Alteplase for Acute Ischemic Stroke at 4.5 to 24 Hours
This randomized clinical trial examines the safety and efficacy of intravenous alteplase administered 4.5 to 24 hours after stroke onset in patients with salvageable brain tissue.
This randomized clinical trial examines the safety and efficacy of intravenous alteplase administered 4.5 to 24 hours after stroke onset in patients with salvageable brain tissue.
ed understanding for serious illness conversations, especially for older adults with end stage kidney disease (ESKD). Methods: We conducted a qualitative study of older adults…
This randomized clinical trial assesses the effect of structured vs self-guided multidomain lifestyle interventions on changes in global cognitive function over 2 years among older…
This case report describes a male individual in his 50s with a history of primary sclerosing cholangitis who had undergone 2 liver transplants and had…
This Viewpoint assesses how routine outcomes monitoring can affect mental health outcomes and practitioners’ clinical skills.
This cross-sectional study explores changes in intravenous fluid use and clinical outcomes of pediatric patients treated in US emergency departments after Hurricane Helene in 2024.
This cross-sectional study examines county-level trends in labor after cesarean delivery access across the US from 2016 to 2021.
This Clinical Insights describes the process for initiating feminizing gender-affirmative hormone therapy for transgender women or nonbinary people.
This cohort study examines breast cancer outcomes in transgender and gender-diverse patients compared with cisgender patients, including overall survival and sociodemographic characteristics.
This randomized clinical trial assesses the effects of subcutaneous semaglutide on alcohol consumption in adults with alcohol use disorder.
Acute cellular rejection, also called acute T-cell–mediated rejection (TCMR), presents in the transplant recipient with acute kidney injury and decreased urine output, and may be…