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    Objectives To investigate the effects of overwork on brain structure to better understand its impact on workers’ cognitive and emotional health. The goal was to provide evidence for the potential neurological risks associated with prolonged working hours. Methods A total of 110 healthcare workers were classified into overworked (≥52 hours/week; n=32) and non-overworked groups (n=78). Brain volume differences were assessed using voxel-based morphometry (VBM) and atlas-based analysis. General linear models adjusted for age, sex and total intracranial volume were applied, and correlation analyses explored relationships between weekly working hours and brain volume in regions with significant differences. Results Overworked individuals exhibited significant changes in brain regions associated with executive function and emotional regulation. Atlas-based analysis revealed a 19% increase in left caudal middle frontal gyrus volume in the overworked group compared with the non-overworked group

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    • Preliminary findings in @OEM_BMJ suggest that overwork may induce neuroadaptive changes in the brain that affect cognitive and and emotional health https://t.co/03tdfOyhgK