloma to plasma cell leukemia.
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet-
A 77-year-old man with history of cardiac transplant and pulmonary tuberculosis was admitted for initiation of chemotherapy for multiple myeloma. His kidney function had worsened over several months. What are the possible causes of hyponatremia? https://t.co/x0NADc2er1 (FREE) https://t.co/OwC7kagpvn
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Mashup Score: 9Use of Statins for Primary Prevention Among Individuals with CKD in the United States: A Cross-Sectional, Time-Trend Analysis - 12 day(s) ago
Chronic kidney disease (CKD) populations face an elevated risk of cardiovascular disease (CVD), yet many remain undertreated with statins for primary prevention of CVD despite meeting eligibility criteria. We examined trends in statin use for primary prevention among individuals with CKD before and after the release of the 2013 Kidney Disease: Improving Global Outcomes (KDIGO) guideline recommending statin use for lipid management in selected adults with CKD.
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet-
Use of Statins for Primary Prevention Among Individuals with CKD in the United States: A Cross-Sectional, Time-Trend Analysis https://t.co/HoYOI3wdGl @hopkinsneph #VisualAbstract https://t.co/r69jVpxyV6
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Mashup Score: 6Transplant Staff Awareness of Gender Disparities and the Evaluation of Women for Kidney Transplantation - 12 day(s) ago
Kidney transplantation is lifesaving treatment for the majority of people with end-stage kidney disease (ESKD), prolonging survival and improving quality of life compared with dialysis.1 However, access to transplantation is not equitable, with women being 10-20% less likely than men to start medical evaluation for transplantation once referred to a transplant center.2–4 Low provider awareness of gender disparities may perpetuate this unequal access, yet remains underexplored. Therefore, we aimed to assess staff awareness of gender disparities in transplant evaluation and its relationship to center-specific gender disparities in evaluation rates.
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet-
Transplant Staff Awareness of Gender Disparities and the Evaluation of Women for Kidney Transplantation https://t.co/JV20YXtMhv (FREE) @jade__buford @RachelPatzerPhD @StephenPastan @AnaRossiMD https://t.co/pywiOjGWIJ
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Mashup Score: 1Closing CKD Treatment Gaps: Why Practice Guidelines and Better Drug Coverage Are Not Enough - 13 day(s) ago
In 2017, more than 850 million people were estimated to have chronic kidney disease (CKD), which disproportionately affects low- and middle-income countries.1 Death from CKD is largely due to vascular disease,2 and CKD is an independent risk factor for atherosclerosis.3 The first study showing that statins improve cardiovascular outcomes in people with CKD was reported in 2003,4 with a larger pooled analysis confirming these benefits the following year.5 Subsequently, the Study of Heart and Renal Protection (SHARP) trial of 2011 demonstrated that statin-ezetimibe treatment significantly reduces the risk of cardiovascular events among people with G3a-G5 CKD.
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet-
@hopkinsneph Editorial by @Mesangialman, @ChristophWanne4, and @cellotonell: Closing CKD Treatment Gaps: Why Practice Guidelines and Better Drug Coverage Are Not Enough https://t.co/Dsk4ZZYrGw (FREE) https://t.co/zZcDN7nWGT
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Mashup Score: 8Systemic Inflammation and the Risks of Adverse Kidney Outcomes in Adults With Atherosclerotic Cardiovascular Disease - 13 day(s) ago
Inflammasome activation is involved in the pathogenesis of both atherosclerotic cardiovascular disease (ASCVD) and chronic kidney disease (CKD). This study investigated whether systemic inflammation, measured by C-reactive protein (CRP), is associated with adverse kidney outcomes in adults with ASCVD.
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet-
Systemic Inflammation and the Risks of Adverse Kidney Outcomes in Adults With Atherosclerotic Cardiovascular Disease https://t.co/j3FsXmiSvo #OpenAccess #VisualAbstract @FuEdouard @VladoPerkovic @KatherineTuttl8 @jjcarrero1 https://t.co/cCfClfu5yA
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Clarification on Existing Opportunities for POCUS Certifications for Nephrologists https://t.co/PbyJAL9WwO @danielwross4 @AJKDonline