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Mashup Score: 3Characterization of autoantibody profiles in clusters of systemic lupus erythematosus using a novel autoantigen discovery technology - 1 month(s) ago
Abstract . Systemic lupus erythematosus (SLE) is a complex systemic autoimmune disease characterized by a wide range of clinical and immunologic manifestat
Source: academic.oup.comCategories: General Medicine NewsTweet
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Mashup Score: 9IRF4-regulated transcriptional and functional heterogeneity of lung-resident CD11b+ cDC2 subsets during influenza virus infection - 1 month(s) ago
The Editors have selected this article as a highlight of the issue.
Source: academic.oup.comCategories: General Medicine NewsTweet-
The last May #TopRead from @ibrahim00034 at @OMRF found 2 lung-resident CD11b+ cDC2 subsets present in naïve mice that elaborated distinct and common functional responses regulated by IRF4 during IAV infection. Learn more: https://t.co/zfqYZO6C3S https://t.co/jy9yJ72BZl
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Mashup Score: 9Cathelicidin-related antimicrobial peptide (CRAMP) is toxic during neonatal murine influenza virus infection - 1 month(s) ago
The Editors have selected this article as a highlight of the issue.
Source: academic.oup.comCategories: General Medicine NewsTweet-
Today’s #TopRead Article in May from @ACareyLab at @DrexelMedicine provides insights on the age-specific role of cathelicidin-related antimicrobial peptide (CRAMP) in influenza viral pathogenesis. Learn more: https://t.co/UXd9OXb4q8 https://t.co/KgEHqjvInV
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Mashup Score: 2Regulation of IL-17A–mediated hypersensitivity by extracellular vesicles and lipid nanoparticles carrying miR-451a - 1 month(s) ago
Abstract. Extracellular vesicles (EVs), including exosomes, mediate intercellular communication by transporting functional molecules between donor cells an
Source: academic.oup.comCategories: General Medicine NewsTweet-
Researchers elucidated the physiological role of miR-451a, an immune regulatory microRNA highly abundant in circulating extracellular vesicles, in the proliferation of γδ T cells. Read how this could lead to therapeutics in immune-related diseases: https://t.co/Co1ASuJyax https://t.co/YPd0oaiUgZ
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Mashup Score: 13Volume 214 Issue 5 | The Journal of Immunology | Oxford Academic - 1 month(s) ago
The JI publishes peer-reviewed manuscripts describing novel findings in all areas of experimental immunology, including both basic and clinical studies.
Source: academic.oup.comCategories: General Medicine NewsTweet-
The May issue of The JI is online now! With a special focus on aging and the immune system, this edition is full of interesting research you do not want to miss. Check it out now: https://t.co/loMp3BHvDV https://t.co/Y1dIpK1NAk
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Mashup Score: 12IL-7Rα signaling in regulatory T cells of adipose tissue is essential for systemic glucose homeostasis - 1 month(s) ago
Abstract. Regulatory T cells (Tregs) mediate tissue homeostasis and repair. The function of the interleukin-7 receptor α (IL-7Rα) in nonlymphoid tissue Tre
Source: academic.oup.comCategories: General Medicine NewsTweet-
#ICYMI: Data revealed a novel role for IL-7 and TSLP in immunometabolism by investigating the significance of IL-7R-alpha signaling in the maintenance of visceral adipose tissue regulatory T cells and glucose homeostasis. Learn more: https://t.co/jWkI1wbqmQ https://t.co/7TTQ85Bh3x
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Mashup Score: 7Zebrafish (Danio rerio) TDP43 negatively regulates PKZ-IRF3–mediated IFN I response - 1 month(s) ago
Abstract. Transactive response DNA binding protein 43 kD (TDP43), encoded by the tardbp gene, is a member of heterogenous nuclear ribonucleoproteins family
Source: academic.oup.comCategories: General Medicine NewsTweet-
Knockdown of TDP43 in zebrafish embryos improved embryo survival upon viral infection and upregulated expression of IFN I, demonstrating that DrTDP43 is a negative regulator of IFN I through the inhibition of the PKZ-IRF3–dependent pathway. Read more: https://t.co/M3v0VH7cy4. https://t.co/tuogBuMiL4
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Mashup Score: 17Peptide selectivity of killer cell immunoglobulin-like receptors differs with allotypic variation in HLA class I - 2 month(s) ago
Abstract. Natural killer (NK) cell activation is regulated by killer cell immunoglobulin-like receptors (KIRs) that recognize human leukocyte antigen (HLA)
Source: academic.oup.comCategories: General Medicine NewsTweet-
#ICYMI: Data demonstrated that allotypic differences in peptide repertoire impact KIR recognition of HLA class I, suggesting that NK Cells have the potential to sense infection induced repertoire perturbations. Read it in The JI: https://t.co/MG9xMk8q1F https://t.co/XdA8D9ui3l
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Mashup Score: 51
Abstract. Endometrial stromal cells acquire a secretory profile associated with endoplasmic reticulum stress (ERS) and unfolded protein response (UPR) rela
Source: academic.oup.comCategories: General Medicine NewsTweet-
Findings suggest that exacerbated stromal endoplasmic reticulum stress can be transmitted to monocytes, altering their differentiation, immune profile, and viability, potentially impairing trophoblast migration. Read about here: https://t.co/SuTP3qgKhN https://t.co/0DiKN65bc0
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Mashup Score: 109
Abstract. Antibodies in human milk protect infants against infections, but currently no assay is described that is able to simultaneously measure all 9 ant
Source: academic.oup.comCategories: General Medicine NewsTweet-
A novel low-volume multiplex immunofluorescence assay was developed to simultaneously measure all nine antibody isotypes and subtypes in human fluids, including breastmilk. Learn more about the method in The JI: https://t.co/auRdIuZgaY https://t.co/st6bW77FEW
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#ICYMI: A study in The JI identified new markers to aid in the clustering and understanding of Systemic lupus erythematosus (SLE) subtypes and provides a rationale for elucidating autoantibody expression in SLE beyond antinuclear antibodies. Learn more: https://t.co/27yvBAi5ee. https://t.co/ccZeFIsj4G