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Mashup Score: 2Tumor Necrosis Factor Blocking Therapy and Congestive Heart Failure in Patients with Inflammatory Rheumatic Disorders: A Systematic Review - 2 year(s) ago
Introduction: Tumour necrosis factor (TNF) blocking therapy is an effective treatment for chronic inflammatory arthritis. As circulating TNF might induce or exacerbate the development of congestive heart failure (CHF), several trials have investigated the effect of TNF blocking therapy on CHF. However, due to inefficacy and even a risk of exacerbation of CHF, TNF blocking therapy has since then…
Source: http://www.eurekaselect.comCategories: Latest Headlines, RheumatologyTweet
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Mashup Score: 0
Lorcaserin is a 3-benzazepine that binds 5-HT2C serotonin receptors in the hypothalamus, where it mediates lack of hunger and/or satiety, and in the ventral tegmental area, the site of origin of the mesolimbic and mesocortical dopaminergic projections, which mediate pleasure and reward. The drug has been first developed for the treatment of obesity, where it has shown efficacy, and subsequently…
Source: http://www.eurekaselect.comCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 2
Introduction: Angiotensin-converting enzyme inhibitors (ACEI), angiotensin receptor blockers (ARB), angiotensin receptor-neprilysin inhibitor (ARNI), and mineralocorticoid receptor antagonists (MRA) reduce mortality and hospitalizations in heart failure with reduced ejection fraction (HFrEF) but their use is limited in advanced chronic kidney disease (CKD). Methods: We carried out a systematic…
Source: http://www.eurekaselect.comCategories: Cardiologists, Latest HeadlinesTweet-
Trans-Atlantic #cardiorenal collaborative work Liverpool team led by Prof @RangaswJ et al on “"Renalism" with RAASI use in pts Enrolled in Trials for #heartfailure with Reduced Ejection Fraction & Advanced #chronickidneydisease : A Systematic Review”https://t.co/VRGoFSh8Vi https://t.co/r5otBoaPzE
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Mashup Score: 0Targeted treatment and immunotherapy in high-risk and relapsed/refractory pediatric acute lymphoblastic leukemia - 3 year(s) ago
Acute lymphoblastic leukemia is the most frequent pediatric malignancy in children, comprising 30% of all pediatric malignancies; adult ALL comprises 5% of all ALL cases, which have a 186.6 per 1 million incidence. In pediatric ALL (pALL), on which this review focuses, approximately 1 in 285 children are diagnosed with cancer before the age of 20, and approximately 1 in 530 young adults between…
Source: http://www.eurekaselect.comCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 2
Chimeric antigen receptor (CAR) T-cell therapy has shown remarkable efficacy in treating highly refractory and relapsing hematological malignancies in pediatric and adult patients. However, this promising therapy is limited by severe and potentially life-threatening toxicities. Cytokine release syndrome (CRS) is the most commonly observed of these toxicities. The cardiovascular manifestations of…
Source: http://www.eurekaselect.comCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 0
Chimeric antigen receptor (CAR) T-cell therapy has shown remarkable efficacy in treating highly refractory and relapsing hematological malignancies in pediatric and adult patients. However, this promising therapy is limited by severe and potentially life-threatening toxicities. Cytokine release syndrome (CRS) is the most commonly observed of these toxicities. The cardiovascular manifestations of…
Source: http://www.eurekaselect.comCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 3Incidence, Current Guidelines and Management of Gastrointestinal Bleeding after Transcatheter Aortic Valve Replacement: A Systematic Review - 3 year(s) ago
Background: There is a significant increase in morbidity and mortality in patients complicated by major bleeding following transcatheter aortic valve replacement (TAVR). It has become more challenging to manage such complications when the patient needs to be on anticoagulation or antiplatelet agent post-procedure to prevent thrombotic/embolic complications. Methods: We performed a systematic…
Source: http://www.eurekaselect.comCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 12
Electronically generated electromagnetic fields (EMFs), including those used in wireless communication such as cell phones, Wi-Fi and smart meters, are coherent, producing very high electric and magnetic forces, which act on the voltage sensor of voltage-gated calcium channels to produce increases in intracellular calcium [Ca2+]i. The calcium hypothesis of Alzheimer’s disease (AD) has…
Source: http://www.eurekaselect.comCategories: Latest Headlines, NeurologyTweet
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Mashup Score: 7Social Media as a Means to Disseminate and Advocate Cardiovascular Research: Why, How, and Best Practices - 5 year(s) ago
Aims: To review the use of Social Media as a Means to Disseminate and Advocate Cardiovascular Research: Why, How, and Best Practices. Background: The use …
Source: http://www.eurekaselect.comCategories: CardiologistsTweet
Anti-TNF not contraindicated in inflammatory #arthritis with mild-moderate congestive #heart failure 👉🏼https://t.co/5XPN1aLjrr 🔸BDMARDS probably have favourable effects on #cardiac function 👉🏼https://t.co/3LD1Jk4bAV Via Michael Nurmohamed #eular2023 https://t.co/aTniZEW5ki