Frontiers | Physiological roles of embryonic microglia and their perturbation by maternal inflammation
Department of Anatomy and Cell Biology, Graduate School of Medicine, Nagoya University, Nagoya, Japan The interplay between the nervous and immune systems is well documented in the context of adult physiology and disease. Recent advances in understanding immune cell development h ave highlighted a significant interaction between neural lineage cells and microglia, the resident brain macrophages, during developmental stages. Throughout development, particularly from the embryonic to postnatal stages,