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Mashup Score: 0
Type 3 von Willebrand disease (VWD) is the most severe form of this disease owing to the almost complete deficiency of von Willebrand factor (VWF). Replacement therapy with plasma-derived products containing VWF or recombinant VWF rarely cause the development of alloantibodies against VWF that may be accompanied by anaphylactic reactions.
Categories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 3
Accurate measurements of coagulation factor activity form an essential part of hemophilia management and are performed by the one-stage or chromogenic assay. Current literature suggests that approximately one-third of persons with nonsevere hemophilia A exhibit assay discrepancy, albeit with a high variability between studies. Such data are scarce in nonsevere hemophilia B.
Categories: Hem/Oncs, Latest HeadlinesTweet-
Collaborative study from the Netherlands suggests that assay disprepancy in mild #hemophilia is much less common than previously reported. Our experience in Sheffield is very different than what is reported here. https://t.co/ls8TdYwKeu https://t.co/iOKs7A05qN
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Mashup Score: 0Recommendation on the Nomenclature for Anticoagulants: Updated Communication from the ISTH SSC Subcommittee on the Control of Anticoagulation - 2 year(s) ago
Oral anticoagulation therapy has evolved beyond vitamin K antagonists to include oral direct thrombin inhibitors and factor Xa inhibitors. Collectively known as ‘direct oral anticoagulants’, this class of medications represents the current standard of care for the prevention and treatment of common thrombotic disorders, including atrial fibrillation and venous thromboembolism. Medications that…
Categories: Hematologists1, Latest HeadlinesTweet-
🚨Nouvelle reco @ISTH nomenclature des anticoagulants ❌ On ne dit toujours pas NACO #NOAC 😇 ❌ On ne peut plus dire AOD #DOAC et on ne pourra pas dire AOD anti-FXIa 😢 ✅ Anti-Xa oral ✅ Anti-FXIa oral @GBarnesMD @LanaCastellucci @CukerMd https://t.co/offqTJw1gh https://t.co/dNdJtKQZCi
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Mashup Score: 0
Arterial thrombotic events, particularly ischemic stroke and myocardial infarction, are common, and mostly occur due to atherosclerotic disease or arrhythmias. The diagnosis and management of the majority of such events occurs without the involvement of a hematologist, following established guidelines or pathways. In this review, we discuss 3 scenarios in which optimal management is less certain….
Categories: Hematologists1, Latest HeadlinesTweet-
🚨A must read ➡️ Dilemmas in hematology: consults in patients with arterial thrombosis 🫀☄️🤓 https://t.co/PkDkKjSgP2 @connors_md @JTHjournal
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Mashup Score: 0Prevalence of pulmonary embolism among patients with recent onset of dyspnea on exertion. A cross-sectional study - 2 year(s) ago
Exertional dyspnea is a frequently encountered complaint in clinical practice. However, the prevalence of pulmonary embolism (PE) among patients with dyspnea on exertion has not been reported.
Categories: Latest Headlines, PulmonologyTweet-
New, significant dyspnea within the past month? 20% had PE without other VTE symptoms in one series. https://t.co/lLUtq8lHNM
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Mashup Score: 0
Few studies evaluated the performance of noninvasive diagnostic strategies for suspected acute pulmonary embolism (PE) in pregnant women.
Categories: Hematologists1, Latest HeadlinesTweet-
“From an efficiency perspective, the use of a strategy with pretest probability-adapted D-dimer threshold is preferred” Noninvasive diagnostic work-up for suspected acute PE during pregnancy: systematic review and meta-analysis of individual patient data https://t.co/tzfCBO4RON
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“Noninvasive diagnostic work-up for suspected acute PE during pregnancy: a systematic review and meta-analysis of individual patient data https://t.co/tzfCBO4RON
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Mashup Score: 0
Few studies evaluated the performance of noninvasive diagnostic strategies for suspected acute pulmonary embolism (PE) in pregnant women.
Categories: Hem/Oncs, Latest HeadlinesTweet-
IPDMA on diagnostic work-up for suspected acute #pulmonaryembolism during #pregnancy: very limited yield of CUS for DVT, esp in women without leg symptoms https://t.co/1GC940s1OW @Erik_Klok_MD @fniainle @grelegal @MathildeN1977
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Mashup Score: 1
Peripartum management of women using low-molecular-weight heparin (LMWH) varies widely. Minimum time intervals are required between LMWH injection and neuraxial procedure, and they differ by dose.
Categories: Hem/Oncs, Latest HeadlinesTweet-
📢Data on > 1000 🤰🏼women: onset of labor and use of analgesia in women using thromboprophylaxis with 2 doses of #LMWH: insights from the #Highlow study 1/2 https://t.co/h4R3JtZsR1
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Mashup Score: 2Beyond the guidelines: how we approach challenging scenarios in the diagnosis and management of von Willebrand disease - 2 year(s) ago
Although von Willebrand disease (VWD) is the most common inherited bleeding disorder, its diagnosis and management are often challenging. Clinical practice guidelines, developed through systematic review of the medical literature and considering the best available evidence, provide guidance for common clinical scenarios. However, in the clinical setting, patients often present with…
Categories: Hematologists1, Latest HeadlinesTweet-
Excited to begin 2023 with our brand new paper, on how we approach the many challenging scenarios in the diagnosis & management of #VWD. Proud to work with this amazing team, & publish my first @JTHjournal paper! @NTConnell @james_paulad @VeronicaFlood18 https://t.co/ljo9y8IFnH
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Impressive cohort study of 213 type 3 von Willebrand disease patients. Anti-VWF antibodies in 8.4% (approx half had anaphylactic reactions). Neutralising antibodies in 6%. https://t.co/5Autlj2DJv #Willebrand #VWD #VWF https://t.co/HsgB2eFe3k