• Mashup Score: 0

    The causes for disparities in implementation of precision medicine are complex, due in part to differences in clinical care and a lack of engagement and recruitment of under-represented populations in studies. New tools and large genetic cohorts can change these circumstances and build access to personalized medicine for disadvantaged populations.

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    • Now online a thought-provoking Science and Society article on Equity in health: Consideration of Race and Ethnicity in #PrecisionMedicine written by @Velez_Edwards @toddledwards @JosephBreeyear @JackiePickos https://t.co/WTEnAMCTOH

  • Mashup Score: 2

    I write this editorial full of optimism and hope for all that the future holds. The past few months have literally changed the course of history for humankind. It has exposed the vulnerabilities of the entire human race and served as a reminder of why it’s worth investing in scientific research for the betterment of our future.

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    • RT @Muliyilsonia: My first ever Editorial for the September issue of @TrendsGenetics Enjoyed writing it! https://t.co/uETdKIfsN7

  • Mashup Score: 10

    The Y has been described as a wimpy degraded relic of the X, with imminent demise should it lose sex-determining function. Why then has it persisted in almost all mammals? Here we present a novel mechanistic explanation for its evolutionary perseverance: the persistent Y hypothesis. The Y chromosome bears genes that act as their own judge, jury, and executioner in the tightly regulated meiotic…

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    • RT @HarmitMalik: Very cool hypothesis! https://t.co/eOABBeOMtY

  • Mashup Score: 4

    Genetic exchange between Leishmania parasites was demonstrated in sandflies over 10 years ago. Louradour et al. have shown in vitro hybridization of two Leishmania tropica isolates, with the potential to remove a major roadblock to using forward genetics in Leishmania, understanding Leishmania reproductive biology, and analyzing gene flow in natural populations.

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    • RT @bloodSparasites: A Way Straight-Forward for Leishmania Genetics https://t.co/3ohrQwBOJR @TrendsParasitol https://t.co/DjTm9cQwUv

  • Mashup Score: 0

    Whole-genome sequencing is accelerating identification of noncoding variants that disrupt gene expression, although reports of such regulatory variants implicated in disease remain rare. A notable subset of described variants affect transcription factor (TF) genes and other master regulators in cis through dosage effects. From the literature, we compiled 46 regulatory variants linked to 40 TF…

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    • Read an interesting #OA article in our July issue that discusses Disease causing cis variants in Transcription factor genes by @WyWyWa @robinvdlee @CorreardSolenne https://t.co/qa8Ta6s55a

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    Within the ivory tower, the COVID-19 pandemic stands to disproportionately impact the invisible workforce of postdoctoral researchers. Faced with university closures, hiring freezes and a general lack of support and benefits, an entire generation of Ph.Ds. and their knowledge and skills may be lost to academia without intervention.

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    • #COVID19 poses problems for all academics. However, it "stands to disproportionately impact the invisible workforce of postdoctoral researchers". Read a Scientific Life article by Daniel Park, now online https://t.co/2WO7ygm099

  • Mashup Score: 1

    There is considerable public and scientific interest on the origin, spread and evolution of SARS-CoV-2. A recent study by Lu et al. [1], conducted genomic sequencing and analysis of SARS-CoV-2 in Guangdong, revealing its early transmission out of Hubei and shedding light on the effectiveness of controlling local transmission chains.

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    • Check out our recently accepted #openaccess Spotlight on a @CellPressNews paper, assessing the genomic footprints of #Covid19 transmission in Guangdong https://t.co/teQDUlWR5E