-
Mashup Score: 8Cardiac Amyloidosis in Older Adults With a Focus on Frailty: JACC: Advances Expert Consensus - PubMed - 2 day(s) ago
Amyloidosis, which is caused by misfolded proteins that form amyloid fibrils, is predominantly diagnosed in older adults. Although previously considered a rare disease, increased awareness and noninvasive diagnostic methods have resulted in a rise in diagnoses. As a multisystem disease that affects …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine NewsTweet
-
Mashup Score: 70
The emergence of pathophysiological, epidemiologic, and genetic data strongly supports the causality for lipoprotein(a) [Lp(a)] in cardiovascular disease (CVD) and calcific aortic valve disease (CAVD). In parallel, novel Lp(a) lowering approaches have been developed that have re-invigorated clinical …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine NewsTweet
-
Mashup Score: 2Dietary inflammatory index and Alzheimer's disease mortality in a prospective cohort - PubMed - 2 day(s) ago
Higher DII levels were significantly associated with elevated AD mortality risk, highlighting the potential role of pro-inflammatory diets in AD-related outcomes.
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine NewsTweet
-
Mashup Score: 11Novel method for quantification of lipoprotein(a)-cholesterol: implications for improving accuracy of LDL-C measurements - PubMed - 2 day(s) ago
Current methods for determining “LDL-C” in clinical practice measure the cholesterol content of both LDL and lipoprotein(a) [Lp(a)-C]. We developed a high-throughput, sensitive, and rapid method to quantitate Lp(a)-C and improve the accuracy of LDL-C by subtracting for Lp(a)-C (LDL-Ccorr) …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine NewsTweet
-
Mashup Score: 5Guidelines 2.0: systematic development of a comprehensive checklist for a successful guideline enterprise - PubMed - 2 day(s) ago
The checklist will serve as a resource for guideline developers. Consideration of items on the checklist will support the development, implementation and evaluation of guidelines. We will use crowdsourcing to revise the checklist and keep it up to date.
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine NewsTweet
-
Mashup Score: 26
Multiple myeloma (MM) is characterized by genetic abnormalities in plasma cells, requiring precise genomic characterization for effective risk stratification and treatment. This study presents the Unique Molecular Assay (UMA) panel, a targeted DNA-sequencing approach designed to capture critical gen …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine NewsTweet-
#Myeloma Paper of the Day: Unique molecular assay, a next-generation sequencing targeted panel for efficient & comprehensive genomic profiling & risk stratification of myeloma, supports clinical decision-making & personalized treatment strategies: https://t.co/LNahc5EEgr. #mmsm https://t.co/rNyal7EvYj
-
-
Mashup Score: 0Association of Mediterranean, high-quality, and anti-inflammatory diet with dementia in UK Biobank cohort - PubMed - 2 day(s) ago
Greater adherence to Mediterranean, MIND, and high-quality diets is associated with a lower risk of dementia, while pro-inflammatory diets increase the risk. High-quality anti-inflammatory diets play a significant role in reducing the risk of dementia, with stronger effects observed in specific subg …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, Partners & KOLsTweet
-
Mashup Score: 3
The Limitations and Risks Associated With Semaglutide Treatment
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine NewsTweet
-
Mashup Score: 5
Individuals with a germline pathogenic variant in the CDH1 gene have a lifetime risk of advanced diffuse gastric cancer (DGC) of up to 10.3% and a 37%-52% risk of breast cancer, specifically the lobular subtype. Guidelines recommend prophylactic gastrectomy between ages 18-40 years for those …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, GastroenterologyTweet
-
Mashup Score: 0
This study found that psychotherapy use increased significantly faster among several socioeconomically advantaged groups and that inequalities were evident in teletherapy access. These trends and patterns highlight a need for clinical interventions and health care policies to broaden access to psych …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine NewsTweet
Comprehensive, multidimensional geriatric assessment is essential in managing cardiac amyloidosis. Frailty, functional status, cognition, and social support must be integrated into care planning to optimize outcomes. @BU_Amyloidosis https://t.co/LYoxEeHZTP