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Mashup Score: 4
Objective To estimate the impact of standardising the colour and branding of disposable vaping devices on young people’s interest in trying them. Design, setting and participants Data were from national surveys of 16–29-year-olds in Canada, England and the United States in 2023 (N=15 259). Interventions Respondents were randomised (1:1) to view images of either four branded disposable vapes (N=7638) or four standardised white disposable vapes (n=7621) and asked which they would be interested in trying. Main outcome measures The primary outcome was selecting “no interest in trying” rather than any of the vapes displayed. We also examined whether the impact of standardisation differed by five potential moderators. Results A greater proportion of participants reported “no interest in trying” the white standardised than branded vapes (67.1% vs 62.8%; adjusted risk ratio (ARR) 1.127, 95% CI 1.085 to 1.169). Compared with those who had never smoked or vaped, the impact of standardisation on
Source: tobaccocontrol.bmj.comCategories: General Medicine NewsTweet
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Mashup Score: 1Paediatric magnet ingestion persists worldwide despite increasing regulatory policies - 3 day(s) ago
Objective Paediatric magnet ingestion can have devastating consequences. To minimise this risk, many countries have policies to reduce exposure. This study seeks to summarise global reports of paediatric magnet ingestion and stringency of corresponding national policies. Study design A comprehensive literature search was conducted in English and Spanish using PubMed, Google Scholar, Scopus, Virtual Health Library, Clarivate–Web of Science, and Latin American and Caribbean Health Sciences Literature. Included papers documented magnet ingestion in ages 0–18 years, from 2002 to 2024. Non-magnet foreign body ingestions were excluded. Policy searches were conducted online in English and Spanish. In total, 2998 articles were reviewed, with 204 papers undergoing full-text analysis. Data regarding incidence, demographics, and interventions required were extracted. Results A total of 96 studies from countries in six continents documenting patients requiring hospitalisation and/or medical interv
Source: injuryprevention.bmj.comCategories: General Medicine NewsTweet-
Thousands of young children around the world are still swallowing magnets despite tighter regulations, reveals a study in @IP_BMJ https://t.co/UBqlQSt4KD https://t.co/X4XOa7TRAa
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Mashup Score: 2Association between herpes simplex virus type 1 and the risk of Alzheimer’s disease: a retrospective case–control study - 3 day(s) ago
Objective A growing body of evidence points to a role for herpesviruses in the development of Alzheimer’s disease (AD) and a reduced risk of AD among patients receiving antiherpetic medications. We investigated the association between herpes simplex virus type 1 (HSV-1) and AD using real-world data (RWD) from USA. Design In a matched case–control study, patients with AD aged ≥50 years diagnosed between 2006 and 2021 were identified from the IQVIA PharMetrics Plus claims database. Controls were matched in a 1:1 ratio with subjects with AD on age, sex, region, database entry year and healthcare visit numbers. Results The study included 344 628 AD case–control pairs. History of HSV-1 diagnosis was present in 1507 (0.44%) patients with AD compared with 823 (0.24%) controls. HSV-1 diagnosis was found to be associated with AD (adjusted OR 1.80; 95% CI 1.65 to 1.96). Patients with HSV-1 who used antiherpetics were less likely to develop AD compared with those who did not use antiherpetics (ad
Source: bmjopen.bmj.comCategories: General Medicine NewsTweet-
Might cold sores be implicated in a heightened risk of developing Alzheimer's disease? Read a large study in @BMJ_Open to find out. https://t.co/XnBz5fAtVq https://t.co/cG2RQW3tYX
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Mashup Score: 0Impact of physical activity on the incidence of psychiatric conditions during childhood: a longitudinal Swedish birth cohort study - 10 day(s) ago
Background Emerging evidence supports the importance of physical activity (PA) and behaviours that build resilience to prevent childhood psychiatric disorders. Objective To investigate associations between parent-reported PA, time spent outdoors and participation in organised sports and later incidence of psychiatric conditions in children. Methods A birth cohort of 17 055 Swedish children was followed up until age 18 years. Data on parent-reported PA, time outdoors and participation in organised sports were collected for children at ages 5, 8 and 11. Diagnoses of psychiatric conditions were obtained from a national registry. Longitudinal interactions were analysed with two-way analysis of variance, and hazard ratios for incidence until 18 years were calculated with Cox proportional hazard models, adjusting for mothers’ education and use of psychotropics, children’s adverse life events and sex. Results PA declined from 4.2 to 2.5 hours per day between 5 and 11 years of age. PA at 11 ye
Source: bjsm.bmj.comCategories: General Medicine NewsTweet-
A study in @BJSM_BMJ suggests that physical activity, particularly taking part in organised sports may ward off childhood mental ill health. https://t.co/ojvss7TFlr
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Mashup Score: 4Overwork and changes in brain structure: a pilot study - 10 day(s) ago
Objectives To investigate the effects of overwork on brain structure to better understand its impact on workers’ cognitive and emotional health. The goal was to provide evidence for the potential neurological risks associated with prolonged working hours. Methods A total of 110 healthcare workers were classified into overworked (≥52 hours/week; n=32) and non-overworked groups (n=78). Brain volume differences were assessed using voxel-based morphometry (VBM) and atlas-based analysis. General linear models adjusted for age, sex and total intracranial volume were applied, and correlation analyses explored relationships between weekly working hours and brain volume in regions with significant differences. Results Overworked individuals exhibited significant changes in brain regions associated with executive function and emotional regulation. Atlas-based analysis revealed a 19% increase in left caudal middle frontal gyrus volume in the overworked group compared with the non-overworked group
Source: oem.bmj.comCategories: General Medicine NewsTweet-
Preliminary findings in @OEM_BMJ suggest that overwork may induce neuroadaptive changes in the brain that affect cognitive and and emotional health https://t.co/03tdfOyhgK
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Mashup Score: 6Gender, tobacco and chronic obstructive pulmonary disease: analysis of the 2020 National Health Interview Survey - 15 day(s) ago
Rationale Recent studies describe an increasing prevalence of chronic obstructive pulmonary disease (COPD) and higher COPD exacerbation rates among women compared with men despite lower average cigarette use, which has raised the question of whether women are more susceptible to the effects of tobacco smoke. We examined associations between gender, cigarette smoking and COPD in a national dataset.Methods We used cross-sectional data for US respondents aged ≥40 years from the 2020 National Health Interview Survey (NHIS). Weighted multivariable logistic regressions assessed the relationship between gender and respondent-reported physician-diagnosed COPD, adjusting for tobacco use and sociodemographic covariates. Additional analyses were performed to determine if the relationship between cigarette smoking and COPD was modified by gender.Results Women had a higher COPD prevalence (7.8%) than men (6.5%) despite lower cigarette smoke exposure. Women were less likely to have ever smoked, and
Source: bmjopenrespres.bmj.comCategories: General Medicine NewsTweet-
Women are around 50% more likely than men to develop COPD even if they have never smoked or smoked much less than their male counterparts, suggests a study in @BMJOpen_Resp. https://t.co/yB0Mooxh2j
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Mashup Score: 2DOI Not Found | BMJ Open - 15 day(s) ago
No resource with that DOI could be found on this site. Sending you to the original source in 8. You may also click
Source: bmjopen.bmj.comCategories: General Medicine NewsTweet-
A blood test for many different types of cancer could thwart progression while the disease is still at an early stage in up to half of cases, suggests research published in @BMJ_Open. https://t.co/bvrbkJs9Zc https://t.co/hWGe741W7T
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Mashup Score: 6Use of gabapentinoid treatment and the risk of self-harm: population based self-controlled case series study - 23 day(s) ago
Objective To estimate the effect of gabapentinoid treatment on self-harm. Design A population based self-controlled case series study. Setting UK Clinical Practice Research Datalink Aurum database linked to the Hospital Episode Statistics and Office for National Statistics databases. Participants 10 002 adults (aged ≥18 years), with gabapentinoid prescriptions, who had an incident event of self-harm between 1 January 2000 and 31 December 2020. Individual censoring occurred on the date of epilepsy, substance misuse, or cancer diagnosis. Main outcome measures Crude incidence rates of self-harm in different risk periods: 90 days before gabapentinoid treatment, gabapentinoid treatment period, 14 days after treatment periods, and reference periods were calculated. Conditional Poisson regression derived the incidence rate ratio and 95% confidence intervals (CIs) to evaluate the risk of self-harm in different risk periods, compared with reference period for each individual. Results 1 503 597
Source: www.bmj.comCategories: General Medicine NewsTweet-
Gabapentinoids unlikely to be directly linked to self-harm risk, finds a UK study published by @bmj_latest today https://t.co/NFajZmgQSZ
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Mashup Score: 0
Objective To examine the comprehensive health impacts of exercise on people with cancer by systematically summarising existing evidence and assessing the strength and reliability of the associations. Design Umbrella review of meta-analyses. Data source PubMed, Embase, Cochrane and Web of Science databases were searched from their inception to 23 July 2024. Eligibility criteria for selecting studies Meta-analyses of randomised controlled trials that investigated the associations between exercise and health outcomes among people with cancer. Results This umbrella review identified 485 associations from 80 articles, all evaluated as moderate to high quality using A Measurement Tool to Assess Systematic Reviews (AMSTAR). Two hundred and sixty (53.6%) associations were statistically significant (p<0.05), 81/485 (16.7%) were supported by high-certainty evidence according to the Grading of Recommendations Assessment, Development, and Evaluation criteria. Compared with usual care or no exercis
Source: bjsm.bmj.comCategories: General Medicine NewsTweet-
Exercise can counter detrimental effects of cancer treatment suggests a study in @BJSM_BMJ https://t.co/na0E9iaX2P
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Mashup Score: 3DOI Not Found | BMJ Quality & Safety - 24 day(s) ago
No resource with that DOI could be found on this site. Sending you to the original source in 8. You may also click
Source: qualitysafety.bmj.comCategories: General Medicine NewsTweet-
Too few ward nurses linked to longer hospital stay, readmission, and risk of death, finds a study published in @BMJ_Qual_Saf https://t.co/Gb0uc9hcCk
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Standardising disposable vape devices seems to curb young people’s desire to try them, finds a case-control study in @TC_BMJ. But the trade-off is that it may lead to fewer people switching from smoking to vaping, warn the researchers. https://t.co/nwCjoDtFiI https://t.co/VGqJgqNOwv