• Mashup Score: 5

    Since the first implementation in 2002 by Alain Cribier, transcatheter aortic valve replacement (TAVR) has become a standard procedure for high-risk and elderly patients with severe aortic valve stenosis. Recently, the use of TAVR has expanded to relatively younger patients with low to moderate surgical risk. Infective endocarditis (IE) after TAVR, first reported in medical literature in 2010, is a relatively new and extremely concerning complication.1 Its incidence, reported as 1.1% per person-year based on a large international registry, is similar to that observed in surgical aortic valve replacement (SAVR), despite the latter involving much larger skin incisions and greater internal tissue exposure.2 On the one hand, this fact underscores that the development of IE is influenced not only by the iatrogenic introduction of bacteria but also by the increased risk associated with implanted foreign material. On the other hand, TAVR patients are older, have an increased frailty and an in

    Tweet Tweets with this article
    • Bacteraemia & infective endocarditis after TAVI @Heart_BMJ https://t.co/2N8mf79xFs

  • Mashup Score: 5

    Since the first implementation in 2002 by Alain Cribier, transcatheter aortic valve replacement (TAVR) has become a standard procedure for high-risk and elderly patients with severe aortic valve stenosis. Recently, the use of TAVR has expanded to relatively younger patients with low to moderate surgical risk. Infective endocarditis (IE) after TAVR, first reported in medical literature in 2010, is a relatively new and extremely concerning complication.1 Its incidence, reported as 1.1% per person-year based on a large international registry, is similar to that observed in surgical aortic valve replacement (SAVR), despite the latter involving much larger skin incisions and greater internal tissue exposure.2 On the one hand, this fact underscores that the development of IE is influenced not only by the iatrogenic introduction of bacteria but also by the increased risk associated with implanted foreign material. On the other hand, TAVR patients are older, have an increased frailty and an in

    Tweet Tweets with this article
    • Bacteraemia & infective endocarditis after TAVI @Heart_BMJ https://t.co/2N8mf79xFs

  • Mashup Score: 6

    Objective To assess the three year outcomes of the no-touch vein harvesting technique in coronary artery bypass grafting surgery compared with the conventional approach. Design Three year extended follow-up of the randomised PATENCY (graft patency between the no-touch vein harvesting technique and conventional approach in coronary artery bypass graft surgery) trial. Setting Seven cardiac surgery centres in China; enrolment between April 2017 and June 2019. Participants 2655 participants aged 18 and older undergoing isolated coronary artery bypass grafting surgery. Interventions Patients were randomly assigned 1:1 to the no-touch vein harvesting technique group or the conventional approach group during surgery and followed up. Main outcome measures Vein graft occlusion (based on computed tomography angiography) at three years. Results Mean age of participants was 61 years (standard deviation ±8 years) and 22% were women. 99.4% (2621) attended the three year follow-up visit, while 86.5%

    Tweet Tweets with this article
    • 🚫”Do not touch”… Meticulous preservation of the venous adventitia & perivascular tissue with avoidance of manual distension of the veins reduces the risk of vein graft occlusion at three years. The PATENCY randomised clinical trial ⁦@bmj_latest⁩ https://t.co/VYFRsX1N9v