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Mashup Score: 0Closing the Gap in Cancer Genomic Testing | NEJM - 3 year(s) ago
Perspective from The New England Journal of Medicine — Closing the Gap in Cancer Genomic Testing
Source: New England Journal of MedicineCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 1
Oncologists and specialists at City of Hope in Los Angeles are extending genomic analysis to new patients, unlocking precision treatments and improved preventive care for those living with cancer — and their families.
Source: www.nature.comCategories: Hem/Oncs, Latest HeadlinesTweet-
At City of Hope we’re aiming to extend molecular testing and precision treatments to a wider population. Learn how in this @NaturePortfolio feature on City of Hope’s Center for Precision Medicine and City of Hope’s Division of Clinical Cancer Genomics. https://t.co/9DDb3UnD4s
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Mashup Score: 6Leveraging an Informatics Approach to Identify an Unmet Clinical Need for BRCA1/2 Testing Among Patients With Ovarian Cancer - 3 year(s) ago
PURPOSE Although BRCA1/2 testing in ovarian cancer improves outcomes, it is vastly underutilized. Scalable approaches are urgently needed to improve genomically guided care. METHODS We developed a Natural Language Processing (NLP) pipeline to extract electronic medical record information to identify recipients of BRCA testing. We applied the NLP pipeline to assess testing status in 308 patients…
Source: JCO Clinical Cancer InformaticsCategories: Hem/Oncs, Latest HeadlinesTweet-
1/ Genetic testing should be a core element of care for all patients with #ovariancancer. However, nationally, only ~30% of women are tested. We developed & applied an NLP algorithm to EHR data to rapidly identify women who need testing. https://t.co/0JGGuryl6c https://t.co/HZ2mQ3rOPO
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Mashup Score: 0Molecular profiling identifies targeted therapy opportunities in pediatric solid cancer - Nature Medicine - 3 year(s) ago
An interim report from the GAIN/iCat2 study shows that molecular profiling of pediatric solid malignancies clarifies diagnostic classifications and provides opportunities for matched targeted therapy.
Source: NatureCategories: Hem/Oncs, Latest HeadlinesTweet-
86% of pediatric cancer patients w extracranial solid tumors have genomic alterations that potentially impact clinical care. Important somatic sequencing results from the GAIN/iCAT2 study.Beautiful work @AlannaChurch_MD @janeway_MD @JanewayLab et al. https://t.co/90JJpGpBnu https://t.co/9Ix2E6eWkT
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Mashup Score: 5
PURPOSE To examine the prevalence and dynamics of circulating tumor DNA (ctDNA) and its association with metastatic recurrence in patients with high-risk early-stage hormone receptor–positive breast cancer (HR+ BC) more than 5 years from diagnosis. METHODS We enrolled 103 patients with high-risk stage II-III HR+ BC diagnosed more than 5 years prior without clinical evidence of recurrence. We…
Source: Journal of Clinical OncologyCategories: Latest Headlines, Oncologists1Tweet-
Beautiful work @MarlaLipsycMD et al. on circulating tumor DNA & late recurrence in high risk breast cancer https://t.co/l3MTP5jNPo @DanaFarber https://t.co/rrmGdPGPSn
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Mashup Score: 0Implementing universal upfront multi-gene panel testing in endometrial cancer: From cost to practical considerations - PubMed - 3 year(s) ago
The use of universal upfront MGPT is a practical consideration for patients with newly diagnosed EC for cost savings and improved diagnosis of highly penetrant cancer syndromes. Incorporation of germline genetic testing in the upfront setting represents an opportunity to improve access to genetic co …
Source: PubMedCategories: Hem/Oncs, Latest HeadlinesTweet-
Implementing universal upfront multi-gene panel testing in endometrial cancer: From cost to practical considerations @HHampel1 https://t.co/ZxWhAJf6yf
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Mashup Score: 0
The Geriatric Assessment (GA) is the standard of care for older adults with cancer, but it is not being routinely used. Why not?
Source: JCO Oncology PracticeCategories: Hem/Oncs, Latest HeadlinesTweet-
Why Is Geriatric Assessment so Infrequently Used in Oncology Practices? Great article by @WilliamDale_MD https://t.co/wBUytm7GTs
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Mashup Score: 0The Use and Knowledge of Validated Geriatric Assessment Instruments Among US Community Oncologists - 3 year(s) ago
PURPOSE: The use of a standardized geriatric assessment (GA) to inform treatment decisions in older adults with cancer improves quality of life, reduces treatment-related toxicity, and is guideline-recommended. This study aimed to assess community oncologists’ knowledge and utilization of GAs. METHODS: Between September 2019 and February 2020, practicing US-based oncologists were invited to…
Source: JCO Oncology PracticeCategories: Hem/Oncs, Latest HeadlinesTweet-
The Use and Knowledge of Validated Geriatric Assessment Instruments Among US Community Oncologists https://t.co/OhCyXILqs3
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Mashup Score: 1
PURPOSE: Up to 10% of cancers may be associated with an inherited mutation that increases cancer risk. National guidelines emphasize referral for genetic counseling and testing for patients whose personal and/or family history increases their risk of having a hereditary cancer syndrome. METHODS: To increase appropriate referrals for cancer genetic counseling and testing, we piloted an automated…
Source: JCO Oncology PracticeCategories: Hem/Oncs, Latest HeadlinesTweet-
Can Automated Alerts in the Electronic Health Record Encourage Referrals for Genetic Counseling and Testing Among Patients at High Risk for Hereditary Cancer Syndromes? https://t.co/CuRKrc3NOo
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Mashup Score: 0
Original Article from The New England Journal of Medicine — Adagrasib in Non–Small-Cell Lung Cancer Harboring a KRASG12C Mutation
Source: New England Journal of MedicineCategories: Hem/Oncs, Latest HeadlinesTweet-
Adagrasib in Non–Small-Cell Lung Cancer Harboring a KRASG12C Mutation | NEJM https://t.co/VxOhXKrafD
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Closing the Gap in Cancer Genomic Testing | NEJM https://t.co/Y1D9kvzBsK