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    • Mashup Score: 26
      HIV prevention drug hailed as a 'breakthrough' gets FDA approval - 23 day(s) ago

      A drug called lenacapavir, administered in two injections a year, offers protection from HIV comparable to daily pills. One looming question: Will it be affordable for lower resource countries?

      Source: www.npr.org
      Categories: General Medicine News, Infectious Disease
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      • Profile photo of 	DrOnyemaOgbuagu
        DrOnyemaOgbuagu

        Yeztugo, a.k.a "yes to go" is new trade name for lenacapavir for HIV PrEP approved today by FDA! Price point $14k per dose, given twice yearly, seems priced to be at par with IM CAB and oral TAF/FTC for PrEP. Generic licences for LMIC access / lower cost. https://t.co/7R7WuiOdtI

    • Mashup Score: 26
      HIV prevention drug hailed as a 'breakthrough' gets FDA approval - 23 day(s) ago

      A drug called lenacapavir, administered in two injections a year, offers protection from HIV comparable to daily pills. One looming question: Will it be affordable for lower resource countries?

      Source: www.npr.org
      Categories: General Medicine News, Infectious Disease
      Tweet Tweets with this article
      • Profile photo of 	DrOnyemaOgbuagu
        DrOnyemaOgbuagu

        Yeztugo, a.k.a "yes to go" is new trade name for lenacapavir for HIV PrEP approved today by FDA! Price point $14k per dose, given twice yearly, seems priced to be at par with IM CAB and oral TAF/FTC for PrEP. Generic licences for LMIC access / lower cost. https://t.co/7R7WuiOdtI

    • Mashup Score: 3
      HIV RNA testing to monitor oral PrEP use does not add clinical value: a real-world cohort study—United States, 2019-2023 - 1 month(s) ago

      Among a real-world cohort of oral PrEP users, HIV RNA testing increased after 2021 the CDC PrEP guideline update. However, RNA testing did not result in ea

      Source: academic.oup.com
      Categories: General Medicine News, Infectious Disease
      Tweet Tweets with this article
      • Profile photo of 	DrOnyemaOgbuagu
        DrOnyemaOgbuagu

        Clear example of when broad ranging recomme dations are made to address rare events...in this case delayed or atypical HIV seroconversions for those using oral or injectable PrEP Study shows time to stop doing viral load tests on everyone using oral PrEP https://t.co/NI5g46hBqD

    • Mashup Score: 2
      Texas measles outbreak nears 100 cases, raising concerns about undetected spread - 5 month(s) ago

      Health officials say a measles outbreak in West Texas is growing because of low vaccine rates and undetected infections.

      Source: www.cbsnews.com
      Categories: General Medicine News, Infectious Disease
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      • Profile photo of 	DrOnyemaOgbuagu
        DrOnyemaOgbuagu

        Measles, a vaccine preventable disease, is spreading in TX and NM. I wonder why? https://t.co/v0cOplnvjw

    • Mashup Score: 4
      Iterum Therapeutics Receives U.S. FDA Approval of ORLYNVAH™ (Oral Sulopenem) for the Treatment of Uncomplicated Urinary Tract Infections - 9 month(s) ago

      ORLYNVAH™ is the first oral penem approved for use in the U.S. and the second FDA-approved treatment for uUTIs in the past two decades –Company to…

      Source: www.globenewswire.com
      Categories: General Medicine News, Infectious Disease
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      • Profile photo of 	DrOnyemaOgbuagu
        DrOnyemaOgbuagu

        An oral carbapenem is FDA approved! Wowzer... https://t.co/xkEVUZnMpy

    • Mashup Score: 2
      An oral antiviral for Ebola disease - 10 month(s) ago

      For those exposed to filovirus, such as Sudan virus and Ebola virus, a new study offers hope

      Source: www.science.org
      Categories: General Medicine News, Infectious Disease
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      • Profile photo of 	DrOnyemaOgbuagu
        DrOnyemaOgbuagu

        @RwandaHealth @nsanzimanasabin @GileadSciences https://t.co/0UJ5cZUxf5

    • Mashup Score: 0
      Crack the Case #2: Crack the Case: Drug-Drug Interactions ***Post-Survey & Application for CME Credit*** - 10 month(s) ago

      Take this survey powered by surveymonkey.com. Create your own surveys for free.

      Source: www.surveymonkey.com
      Categories: General Medicine News, Infectious Disease
      Tweet Tweets with this article
      • Profile photo of 	DrOnyemaOgbuagu
        DrOnyemaOgbuagu

        2/#MedTwitter COVID Outpatient Crack the Case ~ 🗓️Day1️⃣ In partnership w @BonumCE Supported by an edu grant from @Pfizer 🟢Next... 1:🎥Watch video 2:🟡Tune in tomorrow for Day 2️⃣answers 3:🔴Answer post-polls 3:🏆Claim🆓CME👉https://t.co/dCfrQb2Wxr 1⃣st: Tell us who you are

    • Mashup Score: 0
      Crack the Case #2: Crack the Case: Drug-Drug Interactions ***Post-Survey & Application for CME Credit*** - 10 month(s) ago

      Take this survey powered by surveymonkey.com. Create your own surveys for free.

      Source: www.surveymonkey.com
      Categories: General Medicine News, Infectious Disease
      Tweet Tweets with this article
      • Profile photo of 	DrOnyemaOgbuagu
        DrOnyemaOgbuagu

        2/#MedTwitter COVID Outpatient Crack the Case ~ 🗓️Day1️⃣ In partnership w @BonumCE Supported by an edu grant from @Pfizer 🟢Next... 1:🎥Watch video 2:🟡Tune in tomorrow for Day 2️⃣answers 3:🔴Answer post-polls 3:🏆Claim🆓CME👉https://t.co/dCfrQb2Wxr 1⃣st: Tell us who you are

    • Mashup Score: 3
      Analysis of drug-drug interactions in patients with HIV and metabolic syndrome - 10 month(s) ago

      People with HIV (PWH) are living longer directly related to highly effective antiretroviral therapy (ART). However, concurrent with improved longevity is the growing prevalence of metabolic comorbi…

      Source: www.tandfonline.com
      Categories: General Medicine News, Infectious Disease
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      • Profile photo of 	DrOnyemaOgbuagu
        DrOnyemaOgbuagu

        Metabolic syndrome increasingly common among people with HIV. A nice resource for providers... we just published...discusses contemporary ART (including lenacapavir) and their interactions with hypertension, Diabetes, antiobesity, lipid lowering drugs https://t.co/GzO9TSNtaS

    • Mashup Score: 8
      Efficacy and Safety of Long-Acting Subcutaneous Lenacapavir in Heavily Treatment-Experienced People with Multi-Drug Resistant HIV-1: Week 104 Results of a Phase 2/3 Trial - 11 month(s) ago

      In a Phase 2/3 study, treatment with lenacapavir, a long-acting HIV-1 capsid inhibitor, plus an optimized background regimen, was well tolerated and result

      Source: academic.oup.com
      Categories: General Medicine News, Infectious Disease
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      • Profile photo of 	DrOnyemaOgbuagu
        DrOnyemaOgbuagu

        Our paper on 2 year efficacy and safety data for lenacapavir for people with multidrug resistant HIV, were viremic and had limited treatment options now published Bottom line...remarkable virologic suppression rates persist and well tolerated. https://t.co/nSuhu8izdW

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    Onyema Ogbuagu

    @DrOnyemaOgbuagu

    Infectious diseases MD, Associate Professor, Yale University. I love conducting clinical trials for treatment or prevention of stubborn viruses!

    ASCO 2025

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