Membranous nephropathy (MN) is an immune complex disease caused by subepithelial deposits. Primary MN is a common cause of nephrotic syndrome. About a third of patients reach remission, a third are stable, and a third have progressive loss of kidney function and persistent proteinuria. The phospholipase A2 receptor (PLA2R), expressed on podocytes, is the antigen in about 70% of patients with…
Accurate ascertainment of end-stage kidney disease (ESKD) in electronic health records (EHRs) data is important for much epidemiological research. This study aimed to develop and…
Heart failure (HF) and kidney disease are intricately linked.1 Approximately 10%-30% of patients with chronic kidney disease (CKD) have HF, while ∼30%-60% of patients with…
The prevalence of end-stage kidney disease (ESKD) continues to rise, with socioeconomic status (SES), particularly income, having associations with ESKD risk among individuals with type…
Mixed acid-base disorders are frequently encountered in clinical practice and due to their complexity, diagnoses and treatment are challenging. The opposing effects of multiple disturbances…
This image depicts the finitude that some young women receiving peritoneal dialysis can face. Their lives can be limited and uncertain. Their abilities to achieve…
Patients with CKD often face mental health problems, but the burden of severe mental illness (SMI) in this population is unclear. We estimated the prevalence…
Acute kidney injury (AKI) and chronic kidney diseases (CKD) are clear concepts, based on internationally recognised consensus definitions, that are understood and usefully applied by…
We are delighted to highlight the top cited Original Investigations published in 2020 and 2021 that contributed to AJKD’s 2022 Impact Factor of 13.2, our…
Dr. Somaya Zahran is a Nephrology fellow and Chief Fellow at McGill University in Montreal, Canada. She earned her medical degree in Egypt and completed…
The iBox (Integrative Box) risk prediction score, integrating functional, immunological, and histological factors, offers a novel method for predicting the risk of death-censored graft failure…
