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Mashup Score: 7Anthracyclines-induced cardiotoxicity in patients with early breast cancer carrying germline BRCA1/2 mutation: the BRCAN study - 2 day(s) ago
AbstractBackground. BRCA1/2 genes play a critical role in genome stability and DNA repair. In animal models, loss of cardiomyocyte-specific BRCA1/2 is asso
Source: academic.oup.comCategories: General Medicine NewsTweet
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Mashup Score: 5Breast cancer incidence and mortality, by age, stage and molecular subtypes, by race/ethnicity in Canada - 4 day(s) ago
This article focuses on whether breast cancer characteristics and outcomes differ by race and ethnicity in Canada.
Source: academic.oup.comCategories: General Medicine NewsTweet-
'@anwilkinson and @JeanSeely working with @StatCan_eng show women of racial and ethnic groups other than White are diagnosed with breast cancer at younger ages and more advanced stages. https://t.co/GApIwkoMAG https://t.co/6HQzF44HsR
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Mashup Score: 14
The development of immune-related adverse events (irAEs) has been associated with improved survival outcomes in non-small cell lung cancer (NSCLC). This st
Source: academic.oup.comCategories: General Medicine NewsTweet-
Study finds irAEs in NSCLC patients linked to better survival outcomes regardless of race. Insights into diverse patient responses crucial for personalized care. #NSCLC #immunotherapy #healthdisparities @amrradwan05 @Jani_Chinmay @umittapan_LC_MD https://t.co/S85E8IfHuR https://t.co/5DJ5UpQvuN
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Mashup Score: 2
This study focused on a prospective cost analysis conducted at a high-specialty health facility to assess the economic implications of implementing a risk-
Source: academic.oup.comCategories: General Medicine NewsTweet-
Risk-sharing agreement (RSA) study reveals that RSAs alleviate financial burden of immunotherapy, fostering a more sustainable healthcare model with up to 40% cost reduction. @ogarrieta https://t.co/odi4UejJ4w https://t.co/9CE0uRsjrt
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Mashup Score: 0Opioid use and adverse health effects in breast cancer survivors - 14 day(s) ago
This study examined opioid use and the risk of falls, fractures, lung problems, and cardiovascular events in breast cancer survivors in the years following
Source: academic.oup.comCategories: General Medicine NewsTweet-
Opioid use and adverse health effects in breast cancer survivors @KPSCalResearch https://t.co/r7UAmF99jl https://t.co/oWKX93UIPt
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Mashup Score: 15Recurrent pancreatic cancer treated with N-803 and PD-L1 t-haNK followed by an EGFR-targeted nanocell drug conjugate - 15 day(s) ago
This article presents a case report for a patient who had received 3 lines of therapy for recurrent metastatic pancreatic cancer and who then underwent com
Source: academic.oup.comCategories: General Medicine NewsTweet-
Complete response to multimodal temporal therapy in adv pancreatic cancer provides proof-of-concept for the Nant Cancer Vaccine: tumor-targeted chemotherapy + IL-15 superagonist Anktiva & natural killer cell immunotherapy to induce immunogenic cell death. https://t.co/lMsxMfUJ3q https://t.co/b73ly3FvBG
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Mashup Score: 3
Abstract. The biological and clinical relevance of gene fusions in melanoma is unknown. Reports and preclinical data have suggested that tumor cells with s
Source: academic.oup.comCategories: General Medicine NewsTweet-
Targeting RAF1 gene fusions with MEK inhibition in metastatic melanoma @DrKaramKhaddour @InscoLab https://t.co/LEr18bBSx6 https://t.co/edCHKEXrVp
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Mashup Score: 5Real-world pan-tumor comprehensive genomic profiling sample adequacy and success rates in tissue and liquid specimens - 22 day(s) ago
Real-world success rate of liquid and tissue-based comprehensive genomic profiling (CGP) is unknown. This study analyzed real-world pan-tumor cohorts that
Source: academic.oup.comCategories: General Medicine NewsTweet-
Benchmark study evaluating adequacy and success rates of comprehensive genomic profiling in tissue and plasma samples in a real-world setting. @DougLinMD https://t.co/W4eImLRYAx
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Mashup Score: 10
This study is the first investigation of intrahepatic T-VEC injection in patients with liver lesions due to metastatic solid tumors or hepatocellular carci
Source: academic.oup.comCategories: General Medicine NewsTweet-
Results of the first real-world study of 1st-line CGD in patients w/ BTC w/ early relapse. Analysis suggests that this group can benefit from CGD in terms of OS, PFS, and ORR, with a good safety profile. @casadei_gardini #Cholangiocarcinoma #Immunotherapy https://t.co/uK0PYPfqyi https://t.co/oJnTBRlfqK
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Mashup Score: 4Frequency and outcomes of BRAF alterations identified by liquid biopsy in metastatic, non-colorectal gastrointestinal cancers - 1 month(s) ago
AbstractBackground. Impact of BRAF V600E mutations (BRAFV600E), a poor prognostic factor in metastatic colorectal cancer, is lacking in non-CRC gastrointes
Source: academic.oup.comCategories: General Medicine NewsTweet-
'@Amitmahipal79 et al describe BRAF mut 🎯4.4% of non #crcsm #GIonc cancers, #BRAFV600E most common #hpbcsm. 🩸Liquid biopsy reliably detects‼️ #BRAF status showed mixed #OS, and use of BRAF inhibitors ⬇️ despite approvals. '@doctorC369 https://t.co/ABudX9Kl8r https://t.co/OQA3DLPopu
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#BRCA 1/2 mutation carriers could represent a higher-risk population for anthracyclines-induced #cardiotoxicity in patients with HER2-negative early breast cancer. #CardioOnc #BreastCancer #CardioTwitter #BRCAN https://t.co/fc7CE1dVFR https://t.co/Ct7WaPAPXV