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Mashup Score: 0Dasatinib and CAR T-Cell Therapy in Newly Diagnosed Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia - 11 day(s) ago
This nonrandomized clinical trial examines the efficacy and safety of dasatinib in combination with chimeric antigen receptor T cells as frontline therapy in adults with newly diagnosed Philadelphia chromosome–positive acute lymphoblastic leukemia.
Source: jamanetwork.comCategories: General Medicine NewsTweet
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Mashup Score: 14Outcomes in Transplant Recipients With Advanced Cancers Receiving Immune Checkpoint Inhibitors - 11 day(s) ago
This systematic review and individual participant data met-analysis assesses the cancer-related and survival outcomes in solid organ transplant recipients with advanced-stage cancer treated with immune checkpoint inhibitors.
Source: jamanetwork.comCategories: General Medicine NewsTweet-
Immune checkpoint inhibitors can improve survival in solid organ transplant recipients with advanced cancers, but survival rates remain limited. #TSANZConf @TSANZ_txsoc https://t.co/L80IACCN4e https://t.co/QlOaLzRHJu
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Mashup Score: 67Formulation-Based Cost Savings With Cabozantinib Capsules - 12 day(s) ago
This Viewpoint asserts that the formulation (tablet vs capsule) and the dosage of cabozantinib can be optimized to reduce toxicities and cost while maintaining efficacy.
Source: jamanetwork.comCategories: General Medicine NewsTweet-
Viewpoint: Cabozantinib capsules are more cost-effective than tablets for treating various cancers, and adopting capsule-based dosing strategies could reduce costs while maintaining efficacy. https://t.co/pt9y9gLulX https://t.co/hKIBnSupKs
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Mashup Score: 230
This Viewpoint discusses the need to optimize screening strategies for prostate cancer, including more widespread use of magnetic resonance imaging (MRI)–targeted screening, to overcome limitations of prostate-specific antigen testing.
Source: jamanetwork.comCategories: General Medicine NewsTweet-
Viewpoint: Prostate cancer screening is shifting toward a more beneficial and less harmful approach by using MRI-targeted strategies, which reduce unnecessary biopsies and overdiagnosis. https://t.co/FsfSs3xmkG @IvoSchootsNL https://t.co/dgn3Lo7mdT
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Mashup Score: 126Early ctDNA and Survival in Metastatic Colorectal Cancer Treated With Immune Checkpoint Inhibitors - 14 day(s) ago
This prespecified secondary analysis of a randomized clinical trial assesses the role of circulating tumor DNA in predicting progression-free and overall survival in patients with deficient mismatch repair/microsatellite instability−high metastatic colorectal cancer treated with immune checkpoint…
Source: jamanetwork.comCategories: General Medicine NewsTweet-
Early variation in circulating tumor DNA (ctDNA) can predict long-term progression-free and overall survival in patients with dMMR/MSI-H metastatic colorectal cancer treated with immune checkpoint inhibitors. https://t.co/uQMxwcyQlN @david_tougeron https://t.co/RBODB5bx4k
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Mashup Score: 66Induction vs Adjuvant Chemoradiotherapy in Patients With High-Risk N2 to N3 Nasopharyngeal Carcinoma - 15 day(s) ago
This randomized clinical trial compares the efficacy and safety of induction-concurrent with concurrent-adjuvant chemotherapy in high-risk N2 to N3 nasopharyngeal carcinoma.
Source: jamanetwork.comCategories: General Medicine NewsTweet-
Induction-concurrent chemotherapy does not significantly improve progression-free survival compared with concurrent-adjuvant chemotherapy in high-risk N2–3 nasopharyngeal carcinoma. https://t.co/hLrK38j3Cx https://t.co/EQMMOZyUKh
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Mashup Score: 15Therapy, Safety, and Logistics of Preoperative vs Postoperative Stereotactic Radiation Therapy - 15 day(s) ago
This randomized clinical trial evaluates preoperative stereotactic radiation therapy logistics and safety profile compared with postoperative stereotactic radiation therapy in patients with brain metastases.
Source: jamanetwork.comCategories: General Medicine NewsTweet-
Preoperative stereotactic radiation therapy (SRT) for resectable brain metastases was found to be safe and reduced the time to treatment completion compared to postoperative SRT. https://t.co/4MezuVOiIG @subhaperni @ca_chung @HTawbi_MD https://t.co/RLlC16oTJB
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Mashup Score: 46Caring for Fasting Patients With Cancer During Ramadan - 19 day(s) ago
This Viewpoint presents considerations and potential patient scenarios to help guide clinicians in optimizing care for patients with cancer who are fasting during Ramadan.
Source: jamanetwork.comCategories: General Medicine NewsTweet-
"Caring for fasting oncology patients during Ramadan requires a thoughtful, individualized approach." This Viewpoint discusses how oncology clinicians can provide culturally sensitive care for Muslim cancer patients fasting during Ramadan. https://t.co/qwmnEe6F1M https://t.co/qsguDHz3Zh
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Mashup Score: 25Cancer Incidence and Trends in US Adults With HIV - 20 day(s) ago
This cohort study estimates age-specific cancer incidence rates among people with HIV in the US using a large sample from population-based data registries.
Source: jamanetwork.comCategories: General Medicine NewsTweet-
Cancer rates among people with HIV have declined for certain types, like non-Hodgkin lymphoma and Kaposi sarcoma, due to improved HIV care, though the risk for other cancers remains largely unchanged. https://t.co/mAh3KgECuM https://t.co/lHurnHve5s
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Mashup Score: 41Long-Term Effectiveness Associated With Fecal Immunochemical Testing for Early-Age Screening - 21 day(s) ago
This cohort study evaluates whether initiating fecal immunochemical test screening at age 40 to 49 years, rather than at the currently recommended age of 50 years, reduces colorectal cancer incidence and mortality.
Source: jamanetwork.comCategories: General Medicine NewsTweet-
Initiating fecal immunochemical test screening for colorectal cancer at ages 40 to 49 leads to reductions in colorectal cancer mortality and incidence. https://t.co/Lx2iZBTL97 https://t.co/emAwXUaoEp
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Combining dasatinib with CAR T-cell therapy in newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia patients resulted in high rates of complete molecular remission. https://t.co/bgPw8bqzdZ https://t.co/sx5LXx8MjM