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Mashup Score: 2Cardiac myosin-specific autoimmune T cells contribute to immune-checkpoint-inhibitor-associated myocarditis - 2 year(s) ago
Immune checkpoint inhibitors (ICIs) are an effective therapy for various cancers; however, they can induce immune-related adverse events (irAEs) as a …
Source: www.sciencedirect.comCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 11PathWays Newsletter | Johns Hopkins Pathology - 2 year(s) ago
PathWays is our annual departmental newsletter. Stay up-to-date on developments, news and people in the Department of Pathology!
Source: pathology.jhu.eduCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 15Cardiovascular Events during World Cup Soccer | NEJM - 2 year(s) ago
Original Article from The New England Journal of Medicine — Cardiovascular Events during World Cup Soccer
Source: New England Journal of MedicineCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 5Cardiac myosin-specific autoimmune T cells contribute to immune-checkpoint-inhibitor-associated myocarditis - 3 year(s) ago
Won et al. demonstrate that PD-1 inhibitor treatment alone induces myocarditis in A/J mice, creating a mouse model for immune-checkpoint-inhibitor-associated myocarditis. Cardiac myosin-specific autoreactive T cells drive the pathogenesis of PD-1 inhibitor-induced myocarditis in mice. PD-1-expressing cardiac myosin-specific T cells are present in the heart during naive conditions.
Source: Cell ReportsCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 6
Trained innate immune responses contribute to pathology of a comorbid condition, as seen with arthritis after periodontitis in animal models.
Source: CellCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 12
Jessica Wade began writing Wikipedia biographies about women and minority scientists who never got their due — from employers, from other scientists, from the public.
Source: TODAY.comCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 10Authors’ names have ‘astonishing’ influence on peer reviewers - 3 year(s) ago
A Nobel prizewinner is six times more likely than someone less well known to get a thumbs-up for acceptance, finds study.
Source: www.nature.comCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 4
The National Heart, Lung, and Blood Institute (NHLBI) convened a workshop of international experts to discuss new research opportunities for the prevention, detection, and intervention of myocarditis in May 2021. These experts reviewed the current state of science and identified key gaps and opportunities in basic, diagnostic, translational, and therapeutic frontiers to guide future research in…
Source: MDPICategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 2Thymic mimetic cells: tolerogenic masqueraders - 3 year(s) ago
SignificanceCenturies-old observations of ‘misplaced’ cells in the thymic medulla have recently been unified in the description of mimetic cells, specialized thymic epithelial cells that appropriate the lineage-defining transcription factors of diverse cell types to express peripheral-tissue antigens within the thymus and tolerize maturing T cells. Defects in mimetic cells may play major roles in…
Source: Trends in ImmunologyCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 6Cantargia reports new positive preclinical efficacy data for CAN10 supporting development in myocarditis - 3 year(s) ago
Cantargia (Cantargia AB; Nasdaq Stockholm: CANTA) today reported new preclinical data from a
Source: News Powered by CisionCategories: Cardiologists, Latest HeadlinesTweet
Our paper https://t.co/aPL6IDnTmd is highlighted in https://t.co/28un632G7t @TaejoonW