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Mashup Score: 0Tacrolimus initial steady state level in post-transplant cyclophosphamide-based GvHD prophylaxis regimens - Bone Marrow Transplantation - 3 year(s) ago
Post-transplant cyclophosphamide (PTCy) combined with tacrolimus (TAC) as graft-versus-host disease (GvHD) prophylaxis post-hematopoietic cell transplantation (HCT) is safe and effective. Optimal serum levels of TAC in this combination remain undetermined. We hypothesized that TAC at initial steady state (TISS) of <10 ng/mL could promote optimal transplant outcomes and prevent TAC-associated...
Source: Bone Marrow TransplantationCategories: Latest Headlines, TransplantationTweet
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Mashup Score: 6
Bone Marrow Transplantation –
Novel conditioning regimen for upfront haploidentical hematopoietic cell… Source: Bone Marrow TransplantationCategories: Hem/Oncs, Latest HeadlinesTweet-
Novel conditioning regimen for upfront #haploidentical hematopoietic cell transplantation in children with severe aplastic anemia and donor-specific anti-HLA antibodies @BMTjournal @hhashem84 #BMTsm #SAA https://t.co/AIVme4t3XZ
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Mashup Score: 0
We retrospectively compared the outcomes of reduced-intensity conditioning (RIC) transplantation from matched related donors (MRD; n = 266), matched unrelated donors (MUD; n = 277), and umbilical cord blood (UCB; n = 513) for mature lymphoid malignancies. The 3-year overall survival rates for the MRD, MUD, and UCB groups were 54%, 59%, and 40%, respectively (P < 0.001). Multivariate analysis...
Source: Bone Marrow TransplantationCategories: Latest Headlines, TransplantationTweet-
Impact of donor types on reduced-intensity conditioning allogeneic stem cell transplant for mature lymphoid malignancies @BMTjournal https://t.co/7I450y2TnD
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Mashup Score: 0
Autologous hematopoietic cell transplantation (HCT) is suitable for consolidation of favorable-/intermediate-risk AML patients in CR1. However, ~50% of AML patients relapse after autologous HCT, and efficacy of subsequent salvage strategies including allogeneic HCT remains unclear. We studied 123 consecutive patients with newly diagnosed AML undergoing high-dose chemotherapy (HDCT)/autologous HCT…
Source: Bone Marrow TransplantationCategories: Latest Headlines, TransplantationTweet-
Feasibility and efficacy of salvage allogeneic stem cell transplantation in AML patients relapsing after autologous stem cell transplantation @BMTjournal #bmtsm https://t.co/kq3KzLccZi
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Mashup Score: 2Statistics and measurable residual disease (MRD) testing: uses and abuses in hematopoietic cell transplantation - Bone Marrow Transplantation - 4 year(s) ago
The decision whether to recommend a transplant to someone with acute leukemia in first remission is complex and challenging. Diverse, often confounded co-variates interact to influence one’s recommendation. Briefly, the decision metric can be viewed in three spheres: (1) subject-; (2) transplant-; and (3) disease-related co-variates. Subject-related co-variates include items such as age and…
Source: Bone Marrow TransplantationCategories: Hem/Oncs, Latest HeadlinesTweet-
Such a great article on how to interpret MRD in hem malignancies. Every time I read it, I learn something new!! #leusm #mmsm #bmtsm https://t.co/0xWg8Lv5cH
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Mashup Score: 1
Despite recommendations for vaccination after hematopoietic cell transplantation (HCT), immunization rates remain low leaving children at high risk for vaccine preventable infections (VPIs). However, the burden from VPIs in pediatric HCT recipients is not well known. We describe the prevalence, risk factors, and outcomes of VPI-associated hospitalizations at centers participating in the Pediatric…
Source: Bone Marrow TransplantationCategories: Hematologists1, Latest HeadlinesTweet-
RT @AkshaySharmaMD: Vaccinations are critical for patients receiving #BMTsm @BMTjournal https://t.co/8OsMQi2Nsg
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Mashup Score: 1
Bone Marrow Transplantation –
Severe hyperammonemia in chimeric antigen receptor T cells… Source: Bone Marrow TransplantationCategories: Hem/Oncs, Latest HeadlinesTweet-
Severe hyperammonemia in #CARTcells recipient—unusual differential diagnosis of encephalopathy syndrome @BMTjournal https://t.co/F57VXRk3yR
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Mashup Score: 0
Bone Marrow Transplantation –
Long-term survival in a fraction of patients with metastatic breast cancer… Source: Bone Marrow TransplantationCategories: Latest Headlines, Oncologists1Tweet-
High-dose chemotherapy with autologous transplant in metastatic breast cancer after year 2000 shows that 14.2% of patients being progression free and alive at 5 years via @TheEBMT There is a subset who does well. #bcsm https://t.co/XTVSkJWyaz
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Mashup Score: 0
The combination of venetoclax (ven) and azacitidine (aza) has resulted in high response rates in the upfront treatment of AML in patients age > 75 and patients unfit for intensive chemotherapy. Given the poor historical outcomes in patients age ≥ 60 treated with induction chemotherapy, ven/aza has become our institutional preference for the initial treatment of non-core binding factor (CBF) AML…
Source: Bone Marrow TransplantationCategories: Hem/Oncs, Latest HeadlinesTweet-
Venetoclax and azacitidine followed by allogeneic transplant results in excellent outcomes and may improve outcomes versus maintenance therapy among newly diagnosed AML patients older than 60 @BMTjournal https://t.co/rtFbqfWdKa
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Mashup Score: 0Cognitive impairment in candidates for allogeneic hematopoietic stem cell transplantation - Bone Marrow Transplantation - 4 year(s) ago
Hematopoietic cell transplant (HCT) is an increasingly common and curative treatment strategy to improve survival among individuals with malignant and nonmalignant diseases, with over one million HCTs having been performed worldwide. Neurocognitive dysfunction is a common and untoward consequence of HCT for many recipients, although few studies have examined the profile of neurocognitive…
Source: Bone Marrow TransplantationCategories: Hem/Oncs, Latest HeadlinesTweet-
Cognitive impairment in candidates for allogeneic hematopoietic stem cell transplantation @BMTjournal https://t.co/Og0KdOLPrA
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Tacrolimus initial steady state level in post-transplant cyclophosphamide-based GvHD prophylaxis regimens @BMTjournal https://t.co/q5cbxwM0uF