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    The idiopathic inflammatory myopathies represent a rare group of diseases characterized by autoimmune inflammation of skeletal muscle and other organs…

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    • Our latest review article on Idiopathic Inflammatory Myopathy published in Medicine. This is a free link to the full manuscript: https://t.co/0tH5zNeYK1 @NEANU_2021 @sciencedirect @UoMMskResearch @NCAresearchNHS

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    • Taking plunge to run 1st ever marathon at 48yrs! Had to be @LondonMarathon. Running on behalf of @UKMyositis and the patients/carers/fundraisers who help make our @UoMMskResearch a reality. Read about my progress with the option to donate a few pennies https://t.co/N8YfARvgrS

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    Skeletal muscle channelopathies are a group of rare episodic genetic disorders comprising the periodic paralyses and the non-dystrophic myotonias. They may cause significant morbidity, limit vocational opportunities, be socially embarrassing, and sometimes are associated with sudden cardiac death. The diagnosis is often hampered by symptoms that patients may find difficult to describe, a normal…

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    • RT @EmmaM_Channels: Out now online: Skeletal muscle channelopathies: a guide to diagnosis and management https://t.co/FmPar1WCId

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    Megremis, Walker at al. identify immunogenic epitopes in dermatomyositis patients. They identify antibodies recognizing a wider diversity of microbial antigens including poxviruses, and autoantibodies recognizing a large portion of the human proteome. Shared epitope homology between viral and human proteins suggests that molecular mimicry and epitope spreading events may play a role in…

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    • Our latest paper: Human total antibody repertoires in TIF1γ+ dermatomyositis @Akis_BeCool Abs recognizing viruses & Poxviridae species significantly enriched. Molecular mimicry & epitope spreading events important https://t.co/WJouGHsGGO @CommsBio @UoMMskResearch @ManchesterBRC