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Mashup Score: 4
View all available purchase options and get full access to this article. Mark D, Li Y, Nanna M, Kelsey M, Daniels M, Rogers C, Patel M, Baloch K, Chow B, Anstrom K, et al; PRECISE-Investigators. Quality of life outcomes with a risk-based testing strategy versus usual testing in stable patients with suspected coronary disease: Results from the precise randomized trial. Circ Cardiovasc Qual Outcomes. 2024;:e011414. doi: 10.1161/CIRCOUTCOMES.124.011414 Chew DS, Mark DB, Li Y, Nanna MG, Kelsey MD, Daniels
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 8
BACKGROUND: The PRECISE (Prospective Randomized Trial of the Optimal Evaluation of Cardiac Symptoms and Revascularization) trial compared an investigational precision diagnostic testing strategy (n=1057) with usual testing (n=1046) in patients with stable chest pain and suspected coronary artery disease. Quality of life (QOL) outcomes were a prespecified secondary end point. METHODS: We assessed QOL by structured interviews in all trial participants at baseline and 45 days, 6 months, and 12 months postrandomization. QOL assessments included angina-related QOL (19-item Seattle Angina Questionnaire [SAQ-19]), generic health status (EQ-5D), and a 4-item care satisfaction survey (at 45 days only). The prespecified primary comparison was the 6-month SAQ Summary score outcomes (scale, 0 to 100; higher scores indicate greater health status). QOL data collection rates were high, with 99% complete baseline SAQ scores and 86.5% complete at the 6-month primary comparison follow-up. All comparison
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Quality of Life Outcomes with a Risk-Based Precision Testing Strategy Versus Usual Testing in Stable Patients with Suspected Coronary Disease: Results from the PRECISE Randomized Trial @GreggWStone @bchowmd @jweirmccall @derek_c1 @MichaelGNanna @DanMarkMD https://t.co/mghHvTYJn8 https://t.co/pQ1qGReKlk
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Mashup Score: 10
BACKGROUND: The PRECISE (Prospective Randomized Trial of the Optimal Evaluation of Cardiac Symptoms and Revascularization) demonstrated that a precision diagnostic strategy reduced the primary composite of death, nonfatal myocardial infarction, or catheterization without obstructive coronary artery disease by 65% in patients with nonacute chest pain compared with usual testing. Medical cost was a prespecified secondary end point. METHODS: PRECISE randomized 2103 patients between December 2018 and May 2021 to usual testing or a precision strategy that used deferred testing for the lowest risk patients (20%) and coronary computed tomographic angiography with selective computed tomography–derived fractional flow reserve for the remainder. Resource use consumption data were collected from all study participants and hospital cost data from US participants (n=1125) to estimate total medical costs. The primary and secondary economic outcomes were total costs at 12 months and at 45 days, respe
Source: www.ahajournals.orgCategories: General Medicine News, Cardiology News and JournTweet
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Mashup Score: 3
View all available purchase options and get full access to this article. File (circcvqo-2024-011544-s01.pdf) Figures S1 and S2 File (circcvqo-2024-011544-s02.pdf) Request permissions for this article. Department of Internal Medicine, Mayo Clinic, Rochester, MN (C.L.C.). Department of Internal Medicine, Division of Cardiology, University of Texas Southwestern Medical Center, Dallas (S.G., Nimesh Patel, M.K., M.S.S.). Department of Internal Medicine, Division of Palliative Care, UT Southwestern Medical
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Mashup Score: 4
BACKGROUND: Validly measuring disease-specific health status is critical in patients with severe tricuspid regurgitation (TR) to quantify the benefit of different interventions. The Kansas City Cardiomyopathy Questionnaire (KCCQ) has been used to assess health status in patients with severe TR, but its content validity in this patient population is unknown, including whether additional questions are needed to supplement the KCCQ. METHODS: Twenty participants with symptomatic severe TR from 2 midwestern clinical sites were interviewed in 2023 using a semistructured guide. The interview guide addressed symptoms, physical and social functioning, and quality of life concepts of the KCCQ, as well as other potential TR symptoms not represented in the KCCQ. Interview transcripts were analyzed using inductive and deductive coding and content analysis, with additional participants recruited until thematic saturation occurred. RESULTS: Mean age of the participants was 80 (41–89), and 75% were fe
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 4
View all available purchase options and get full access to this article. Mark D, Li Y, Nanna M, Kelsey M, Daniels M, Rogers C, Patel M, Baloch K, Chow B, Anstrom K, et al; PRECISE-Investigators. Quality of life outcomes with a risk-based testing strategy versus usual testing in stable patients with suspected coronary disease: Results from the precise randomized trial. Circ Cardiovasc Qual Outcomes. 2024;:e011414. doi: 10.1161/CIRCOUTCOMES.124.011414 Chew DS, Mark DB, Li Y, Nanna MG, Kelsey MD, Daniels
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 3
BACKGROUND: Increased burden of socially determined vulnerabilities (SDV), which include nonmedical conditions that contribute to patient health, is associated with incident heart failure (HF). Mediators of this association have not been examined. We aimed to determine if a healthy lifestyle mediates the association between SDV and HF. METHODS: We included adults aged 45 to 64 years old across the United States from the REGARDS cohort study (Reasons for Geographic and Racial Differences in Stroke) without evidence of HF at baseline. The primary exposure was a count of SDV based on the Healthy People 2030 framework. The primary outcome was incident HF. We assessed the role of a healthy behavior score (HBS range, 0–8) and its components (adherence to a Mediterranean diet, physical activity, lack of sedentary lifestyle, and smoking abstinence) as potential mediators of the association between SDV and incident HF. RESULTS: We included 13 on 525 participants. The median HBS was 4, with 16%
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Mashup Score: 1
BACKGROUND: The absence of practice standards in vasoactive agent usage for acute decompensated heart failure has resulted in significant treatment variability across hospitals, potentially affecting patient outcomes. This study aimed to assess temporal trends and institutional differences in vasodilator and inotrope/vasopressor utilization among patients with acute decompensated heart failure, considering their clinical phenotypes. METHODS: Data were extracted from a government-funded multicenter registry covering the Tokyo metropolitan area, comprising consecutive patients hospitalized in intensive/cardiovascular care units with a primary diagnosis of acute decompensated heart failure between January 2013 and December 2021. Clinical phenotypes, that is, pulmonary congestion or tissue hypoperfusion, were defined through a comprehensive assessment of clinical signs and symptoms, vital signs, and laboratory findings. We assessed the frequency and temporal trends in phenotype-based drug
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Mashup Score: 1
BACKGROUND: Food insecurity is associated with high morbidity and mortality and is typically measured with the 10-item US Adult Food Security Survey Module. Shorter instruments may capture similar information, but this has not been validated against mortality in general populations. METHODS: A nationally representative sample of individuals aged 20 to 74 years from the US National Health Interview Survey 2011 to 2018 was included, with deaths linked to the National Death Index through 2019. Cardiovascular disease deaths were ascertained by International Classification of Diseases-Tenth Revision codes for heart disease or stroke. Standard 10-, 6-, and 2-item food security instruments were compared for associations with premature all-cause and cardiovascular disease deaths occurring before age 75 years using Cox regression adjusted for demographics and social determinants of health and C statistics. Findings were replicated in the National Health and Nutrition Examination Survey 2004 to
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Mashup Score: 0
BACKGROUND: Although racial disparities have been described in resuscitation, little is known about potential bias in race classification of out-of-hospital cardiac arrest (OHCA). METHODS: We conducted a retrospective cohort study of adults treated by emergency medical services (EMS) for nontraumatic OHCA in King County, WA between January 1, 2018, and December 31, 2021. We assessed agreement using κ and evaluated patterns of missingness between EMS-assessed race versus comprehensive race classification from hospital and death records. Using multivariable logistic regression adjusting for Utstein data elements, we analyzed the association between race and OHCA survival across different sources. RESULTS: Among 5909 eligible OHCA patients, the average age was 64.0 years, 35.4% were female, and 16.1% survived to hospital discharge. Based on comprehensive race classification, 68.7% were White, 12.8% Black, 12.1% Asian, 2.5% multiracial, 2.3% Native Hawaiian/other Pacific Islander, and 1.6%
Source: www.ahajournals.orgCategories: General Medicine News, CardiologistsTweet
Asking a More PRECISE Question? @cardiac_md #AHAJournals https://t.co/tCJMXBprnY