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Mashup Score: 17Chemokine CCL19 promotes type 2 T cell differentiation and allergic airway inflammation - 1 year(s) ago
Allergic asthma is driven largely by allergen-specific type 2 T helper (Th2) cells, which develop in regional lymph nodes upon the interaction of naïv…
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Mashup Score: 10Remibrutinib demonstrates favorable safety profile and sustained efficacy in chronic spontaneous urticaria over 52 weeks - 1 year(s) ago
Remibrutinib (LOU064), an oral, highly selective Bruton tyrosine kinase inhibitor, offers fast disease control in patients with chronic spontaneous ur…
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Mashup Score: 24
In individuals without symptomatic food allergy, food-specific IgE is considered clinically irrelevant. However, recent studies have suggested that ga…
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Mashup Score: 10Revised Swedish infant feeding guidelines are associated with earlier introduction of allergenic foods - 1 year(s) ago
Randomized controlled trials have demonstrated that early introduction of allergenic foods, such as peanut and egg, can reduce food allergy in high-ri…
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Mashup Score: 14IgE directly affects eosinophil migration in chronic rhinosinusitis with nasal polyps through CCR3 and predicts the efficacy of omalizumab - 1 year(s) ago
Whether IgE affects eosinophil migration in chronic rhinosinusitis with nasal polyps (CRSwNP) remains largely unclear. Moreover, our understanding of …
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Mashup Score: 3Asthma morbidity measures across Black ethnic subgroups - 1 year(s) ago
Black adults are disproportionately affected by asthma and are often considered a homogeneous group in research studies despite cultural and ancestral…
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Mashup Score: 2Untargeted metabolomic profiling in children identifies novel pathways in asthma and atopy - 1 year(s) ago
Asthma and other atopic disorders can present with varying clinical phenotypes marked by differential metabolomic manifestations and enriched biologic…
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Mashup Score: 6Airway wall extracellular matrix changes induced by bronchial thermoplasty in severe asthma - 1 year(s) ago
Airway remodeling is a prominent feature of asthma, which involves increased airway smooth muscle mass and altered extracellular matrix composition. B…
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Mashup Score: 0
Author links open overlay panel Antonio Condino-Neto MD, PhD Disclosure of potential conflict of interest: The author declares no relevant conflicts of interest. There are more references available in the full text version of this
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Mashup Score: 10
Author links open overlay panel Ronnie Voon Shiong Tan MBBS, MRCP, Hnin Wint Wint Aung MBBS, MRCP, Cara Flynn MBChB, MRCP, Neil J. Greening BMedSci (Hons), MBBS, PhD, MRCP, Christopher E. Brightling BSc (Hons), MBBS, FRCP, PhD, FMedSci Supported by the National Institute for Health and Care Research (NIHR), Leicester Biomedical Research Centre. The views expressed are those of the author(s) and not necessarily those of the NIHR or the Department of Health and Social Care. Disclosure of potential conflict
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CCR7 and its chemokine ligand CCL21 are known to play a key role in allergic airway disease. Learn about a novel TH2 cell-inducing function of CCL19. Strategies to block the pathway may help to reduce disease incidence or severity. https://t.co/rtglL2tTAs