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    • Mashup Score: 35
      Composition, Treatment, and Outcomes by Radiologically Defined Thrombus Characteristics in Acute Ischemic Stroke | Stroke - 26 day(s) ago

      Occlusive and nonocclusive cervicocephalic thrombi can be encountered during neurovascular imaging in patients with acute ischemic stroke. Radiographic and morphological characteristics on basic and advanced imaging modalities can be important clues towards determination of pathomechanism and the choice of acute and subacute treatment modalities. The aim of this review article is to evaluate the epidemiology, radiographic properties, histologic clot composition of cervicocephalic arterial thrombi, and its response to various medical and endovascular therapy modalities. Future studies are needed to derive and validate a classification system for extracranial and intracranial partially occlusive thrombi to enable further testing of various stroke treatment and prevention strategies in these patients. Graphical Abstract

      Source: www.ahajournals.org
      Categories: General Medicine News, Neurology
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      • Profile photo of 	ShadiYaghi2
        ShadiYaghi2

        My practice is to use heparin when safe and repeat imaging in ~48 hours then transition to a DOAC, VKA, or LMWH for a short period then AP. It is also reasonable to use DAPT. Check out this review to learn more about this topic: https://t.co/25Vsr6qfKG

    • Mashup Score: 11
      The world’s 20 best cities for food right now - 2 month(s) ago

      We asked thousands of locals to rate their city’s food scene – these are the results.

      Source: www.timeout.com
      Categories: General Medicine News, Neurology
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      • Profile photo of 	ShadiYaghi2
        ShadiYaghi2

        RT @bijoymenon: ISC2026 is at New Orleans! Enjoy the best stroke science at the best city in the world for food! https://t.co/jEpu1KobbS @A…

    • Mashup Score: 0
      Dr. Glaucomflecken (@docglauc) • Instagram reel - 3 month(s) ago

      12K likes, 185 comments – docglauc on February 7, 2025: “The med student faces his greatest challenge”.

      Source: www.instagram.com
      Categories: General Medicine News, Neurology
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      • Profile photo of 	ShadiYaghi2
        ShadiYaghi2

        The standardized neuro-exam 😂 #stroke #neurotwitter https://t.co/OwCTTpH5yr

    • Mashup Score: 208
      Anticoagulation vs Antiplatelets Across Subgroups of Embolic Stroke of Undetermined Source | Neurology - 4 month(s) ago

      Background and ObjectivesThe term “embolic stroke of undetermined source” (ESUS) encompasses a substantial but heterogeneous population of patients with ischemic stroke, underscoring the importance of identifying personalized treatment strategies. In …

      Source: www.neurology.org
      Categories: General Medicine News, Neurology
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      • Profile photo of 	ShadiYaghi2
        ShadiYaghi2

        Is anticoagulation superior in of the ESUS subgroups? #stroke #esus #meded Check out this meta-analysis of randomized controlled trials of ESUS patients investigating the efficacy of anticoagulation compared to antiplatelets based on various mechanisms. https://t.co/QXs4RyP95M https://t.co/7luucpyGjL

    • Mashup Score: 73
      Emergent Carotid Stenting During Thrombectomy in Tandem Occlusions Secondary to Dissection: A STOP-CAD Secondary Study | Stroke - 4 month(s) ago

      Background: The optimal endovascular management of cervical carotid dissection causing tandem occlusion remains uncertain. We investigated the impact of emergent carotid stenting during endovascular treatment (EVT) for acute ischemic stroke (AIS) in patients with tandem occlusion secondary to cervical carotid artery dissection. Methods: This was a secondary analysis of patients treated with EVT for AIS due to occlusive carotid artery dissection and tandem occlusion included in the retrospective international Antithrombotic Treatment for Stroke Prevention in Cervical Artery Dissection (STOP-CAD) study. We compared patients with and without emergent stenting. The primary efficacy and safety outcomes were 90-day functional independence (modified Rankin Scale 0-2) and symptomatic intracranial hemorrhage (sICH) within 24h after EVT. Procedural outcome was successful intracranial recanalization (mTICI 2b/3). We used mixed-effect logistic regression adjusting for site, age, and NIHSS. In addi

      Source: www.ahajournals.org
      Categories: General Medicine News, Neurology
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      • Profile photo of 	ShadiYaghi2
        ShadiYaghi2

        🛑CAD analysis: Should tandem lesions in the setting of dissection be stented? Here is a secondary analysis of the STOP-CAD study showing increased odds of any ICH but sICH but improved reperfusion with stenting and NO difference in mRS at 90 days. https://t.co/wwwH6Evvp2

    • Mashup Score: 69
      Emergent Carotid Stenting During Thrombectomy in Tandem Occlusions Secondary to Dissection: A STOP-CAD Secondary Study | Stroke - 4 month(s) ago

      Background: The optimal endovascular management of cervical carotid dissection causing tandem occlusion remains uncertain. We investigated the impact of emergent carotid stenting during endovascular treatment (EVT) for acute ischemic stroke (AIS) in patients with tandem occlusion secondary to cervical carotid artery dissection. Methods: This was a secondary analysis of patients treated with EVT for AIS due to occlusive carotid artery dissection and tandem occlusion included in the retrospective international Antithrombotic Treatment for Stroke Prevention in Cervical Artery Dissection (STOP-CAD) study. We compared patients with and without emergent stenting. The primary efficacy and safety outcomes were 90-day functional independence (modified Rankin Scale 0-2) and symptomatic intracranial hemorrhage (sICH) within 24h after EVT. Procedural outcome was successful intracranial recanalization (mTICI 2b/3). We used mixed-effect logistic regression adjusting for site, age, and NIHSS. In addi

      Source: www.ahajournals.org
      Categories: General Medicine News, Neurology
      Tweet Tweets with this article
      • Profile photo of 	ShadiYaghi2
        ShadiYaghi2

        🛑CAD analysis: Should tandem lesions in the setting of dissection be stented? Here is a secondary analysis of the STOP-CAD study showing increased odds of any ICH but sICH but improved reperfusion with stenting and NO difference in mRS at 90 days. https://t.co/wwwH6Evvp2

    • Mashup Score: 80
      Endovascular Thrombectomy for Extracranial Internal Carotid Artery Occlusions With Large Ischemic Strokes | Neurology - 4 month(s) ago

      Background and ObjectivesAlthough previous trials have established the efficacy and safety of endovascular thrombectomy (EVT) in large ischemic core strokes, most of them excluded patients with extracranial internal carotid artery (e-ICA) occlusion. We …

      Source: www.neurology.org
      Categories: General Medicine News, Neurology
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      • Profile photo of 	ShadiYaghi2
        ShadiYaghi2

        Let’s admire the power of mechanical thrombectomy in stroke patients seen in this analysis from SELECT-2. Only 62 patients were included with large core & tandem lesions ASPECTS 3-5: OR 4.5 for independent ambulation & 2.5 for mRS, p<0.05. @amrsarrajMD https://t.co/UXWIH8AW3h

    • Mashup Score: 26
      Diagnostic Performance of Carotid Ring Sign on CT-Angiography in Internal Carotid True Occlusion | Stroke - 4 month(s) ago

      BACKGROUND: To differentiate between pseudo occlusion (PO) and true occlusion (TO) of internal carotid artery (ICA) is important in thrombectomy treatment planning for patients with acute ischemic stroke. Although delayed contrast filling has been differentiated carotid PO from TO, its application has been limited by the implementations of multiphasic computed tomography angiography. In this study, we hypothesized that carotid ring sign, which is readily acquired from single-phasic CTA, can sufficiently differentiate carotid TO from PO. METHODS: One thousand four hundred and twenty patients with anterior circulation stroke receiving endovascular therapy were consecutively recruited through a hospital- and web-based registry. Two hundred patients with nonvisualization of the proximal ICA were included in the analysis after a retrospective screening. Diagnosis of PO or TO of the cervical segment of ICA was made based on digital subtraction angiography. Diagnostic performances of carotid

      Source: www.ahajournals.org
      Categories: General Medicine News, Neurology
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      • Profile photo of 	ShadiYaghi2
        ShadiYaghi2

        1. Evidence of a carotid ring sign which is enhancement of the vessel wall suggesting an acute cervical carotid occlusion. Images below show it in red arrows. https://t.co/JjKucqeqw0. https://t.co/b0xBuOcZuX

    • Mashup Score: 8
      Minor ischemic stroke | Neurology Clinical Practice - 4 month(s) ago

      AbstractBackground:Two-thirds of patients with stroke have mild deficits. The optimal triaging of these patients remains unclear. It is crucial to stratify patients based on who needs inpatient vs outpatient evaluation in a cost-effective manner.Methods:…

      Source: www.neurology.org
      Categories: General Medicine News, Neurology
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      • Profile photo of 	ShadiYaghi2
        ShadiYaghi2

        However, studies have shown that “minor” stroke (NIHSS 0-5) is not so minor!!! 1/3 are dead or disabled at 90 days, 1/3 are not ambulatory at discharge, and 1/3 are not discharged home. https://t.co/2AUAlJu5MZ

    • Mashup Score: 2
      Vancouver Stroke Program (@vancouverstroke.bsky.social) - 6 month(s) ago

      www.vancouverstrokeprogram.com

      Source: bsky.app
      Categories: General Medicine News, Neurology
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      • Profile photo of 	ShadiYaghi2
        ShadiYaghi2

        RT @VancouverStroke: In case you are migrating or still going back and forth - we are https://t.co/NMfALR3hsv. @NguyenThanhMD @ShadiYaghi2…

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    Shadi Yaghi

    @ShadiYaghi2

    Vascular Neurologist, cardioneurologist, and Researcher at NYU Langone Health. Tweets = personal opinion, not for clinical advice, RT not endorsement

    ASCO 2025

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