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    In this episode, host Shikha Jain, MD, speaks with Nadine Spring, PhD, about the importance of DEI in clinical care, driving positive social change forward and more. Welcome to another exciting episode of Oncology Overdrive 0:14 About Spring 0:20 The interview 1:00 Tell me about the journey that got you to where you are today? 1:18 Can you tell me more about Adtalem Global Education and your role there? 5:11 Why does diversity and equitable representation in clinical trials and care matter? 6:23 What is

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    • In the latest episode of Oncology Overdrive: SpringWell360’s founder Kimberly Richardson talks with host @ShikhaJainMD about the importance of #diversity and #equitablerepresentation in #clinicaltrials. Listen now: https://t.co/LkWvfbWr2b https://t.co/xYYfuD3pxR

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    Fear of nuclear fallout has led to a novel therapeutic approach that could significantly extend the lives of individuals with pancreatic cancer or other gastrointestinal malignancies.A novel method of amifostine delivery, currently administered via IV to protect healthy tissue during radiation treatment, showed promise protecting the duodenum during high-dose radiation treatment for pancreatic

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    • Fear of nuclear fallout has led to a novel therapeutic approach that could extend the lives of individuals with pancreatic cancer or other gastrointestinal malignancies. Healio spoke with @DrJamesTour of @RiceUniversity about data from preclinical models. https://t.co/ctZOOYmWfs

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    A novel approach to tumor-infiltrating lymphocyte therapy yielded higher response rates among patients with metastatic gastrointestinal cancers than prior strategies, according to results of a phase 2 trial.The addition of pembrolizumab (Keytruda, Merck) to tumor-infiltrating lymphocytes (TILs) more than tripled the number of responders, from about 8% to nearly 24%.

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    • “Because we’re attacking the #mutations, we potentially can treat any cancer that has mutations.” Steven A. Rosenberg of @NIH discusses how tumor infiltrating lymphocytes could create responses in patients with metastatic #gastrointestinal cancer. https://t.co/i0jPagJ73J

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    Laws that prohibit clinicians from providing health care services to individuals residing in other states have impacted tens of thousands of Americans with cancer, according to results of a retrospective study.In an investigation of more than 1 million fee-for-service Medicare beneficiaries, approximately 7% traveled across state lines to receive cancer care.

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    • “The U.S. has such strong specialists in medical research. It’s a shame that we don’t act like one country and allow it for all citizens.” @ShannonMacDonMD of @MassGeneralNews spoke with Healio about the importance of changing licensure laws. https://t.co/Hz1VNNLy7b

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    Patients with advanced cancer should be enrolled in early phase clinical trials during favorable points in their disease rather than after exhausting standard-of-care treatments, according to a paper published in JCO Oncology Practice.The authors likened the situation to a pilot trying to right the course of an airplane experiencing mechanical problems. The best time to attempt such a correction

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    • Patients with #cancer should be enrolled in early-phase trials at a time when they can best respond, according to a paper authored by researchers at @UCIrvineHealth and published in @JCOOP_ASCO. https://t.co/OjQG6637X3

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    Integrating structured patient-provider conversations about costs into the shared decision-making model of cancer care may help identify financial toxicity and allow for early intervention, according to a review in JCO Oncology Practice.The prevalence — and consequences — of financial toxicity have become well established in oncology, the paper’s authors noted, but few solutions

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    • Healio spoke with @fumikochino of @MDAndersonNews about a review in @JCOOP_ASCO showing that integrating structured patient-provider conversations about costs into the shared decision-making model of cancer care can identify financial toxicity early. https://t.co/iyJnXiYiAM

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    The American Society for Radiation Oncology has issued its first clinical guideline on the use of radiation therapy to treat adults with anal cancer.ASTRO developed the guideline — published in Practical Radiation Oncology — in cooperation with ASCO and Society of Surgical Oncology.

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    • @ASTRO_org, in collaboration with @ASCO, has issued its first-ever guideline on the treatment of anal cancer, which is relatively rare but on the rise, according to guideline author @MaryFengMD. https://t.co/OwiLUD0CCh

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    Exercise improved erectile dysfunction compared with standard care among men with prostate cancer, according to study results published in JAMA Network Open.Men who are concerned about sexual dysfunction should be offered exercise as a potential rehabilitation strategy after treatment, researchers concluded.

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    • Exercise three days per week appeared to help men with #prostatecancer worried about #sexualdysfunction. Healio spoke with the director of the exercise medicine research institute at @EdithCowanUni about the findings. https://t.co/EsPF5J1FH1

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    A common malaria drug could be repurposed to treat a variety of hematologic cancers and solid tumors, according to early study results.Researchers found pyronaridine disrupts an enzyme critical to cellular division and can cause cancer cell death.

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    • Pyronaridine, a common #malaria drug, has demonstrated cytotoxicity against various cancer cell types, including lymphoma, leukemia, breast cancer, ovarian cancer and more. https://t.co/GDznFKBKUp

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    Cancer mortality gradually declined over the past 2-plus decades, although the rate slowed between 2019 and 2022, according to results of the Annual Report to the Nation on the Status of Cancer.Data also showed cancer incidence among women slowly increased from 2003 to 2021, and it stabilized among men from 2013 to 2021 after about a decade of reduced diagnoses.

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    • The Annual Report to the Nation on the Status of Cancer found cancer mortality in the U.S. continues to decline, but the rates have slowed. Also, #cancer incidence among women is increasing. @NAACCR @theNCI @CDCgov @AmericanCancer @JournalCancer https://t.co/e3Ygmp7JBv