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Mashup Score: 3Stability and heterogeneity in the antimicrobiota reactivity of human milk-derived immunoglobulin A - 2 year(s) ago
We analyze the ability of breast milk–derived immunoglobulin A (IgA) antibodies to bind bacteria commonly found within the preterm infant intestinal microbiota.
Source: Rockefeller University PressCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 0Somatic gain-of-function mutations in BUD13 promote oncogenesis by disrupting Fbw7 function - 2 year(s) ago
Chen et al. develop an algorithm to map enzyme-substrate-recognizing motif mutations in cancer and find BUD13 AGC kinase motif mutations fuel colon cancer growt
Source: Rockefeller University PressCategories: Hem/Oncs, Latest HeadlinesTweet-
Somatic gain-of-function mutations in BUD13 promote oncogenesis by disrupting Fbw7 function https://t.co/acQ5g1hjGa
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Mashup Score: 16Cancer cell plasticity and MHC-II–mediated immune tolerance promote breast cancer metastasis to lymph nodes - 2 year(s) ago
Lei et al. uncover that a subpopulation of breast cancer cells in the lymph node is marked by MHC-II expression in the absence of costimulatory molecules, which
Source: Rockefeller University PressCategories: General Medicine News, Latest HeadlinesTweet-
Study sheds light on how #breastcancer cells evade immune surveillance and survive in #lymphnodes @JExpMed https://t.co/b1jkMDgS5L https://t.co/PFAkKYeKob
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Mashup Score: 0Stunning of neutrophils accounts for the anti-inflammatory effects of clodronate liposomes - 2 year(s) ago
The authors show that the anti-inflammatory effects of clodronate liposomes do not result from the depletion of mononuclear phagocytes but from a functional stu
Source: Rockefeller University PressCategories: Cardiologists, Latest HeadlinesTweet-
Interesting paper-revealing that clodronate liposome exert their anti-inflammatory effects independent of monocytes/macrophages. Polymorphonuclear neutrophils ingested Clo-Lip in vivo, which resulted in their functional arrest. https://t.co/mkr371Mm3O
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Mashup Score: 9Transfer of nuclear and ribosomal material from Sox10-lineage cells to neurons in the mouse brain - 2 year(s) ago
Mayrhofer et al. report that neurons in the mouse central nervous system receive nuclear and ribosomal material from Sox10-lineage cells. They identified nuclea
Source: Rockefeller University PressCategories: General Medicine News, Latest HeadlinesTweet-
Researchers discover how some brain #cells transfer material to #neurons in mice @JExpMed https://t.co/rX0lFlzRvv https://t.co/FqcVLT3cmG
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Mashup Score: 5Differential regulation of cardiac sodium channels by intracellular fibroblast growth factors - 2 year(s) ago
Intracellular fibroblast growth factors (iFGF) regulate voltage-gated sodium (NaV) channel expression and gating. Using a mouse model and heterologous expressio
Source: Rockefeller University PressCategories: General Medicine News, Latest HeadlinesTweet-
Small proteins in the heart play big role @wustl https://t.co/vz5KuA5ghO https://t.co/Q7YxgVFoHX
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Mashup Score: 3Retinoic acid signaling during priming licenses intestinal CD103+ CD8 TRM cell differentiation - 2 year(s) ago
Qiu et al. demonstrate that retinoic acid signaling during T cell priming in the mesenteric lymph nodes licenses the differentiation of CD103+ CD8 tissue-reside
Source: Rockefeller University PressCategories: General Medicine News, Latest HeadlinesTweet-
Can controlling #retinoicacid be a key to preventing infections in the #gut? @stonybrooku @JExpMed https://t.co/x7XfS3sOVz https://t.co/vWPcvqli6l
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Mashup Score: 5Human PIK3R1 mutations disrupt lymphocyte differentiation to cause activated PI3Kδ syndrome 2 - 2 year(s) ago
Detailed analysis of patients with APDS2 and a novel mouse model of Pik3r1 LOF reveals multiple cellular defects, some of which are unique to APDS2 and not seen
Source: Rockefeller University PressCategories: General Medicine News, Latest HeadlinesTweet-
Insights into causes of rare genetic immune disorders @JExpMed https://t.co/xMWrSd27hk https://t.co/i5kKgz0KtV
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Mashup Score: 2Age-associated B cells are heterogeneous and dynamic drivers of autoimmunity in mice - 2 year(s) ago
Age-associated B cells are heterogeneous with respect to expression of memory and plasmablast markers. Unlike resting memory, ABCs are chronically activated, wi
Source: Rockefeller University PressCategories: General Medicine News, Latest HeadlinesTweet-
Targeting type of B cell could reduce lupus disease, study suggests @JExpMed https://t.co/f37y5SeTDV https://t.co/cjY3VwOmG8
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Mashup Score: 3
A G795A substitution in human colony stimulating factor 1 receptor (CSF1R) confers resistance to pharmacological inhibitors, enabling widespread engraftment of
Source: Rockefeller University PressCategories: Latest Headlines, NeurologyTweet-
“Engineering an inhibitor-resistant human CSF1R variant for microglia replacement” by Mathew Blurton-Jones et al. Journal of Experimental Medicine https://t.co/v0sER85Wxs
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Study shows #breastmilk contains unique set of #antibodies @JExpMed https://t.co/DrfAcUsP23 https://t.co/2CuH2yqS8S