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Mashup Score: 17Dasatinib and CAR T-Cell Therapy in Newly Diagnosed Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia - 24 hour(s) ago
This nonrandomized clinical trial examines the efficacy and safety of dasatinib in combination with chimeric antigen receptor T cells as frontline therapy in adults with newly diagnosed Philadelphia chromosome–positive acute lymphoblastic leukemia.
Source: jamanetwork.comCategories: General Medicine NewsTweet
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Mashup Score: 64Atezolizumab and Trastuzumab Plus Chemotherapy for ERBB2-Positive Locally Advanced Resectable Gastric Cancer - 2 day(s) ago
This randomized clinical trial compares the efficacy and safety of atezolizumab plus trastuzumab plus capecitabine and oxaliplatin chemotherapy (XELOX) vs trastuzumab plus XELOX in Chinese patients with locally advanced human epidermal growth factor receptor 2 (ERBB2)–positive gastric cancer or…
Source: jamanetwork.comCategories: General Medicine NewsTweet-
Adding atezolizumab to trastuzumab and XELOX chemotherapy increased the pathological complete response rate in patients with locally advanced ERBB2-positive gastric or gastroesophageal junction cancer. https://t.co/17WkaYeDDi
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Mashup Score: 5
This randomized clinical trial evaluates the efficacy of sharing follow-up care between the specialty center and a local oncology practice after allogeneic hematopoietic cell transplantation.
Source: jamanetwork.comCategories: General Medicine NewsTweet-
Shared care with local oncologists has the potential to become a routine model for follow-up care after allogeneic hematopoietic cell transplantation. https://t.co/AbHe36hR3W
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Mashup Score: 61
This nonrandomized trial examines 5-year efficacy outcomes evaluating radiotherapy alone without breast surgery in patients with breast cancer selected with image-guided vacuum assisted biopsy.
Source: jamanetwork.comCategories: General Medicine NewsTweet-
Most viewed in the last 7 days from @JAMAOnc: For select breast cancer patients with complete response to neoadjuvant systemic therapy, radiotherapy alone without breast surgery may be feasible, as no tumor recurrences were observed at 5-year follow-up. https://t.co/Tnb8KYXB5h https://t.co/nUFwdh2MRJ
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Mashup Score: 11
Current up-front therapeutic approaches for classic Hodgkin lymphoma (cHL) in children and young adults aim to reduce treatment intensity to minimize long-term treatment-related morbidity. This strategy assumes that patients who relapse can still achieve durable remission with a combination of…
Source: jamanetwork.comCategories: General Medicine NewsTweet-
Editorial: Children and young adults with low-risk relapsed Hodgkin lymphoma can achieve durable remission without high-dose chemotherapy and autologous stem cell transplant. https://t.co/2aIuSSk2Y3
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Mashup Score: 17Transplant and Nontransplant Salvage Therapy in Pediatric Relapsed or Refractory Hodgkin Lymphoma - 6 day(s) ago
This nonrandomized clinical trial in pediatric relapsed classic Hodgkin lymphoma tested fludeoxyglucose-18 positron emission tomography scans to identify patients in whom transplant-free salvage therapy would achieve favorable outcomes.
Source: jamanetwork.comCategories: General Medicine NewsTweet-
Fludeoxyglucose-18-PET response-guided salvage in relapsed classic Hodgkin lymphoma may identify patients in whom transplant-free salvage achieves excellent outcomes. https://t.co/TY6SlCGpSK
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Mashup Score: 38Transplant-Free Approach in Relapsed Hodgkin Lymphoma in Children, Adolescents, and Young Adults - 6 day(s) ago
This nonrandomized clinical trial evaluates a risk-stratified, response-adapted, transplant-free approach for treatment of children, adolescents, and young adults with low-risk relapsed classic Hodgkin lymphoma with nivolumab plus brentuximab vedotin followed by brentuximab vedotin plus bendamustine…
Source: jamanetwork.comCategories: General Medicine NewsTweet-
Transplant-free treatment approach using nivolumab plus BV and ISRT consolidation yielded high complete metabolic response and event-free survival rates in children, adolescents, and young adults with low-risk relapsed classic Hodgkin lymphoma. https://t.co/yNjyh359yc
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Mashup Score: 6Unintended Consequences of Patient Portal Access - 7 day(s) ago
This Viewpoint discusses the unintended consequences of the 21st Century Cures Act for patients and clinicians.
Source: jamanetwork.comCategories: General Medicine NewsTweet-
Viewpoint: The 21st Century Cures Act, which mandates real-time patient access to health data, aims to empower patients but has led to confusion, anxiety, and increased administrative burdens for clinicians. https://t.co/dKHBjfhEEo
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Mashup Score: 123
This nonrandomized trial examines 5-year efficacy outcomes evaluating radiotherapy alone without breast surgery in patients with breast cancer selected with image-guided vacuum assisted biopsy.
Source: jamanetwork.comCategories: General Medicine NewsTweet-
Most viewed in the last 7 days from @JAMAOnc: For select breast cancer patients with complete response to neoadjuvant systemic therapy, radiotherapy alone without breast surgery may be feasible, as no tumor recurrences were observed at 5-year follow-up. https://t.co/qUql8NQwWB https://t.co/Ba1ufBgwhH
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Mashup Score: 20
This pan-cancer ecological study uses the most recent available national health system metrics for cancer outcomes and health system metrics spanning global income levels across 185 countries to examine predictors of improved cancer outcomes.
Source: jamanetwork.comCategories: General Medicine NewsTweet-
The growing cancer burden may be met by efforts to strengthen the clinical workforce, improve gender equity, increase healthcare resource allocation, and promote universal healthcare coverage. https://t.co/c3HJlhaSae @EChrisDee @erin_feliciano @iyengarpuneeth
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Combining dasatinib with CAR T-cell therapy in newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia patients resulted in high rates of complete molecular remission. https://t.co/XIJJxIVH8s