What are the molecular targets of inhaled anesthetics, such as isoflurane? This study reports that isoflurane binds type 1 ryanodine receptor, and determines that genetically disrupting a specific residue or pharmacologically activating this binding site with novel agonists can modulate sensitivity to anesthesia.
The editors reserve the right to choose whether manuscripts will publish in print or online-only. Manuscripts published “online-only” will not appear in print but will…
Artificial intelligence (AI) models, frequently built using deep neural networks (DNNs), have become integral to many aspects of modern life. However, the va…
BackgroundThe NeuroArtP3 (NET-2018-12366666) is a multicenter study funded by the Italian Ministry of Health. The aim of the project is to identify the progn…
Regardless of discipline, quantitative literacy is a critical component of any scientist’s skill set. A recent push from the NINDS has focused on enhancing and…
The Department of Neurology at The Ohio State University Wexner Medical Center is recruiting BC/BE Neurohospitalists
Brain-computer interface (BCI) is a novel human-computer interaction technology, and its rapid development has led to a growing demand for skilled BCI profes…
Nurtec ODT (rimegepant; Pfizer, New York, NY) treatment for acute migraine was found to have superior or comparable efficacy and a more favorable safety p…
Background and ObjectivesThe field of neurology has inherent uncertainty, and there is currently a limited focus on how to navigate uncertainty in formal neurology training.…
The 11th European Academy of Neurology congress will be on 21-24 June 2025, in Helsinki, Finland
ObjectivesInvestigate the association between advance care planning and decision regret among stroke surrogate decision makers.MethodsPeople hospitalized with ischemic or hemorrhagic stroke and their surrogate decision…
