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Mashup Score: 0
Microbial imbalance linked to MS severity. Study reveals diagnostic potential of gut microbiome ratios.
Source: www.emjreviews.comCategories: General Medicine News, NeurologyTweet
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Mashup Score: 3Brain Health Summit 2025 - 5 day(s) ago
The European Academy of Neurology (EAN), together with our Brain Health Mission (BHM) initiative, is proud to host the European Brain Health Summit 2025. Building on the successes of previous years, this year’s Summit will once again unite leading voices from across the globe to broaden the dialogue on brain health. As in past years, the event will serve as a platform for healthcare professionals, policymakers, researchers, and patient advocates to exchange ideas and advance progress towards improving
Source: www.ean.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 3
Electrophysiology recordings from the brain using laminar multielectrode arrays allow researchers to measure the activity of many neurons simultaneously. However, laminar microelectrode arrays move relative to their surrounding neural tissue for a variety of reasons, such as pulsation, changes in intracranial pressure, and decompression of neural tissue after insertion. Inferring and correcting for this motion stabilizes the recording and is critical to identify and track single neurons across time. Such motion correction is a preprocessing step of standard spike-sorting methods. However, estimating motion robustly and accurately in electrophysiology recordings is challenging due to the stochasticity of the neural data. To tackle this problem, we introduce MEDiCINe ( M otion E stimation by Di stributional C ontrastive I nference for Ne urophysiology), a novel motion estimation method. We show that MEDiCINe outperforms existing motion estimation methods on an extensive suite of simulate
Source: www.eneuro.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 9
1 Sichuan Provincial Center for Mental Health, Sichuan Provincial People’s Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China 2 Medical College, Macau University of Science and Technology, Chengdu, Sichuan, China 3 Institute Office, Sichuan Third People’s Hospital, Sichuan Nursing Vocational College Affiliated Hospital, Chengdu, Sichuan, China 4 Department of Medical, Sichuan Provincial People’s Hospital, School of Medicine, University of Electronic
Source: www.frontiersin.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 5Frontiers | GABAergic integration of transient and persistent neurons in the developing mouse somatosensory cortex - 5 day(s) ago
Institute of Physiology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany GABA is an essential element in the function of neocortical circuits. The origin, migration and mechanisms of synaptogenesis of GABAergic neurons have been intensively studied. However, little information is available when GABAergic synapses are formed within the different cortical layers, neuronal cell types and subcellular compartments. To quantify the distribution of GABAergic synapses in the
Source: www.frontiersin.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 2Hawkmoth Pheromone Transduction Involves G-Protein–Dependent Phospholipase Cβ Signaling - 5 day(s) ago
Evolutionary pressures adapted insect chemosensation to their respective physiological needs and tasks in their ecological niches. Solitary nocturnal moths rely on their acute olfactory sense to find mates at night. Pheromones are detected with maximized sensitivity and high temporal resolution through mechanisms that are mostly unknown. While the inverse topology of insect olfactory receptors and heteromerization with the olfactory receptor coreceptor suggest ionotropic transduction via odorant-gated receptor–ion channel complexes, contradictory data propose amplifying G-protein–coupled transduction. Here, we used in vivo tip-recordings of pheromone-sensitive sensilla of male Manduca sexta hawkmoths at specific times of day (rest vs activity). Since the olfactory receptor neurons distinguish signal parameters in three consecutive temporal windows of their pheromone response (phasic; tonic; late, long-lasting), respective response parameters were analyzed separately. Disruption of G-pr
Source: www.eneuro.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 1The Bad Medicine of Doctored - 5 day(s) ago
This Viewpoint discusses a recent book that alleges scientific misconduct in Alzheimer disease (AD) research; summarizes actual progress made in the field; suggests that the book contributes to a narrative that jeopardizes momentum in AD research; and calls for increased transparency and public…
Source: jamanetwork.comCategories: General Medicine News, NeurologyTweet
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Mashup Score: 4Frontiers | Investigating the psychophysiological effects of NaiKan Therapy: salivary oxytocin and cortisol release - 5 day(s) ago
1 Nanhui Mental Health Center, Shanghai, China 2 Fudan University, Shanghai, China 3 Shanghai Sipo Polytechnic, Shanghai, China NaiKan Therapy, a method of self-reflection and introspection, has garnered considerable interest for its psychological benefits. However, its physiological impacts, particularly on hormonal regulation, remain underexplored. In this study, we aimed to investigate the effects of NaiKan Therapy on salivary oxytocin and cortisol release, shedding light on the psychophysiological
Source: www.frontiersin.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 8
1 Oxford Centre for Human Brain Activity, Wellcome Centre for Integrative Neuroimaging, Department of Psychiatry, University of Oxford, Oxford, United Kingdom 2 Brain and Mind Centre, School of Medical Sciences, University of Sydney, Sydney, NSW, Australia 3 Centre for Human Brain Health, School of Psychology, University of Birmingham, Birmingham, United Kingdom We describe OHBA Software Library for the analysis of electrophysiology data (osl-ephys). This toolbox builds on top of the widely used MNE-Python
Source: www.frontiersin.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 8Revolutionizing ALS Treatment: The Tofersen Breakthrough - 5 day(s) ago
Dr. Gordon Smith talks with Dr. Timothy Miller about compelling patient stories and clinical data that highlight the potential for recovery in ALS patients, emphasizing the importance of early intervention and understanding the disease mechanisms. Disclosures can be found at .
Source: directory.libsyn.comCategories: General Medicine News, NeurologyTweet
Scientists have identified a specific gut microbiome ratio that could serve as a marker for disease severity. Learn more: https://t.co/BD0XbMLfQm