Frontiers | Role of glial cells in motor neuron degeneration in hereditary spastic paraplegias
1 Department of Biomedical Sciences, University of Illinois College of Medicine Rockford, Rockford, IL, United States 2 Department of Bioengineering, University of Ill inois at Chicago, Chicago, IL, United States This review provides a comprehensive overview of hereditary spastic paraplegias (HSPs) and summarizes the recent progress on the role of glial cells in the pathogenesis of HSPs. HSPs are a heterogeneous group of neurogenetic diseases characterized by axonal degeneration of cortical motor
