Leveraging A Randomized Trial to Assess Relationships between Transeptal Puncture, Brain Emboli, and Migraine Symptoms
Catheter ablation procedures with transseptal punctures (usually for atrial fibrillation) are often associated with migraine-related visual auras, but the mechanism remains unknown. Whether this phenomenon is mediated by the creation of an atrial septal defect from transseptal puncture, or alternatively by silent acute brain emboli detected on magnetic resonance imaging (MRI) related to the procedure, remains to be investigated.