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    • Mashup Score: 0
      Induction of cellular autophagy impairs TGF-β1-mediated extracellular matrix deposition in primary human knee fibroblasts - AI Talks with Bone & Joint - 2 hour(s) ago

      Listen to Lisa and Brian discuss the paper ‘Induction of cellular autophagy impairs TGF-β1-mediated extracellular matrix deposition in primary human knee fibroblasts’ published in the April 2025 issue of Bone & Joint Research.Click here to read the paper.Be the first to know when the next episode is live! Follow our social media accounts, @BoneJointPortal and @BoneJointRes on X, and @bonejointres on Instagram for updates!

      Source: www.buzzsprout.com
      Categories: General Medicine News, Rheumatology
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        BoneJointRes

        🎙️ NEW PODCAST OUT! 🎙️ This week's discussion covers a captivating study that explores how inducing cellular autophagy can affect the extracellular matrix deposition in knee fibroblasts. Check it out today! #BJR #Podcast #OrthoTwitter #KneeArthroplasty https://t.co/AxeqEAkfP0 https://t.co/neKn0amRAk

    • Mashup Score: 10
      Artificial intelligence in orthopaedic surgery | Bone & Joint - 3 hour(s) ago

      Artificial intelligence in orthopaedic surgery

      Source: boneandjoint.org.uk
      Categories: General Medicine News, Rheumatology
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        BoneJointRes

        Existing applications of AI orthopaedic surgery have shown promise highlighting implant malposition; detecting features of loosening; predicting hospital stay, costs, outcomes, & prognostic scores; & implant identification in arthroplasty. #AI #BJR https://t.co/ZzCichpM3Q https://t.co/n6YfhcS9pu

    • Mashup Score: 2
      Evaluation of at-home physiotherapy | Bone & Joint - 2 day(s) ago

      Evaluation of at-home physiotherapy

      Source: boneandjoint.org.uk
      Categories: General Medicine News, Rheumatology
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        BoneJointRes

        The aim of this research was to evaluate performance of machine-learning methodologies for detecting and classifying inertial data collected during in-clinic and at-home shoulder physiotherapy exercise. #Physiotherapy #MachineLearning #Research #BJR https://t.co/lzPWDJUN5g https://t.co/LMKMtRHd9a

    • Mashup Score: 1
      Increasing reaming depth enhances implant stability while minimizing bone strain | Bone & Joint - 17 day(s) ago

      Increasing reaming depth enhances implant stability while minimizing bone strain

      Source: boneandjoint.org.uk
      Categories: General Medicine News, Rheumatology
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      • Profile photo of 	BoneJointRes
        BoneJointRes

        Enhancing cavity reaming depth is a simple technique to increase the implant primary stability of press-fit uncemented acetabular cupsomponents, while avoiding any excess in periacetabular strain and the associated fracture risk. #BJR #Fracture #Surgeon https://t.co/xMniJ78qa2 https://t.co/bO48ni9WXK

    • Mashup Score: 2
      Hederagenin promotes SIRT6 to attenuate epidural scar formation by aggravating PRMT1 deacetylation | Bone & Joint - 19 day(s) ago

      Hederagenin promotes SIRT6 to attenuate epidural scar formation by aggravating PRMT1 deacetylation

      Source: boneandjoint.org.uk
      Categories: General Medicine News, Rheumatology
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        BoneJointRes

        This study aimed to investigate the effect and regulatory mechanism of hederagenin, which is widely present in various medicinal plants, on epidural scar formation. #Biology #Research #OpenAccess #BJR https://t.co/jzMZB6gSVw https://t.co/FDLMIN7cwg

    • Mashup Score: 2
      Single-cell transcriptomics analysis of the healing process of ligament rupture | Bone & Joint - 20 day(s) ago

      Single-cell transcriptomics analysis of the healing process of ligament rupture

      Source: boneandjoint.org.uk
      Categories: General Medicine News, Rheumatology
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        BoneJointRes

        Further analysis of the tenocyte populations revealed ten distinct cell subtypes, highlighting the diversity of tenocytes in human anterior cruciate ligament tissues. #BJR #ACL #Surgery #OrthoTwitter https://t.co/7Op7umhWZ9 https://t.co/8momrcaMr2

    • Mashup Score: 4
      The association between selenium and bone health: a meta-analysis | Bone & Joint - 20 day(s) ago

      The association between selenium and bone health: a meta-analysis

      Source: boneandjoint.org.uk
      Categories: General Medicine News, Rheumatology
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        BoneJointRes

        Compared with those who had lower dietary selenium intake and lower serum selenium, subjects with higher dietary selenium intake and higher serum selenium had higher bone mineral density. #Biology #Research #Fracture #BJR https://t.co/qvhbIxcoCY https://t.co/bwmFeJIxHm

    • Mashup Score: 7
      Cytokines and regulatory T cells in ankylosing spondylitis | Bone & Joint - 21 day(s) ago

      Cytokines and regulatory T cells in ankylosing spondylitis

      Source: boneandjoint.org.uk
      Categories: General Medicine News, Rheumatology
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        BoneJointRes

        This study aimed to investigate the correlations among cytokines and regulatory T cells in ankylosing spondylitis patients, and their changes after anti-tumour necrosis factor-α treatment. #Spine #BJR #Research https://t.co/wkKvrxCTIl https://t.co/7MQ5LWpOay

    • Mashup Score: 2
      Temporal- and concentration-dependent effects of transforming growth factor-beta 1 (TGF-β1) in primary human knee fibroblasts | Bone & Joint - 22 day(s) ago

      Temporal- and concentration-dependent effects of transforming growth factor-beta 1 (TGF-β1) in primary human knee fibroblasts

      Source: boneandjoint.org.uk
      Categories: General Medicine News, Rheumatology
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      • Profile photo of 	BoneJointRes
        BoneJointRes

        While TGF-β1 signalling pathways are well-characterized across many fibrotic diseases, this investigation is the first to elucidate key TGF-β1 experimental dosing & exposure parameters in primary knee fibroblasts derived from TKA patients. #BJR #Knee https://t.co/6DSa5gTSFV https://t.co/ouehRIjC3H

    • Mashup Score: 7
      Don’t mind the gap: reframing the Perren strain rule for fracture healing using insights from virtual mechanical testing | Bone & Joint - 22 day(s) ago

      Don’t mind the gap: reframing the Perren strain rule for fracture healing using insights from virtual mechanical testing

      Source: boneandjoint.org.uk
      Categories: General Medicine News, Rheumatology
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        BoneJointRes

        This ovine study found that high gap strain appears to be a transient local limiter of osteogenesis, not a global inhibitor of secondary fracture repair. #BJR #FractureHealing #OpenAccess @DaileyOrthoLab https://t.co/6fizd9ly7P https://t.co/mgf4DkO430

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    Bone & Joint Research

    @BoneJointRes

    A Gold open access orthopaedics and musculoskeletal research journal edited by Professor Hamish Simpson and published by Bone & Joint. Impact factor: 2.597

    ASCO 2025

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