• Mashup Score: 20

    Abstract. Inflammasomes are multiprotein innate immune complexes formed in response to infections, tissue damage, or cellular stress that promote the matur

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    • Data suggest that the NLRP3 inflammasome engages an additional innate immune lytic cell death pathway, PANoptosis, for cell death beyond the early timepoints of innate immune responses, which may lead to new therapeutic targets. Learn more: https://t.co/p93QLH2jux. https://t.co/jJXZZRQdpe

  • Mashup Score: 70

    Abstract. Tissue-resident memory cells contribute to allergen-induced inflammation and airway hyperresponsiveness, but relatively little is known of the ce

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    • In a new #CuttingEdge article, data show that the transcription factor Batf3 promotes the development of CD4+ resident memory T cells and thus contributes to allergic responses to inhaled allergens like #asthma. Learn more in The JI: https://t.co/I0dMOEmyjF. https://t.co/rNKwgxzwdm

  • Mashup Score: 70

    Abstract. Tissue-resident memory cells contribute to allergen-induced inflammation and airway hyperresponsiveness, but relatively little is known of the ce

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    • In a new #CuttingEdge article, data show that the transcription factor Batf3 promotes the development of CD4+ resident memory T cells and thus contributes to allergic responses to inhaled allergens like #asthma. Learn more in The JI: https://t.co/I0dMOEmyjF. https://t.co/rNKwgxzwdm

  • Mashup Score: 2

    This Pillars of Immunology article features the seminal 1987 Nature paper by J.A. Todd, J.I. Bell, and H.O. McDevitt, titled “HLA-DQβ gene contributes to s

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    • May’s Pillars of Immunology article highlights the seminal 1987 Nature paper by J.A. Todd, J.I. Bell, and H.O. McDevitt, which provided a breakthrough in understanding genetic susceptibility to type 1 #diabetes. Read the full commentary in The JI: https://t.co/Oum9MWO9Ge. https://t.co/2al1cKBiKz

  • Mashup Score: 16

    An onslaught of infectious disease events over the last 5 yr has focused international attention on immune aging. Specifically, how does the immune system

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    • A special collection on #aging and the immune system highlights the expanding field of immune aging, featuring an invited commentary from a pioneer in the field and a collection of 5 brief reviews from leaders in aging research. Read the editorial: https://t.co/eJzrfhueFP. https://t.co/nbOzWGee44