Association Between Automated Coronary Artery Calcium From Routine Chest Computed Tomography Scans and Cardiovascular Risk in Patients With Colorectal or Gastric Cancer | Circulation: Cardiovascular Quality and Outcomes
BACKGROUND: As cardiovascular disease (CVD) is the leading cause of noncancer mortality in colorectal or gastric cancer patients, it is essential to identify patients at increased CVD risk. Coronary artery calcium (CAC) is an established predictor of atherosclerotic CVD; however, its application is limited in this population. This study evaluates the association between automated CAC scoring using chest computed tomography and atherosclerotic CVD risk in colorectal or gastric cancer patients. METHODS: A retrospective cohort study was conducted using electronic health records linked to claims data of colorectal or gastric cancer patients who underwent non-ECG-gated chest computed tomography at 2 tertiary hospitals in South Korea between 2011 and 2019. CAC was automatically quantified using deep learning software and used to classify patients into 4 groups (CAC=0, 0400). The primary outcome was major adverse cardiovascular events (myocardial infarction, stroke, or cardiovascular mortalit
