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Mashup Score: 0
The causes for disparities in implementation of precision medicine are complex, due in part to differences in clinical care and a lack of engagement and recruitment of under-represented populations in studies. New tools and large genetic cohorts can change these circumstances and build access to personalized medicine for disadvantaged populations.
Source: Trends in GeneticsCategories: Genetics, Latest HeadlinesTweet
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Mashup Score: 2Be the Change You Wish to See - 5 year(s) ago
I write this editorial full of optimism and hope for all that the future holds. The past few months have literally changed the course of history for humankind. It has exposed the vulnerabilities of the entire human race and served as a reminder of why it’s worth investing in scientific research for the betterment of our future.
Source: Trends in GeneticsCategories: Genetics, Latest HeadlinesTweet
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Mashup Score: 10Meiotic Executioner Genes Protect the Y from Extinction - 5 year(s) ago
The Y has been described as a wimpy degraded relic of the X, with imminent demise should it lose sex-determining function. Why then has it persisted in almost all mammals? Here we present a novel mechanistic explanation for its evolutionary perseverance: the persistent Y hypothesis. The Y chromosome bears genes that act as their own judge, jury, and executioner in the tightly regulated meiotic…
Source: Trends in GeneticsCategories: Genetics, Latest HeadlinesTweet
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Mashup Score: 1Search and Capture: Disorder Rules Gene Promoter Selection - 5 year(s) ago
Intrinsically disordered regions (IDRs) are preponderant in transcription factors (TFs) and are evolutionarily less conserved vis-à-vis DNA-binding do…
Source: www.sciencedirect.comCategories: Genetics, Latest HeadlinesTweet
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Mashup Score: 4A Way Straight-Forward for Leishmania Genetics - 5 year(s) ago
Genetic exchange between Leishmania parasites was demonstrated in sandflies over 10 years ago. Louradour et al. have shown in vitro hybridization of two Leishmania tropica isolates, with the potential to remove a major roadblock to using forward genetics in Leishmania, understanding Leishmania reproductive biology, and analyzing gene flow in natural populations.
Source: Trends in ParasitologyCategories: Genetics, Latest HeadlinesTweet
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Mashup Score: 0
Whole-genome sequencing is accelerating identification of noncoding variants that disrupt gene expression, although reports of such regulatory variants implicated in disease remain rare. A notable subset of described variants affect transcription factor (TF) genes and other master regulators in cis through dosage effects. From the literature, we compiled 46 regulatory variants linked to 40 TF…
Source: Trends in GeneticsCategories: Genetics, Latest HeadlinesTweet
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Mashup Score: 1
You can now book and manage appointments using our booking page.
Source: outlook.office365.comCategories: Genetics, Latest HeadlinesTweet
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Mashup Score: 0The invisible university is COVID-19 positive - 5 year(s) ago
Within the ivory tower, the COVID-19 pandemic stands to disproportionately impact the invisible workforce of postdoctoral researchers. Faced with university closures, hiring freezes and a general lack of support and benefits, an entire generation of Ph.Ds. and their knowledge and skills may be lost to academia without intervention.
Source: Trends in GeneticsCategories: Genetics, Latest HeadlinesTweet
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Mashup Score: 21AACR Virtual Annual Meeting II | Overview | AACR Meetings - 5 year(s) ago
The AACR Virtual Annual Meeting II will present a complete educational program. The program will also feature an Opening Plenary Session.
Categories: Hem/Onc News and Journals, Latest HeadlinesTweet-
RT @AACR: Free registration for the #AACR20 Virtual Annual Meeting II (June 22-24) is now open. Sign up today: https://t.co/WoUAWzvGrI http…
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Mashup Score: 1Tracking the genomic footprints of SARS-CoV-2 transmission - 5 year(s) ago
There is considerable public and scientific interest on the origin, spread and evolution of SARS-CoV-2. A recent study by Lu et al. [1], conducted genomic sequencing and analysis of SARS-CoV-2 in Guangdong, revealing its early transmission out of Hubei and shedding light on the effectiveness of controlling local transmission chains.
Source: Trends in GeneticsCategories: Genetics, Latest HeadlinesTweet
Now online a thought-provoking Science and Society article on Equity in health: Consideration of Race and Ethnicity in #PrecisionMedicine written by @Velez_Edwards @toddledwards @JosephBreeyear @JackiePickos https://t.co/WTEnAMCTOH