• Mashup Score: 2
    Alvarado score - 3 day(s) ago

    The Alvarado score is a 10 point score for predicting acute appendicitis (mnemonic MANTRELS). Alfredo Alvarado in 1986

    Tweet Tweets with this article
    • Alvarado score • LITFL • Medical Eponym Library https://t.co/ivySvkaPzv

  • Mashup Score: 0

    Background The Alvarado score can be used to stratify patients with symptoms of suspected appendicitis; the validity of the score in certain patient groups and at different cut points is still unclear. The aim of this study was to assess the discrimination (diagnostic accuracy) and calibration performance of the Alvarado score. Methods A systematic search of validation studies in Medline, Embase, DARE and The Cochrane library was performed up to April 2011. We assessed the diagnostic accuracy of the score at the two cut-off points: score of 5 (1 to 4 vs. 5 to 10) and score of 7 (1 to 6 vs. 7 to 10). Calibration was analysed across low (1 to 4), intermediate (5 to 6) and high (7 to 10) risk strata. The analysis focused on three sub-groups: men, women and children. Results Forty-two studies were included in the review. In terms of diagnostic accuracy, the cut-point of 5 was good at ‘ruling out’ admission for appendicitis (sensitivity 99% overall, 96% men, 99% woman, 99% children). At the

    Tweet Tweets with this article
    • The Alvarado score for predicting acute appendicitis: a systematic review | BMC Medicine | Full Text https://t.co/ZUs8jbawcN

  • Mashup Score: 476
    Thomas (@rx) on X - 4 day(s) ago

    working at the intersection between tech and two wheeled things

    Tweet Tweets with this article
    • RT @farmacotips: TRATAMIENTO de ENFEMERDADES de TRANSMISION SEXUAL en ADULTOS 🫵🏼 Comenta ATB para enseñarte antibióticos 👇🏼 https://t.co/r…

  • Mashup Score: 2

    Under recognition combined with suboptimal management of right ventricular (RV) dysfunction and failure is associated with significant perioperative morbidity and mortality. The contemporary perioperative team must be prepared with an approach for early recognition and prompt treatment. In this review, a consensus-proposed scoring system is described to provide a pragmatic approach for expeditious decision-making for these complex patients with a vulnerable RV. Importantly, this proposed scoring system incorporates the context of the planned surgical intervention. Further, as the operating room (OR) represents a unique environment where patients are susceptible to numerous insults, a practical approach to anesthetic management and monitoring both in the OR and in the intensive care unit is detailed. Lastly, an escalating approach to the management of RV failure and options for mechanical circulatory support is provided.

    Tweet Tweets with this article
    • Perioperative management of the vulnerable and failing right ventricle | Perioperative Medicine | Full Text https://t.co/WnpZ0REmPo

  • Mashup Score: 1

    Background The right ventricle (RV) plays a central role in the maintenance of effective cardiac pump function. Despite overwhelming evidence that perioperative RV dysfunction (RVD) and failure (RVF) are associated with poor clinical outcomes, there are very few published recommendations or guidelines for comprehensive, evidence-based RV assessment on the risk of developing either during the perioperative period. Main text To address this gap, the Perioperative Quality Initiative-IX (POQI-IX) investigators group, comprised of clinical experts in anesthesiology, cardiovascular surgery, internal medicine, critical care medicine, and advanced practice nursing, has developed a consensus statement based on current literature, published society recommendations, and the clinical expertise of the group. Herein, the group provides recommendations and evidence-based tools related to perioperative RV assessment, functional screening, staging, and the clinical implications of each. These assessmen

    Tweet Tweets with this article
    • Perioperative Quality Initiative (POQI) consensus statement on perioperative assessment of right ventricular function | Perioperative Medicine | Full Text https://t.co/zB9RjCE7by

  • Mashup Score: 0

    In the United States and other high-income countries, blood donation primarily relies on anonymous, voluntary donors. However, directed blood donation—where people donate for a specific recipient—has resurged, particularly due to misinformation surrounding COVID-19 vaccination. Requests for “nonvaccinated” blood, driven by misconceptions about vaccine safety, have led to legislative attempts to mandate compliance. Historically, directed donation was used to mitigate the risk for transfusion-related infections before modern screening techniques rendered it largely unnecessary. Today, it presents important patient safety risks, including increased infectious disease transmission, immunologic complications, and logistic burdens. Directed donations also introduce inefficiencies, diverting resources from the community blood supply and exacerbating shortages. Moreover, directed donation for nonmedical indications lacks scientific justification. Blood safety is ensured through rigorous donor

    Tweet Tweets with this article
    • Medical, Societal, and Ethical Considerations for Directed Blood Donation in 2025 | Annals of Internal Medicine https://t.co/f6FY7OHjZd

  • Mashup Score: 476
    Thomas (@rx) on X - 7 day(s) ago

    working at the intersection between tech and two wheeled things

    Tweet Tweets with this article
    • RT @farmacotips: TRATAMIENTO de ENFEMERDADES de TRANSMISION SEXUAL en ADULTOS 🫵🏼 Comenta ATB para enseñarte antibióticos 👇🏼 https://t.co/r…