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Mashup Score: 0Accelerated drug approvals and patient trust: impact of voxelotor and crizanlizumab for sickle cell disease - 1 hour(s) ago
Abstract. Crizanlizumab and voxelotor were several of the first drugs to receive the US Food and Drug Administration (FDA) approval for sickle cell disease
Source: ashpublications.orgCategories: General Medicine NewsTweet
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Mashup Score: 5Implementing ASH’s guidelines for acute medical care for incarcerated children and adults with sickle cell disease - 1 day(s) ago
Abstract. Between 2019 and 2021, the American Society of Hematology (ASH) developed clinical guidelines for managing sickle cell disease (SCD), covering ac
Source: ashpublications.orgCategories: General Medicine NewsTweet-
An absence of a strategy to implement clinical practice guidelines that mandate acute medical care may lead to death or irreversible morbidity. https://t.co/b1Ia1SqbSr #healthserviceandoutcomes #redcellsironanderythropoiesis
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Mashup Score: 18A cure for the kiss of death? - 3 day(s) ago
In this issue of Blood Advances, Lontos1 et al provide a comprehensive report of the survival outcomes among 240 patients who underwent a transplant at the
Source: ashpublications.orgCategories: General Medicine NewsTweet-
a comprehensive report of the survival outcomes among 240 patients who underwent a transplant at the MD Anderson Cancer Center for acute myeloid leukemia AML or myelodysplastic syndrome with TP53 mutations over a 10-year period. https://t.co/zLbgeLyntR #transplantation
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Mashup Score: 4On the road to improved therapies for therapy-related AML - 3 day(s) ago
In this issue of Blood Advances, Sendker et al1 report on a retrospective cohort of pediatric patients with therapy-related acute myeloid leukemia (tAML),
Source: ashpublications.orgCategories: General Medicine NewsTweet-
This article outlines the clinical trials that were conducted during this time frame. https://t.co/q5MTFbS9zE #healthservicesandoutcomes #myeloidneoplasia https://t.co/ArDjokUQBk
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Mashup Score: 8Acute obstetric coagulopathy: need for innovation - 3 day(s) ago
Previously, Collins et al identified distinct coagulopathic changes in a subset of women with severe postpartum hemorrhage (PPH; defined by blood loss >
Source: ashpublications.orgCategories: General Medicine NewsTweet-
To date, little thought has been given to what extent features of obstetric coagulopathy may emulate or differ from TIC or disseminated intravascular coagulation or whether obstetric coagulopathy may be its own entity altogether. https://t.co/F8nAZkzSzC #vascularbiology
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Mashup Score: 2DBA syndrome 2.0: Rpl11 mouse model revisited - 3 day(s) ago
In this issue of Blood Advances, Liu et al present a new mouse model of Diamond-Blackfan anemia (DBA) syndrome (see figure panel A).1 They use a poly I:C-i
Source: ashpublications.orgCategories: General Medicine NewsTweet-
They use a poly I:C-inducible Mx1-Cre system to generate heterozygous Rpl11 knockout mice, employing a previously established mouse model where loxP sites flank exons 3 and 4 of the Rpl11 gene. https://t.co/ieJFtyJvRI #hematopoiesisandstemcells #redcellsironanderythropoiesis https://t.co/RzqO8M97nW
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Mashup Score: 14Long-term outcomes and quality of life with treosulfan-based conditioning in hematological malignancies - 4 day(s) ago
TO THE EDITOR:
Source: ashpublications.orgCategories: General Medicine NewsTweet-
This is a retrospective study of all patients who underwent HCT following Treo-based conditioning at the Fred Hutchinson Cancer Center between 2005 and 2019. https://t.co/ZMJXb9sNzB #transplantation https://t.co/yVuaY2gxYn
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Mashup Score: 9A novel mouse model to study the effects of new therapies for Diamond-Blackfan anemia - 4 day(s) ago
TO THE EDITOR:
Source: ashpublications.orgCategories: General Medicine NewsTweet-
Diamond-Blackfan anemia is an inherited bone marrow failure characterized by macrocytic anemia, congenital malformations, and an increased predisposition to cancer. https://t.co/F40sa9LPLt #redcellsironanderythropoiesis https://t.co/y5RDlHCeZe
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Mashup Score: 20
Blood Advances | 9 | 11 | June 2025
Source: ashpublications.orgCategories: General Medicine NewsTweet-
New Blood Advances issue out now featuring: Characteristics and outcomes of patients with double refractory and double exposed chronic lymphocytic leukemia https://t.co/lDnj73OKYH https://t.co/INvI8qVlnd
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Mashup Score: 28Phase 2 trial of cyclosporine-A, mycophenolate mofetil, and tocilizumab GVHD prophylaxis in cord blood transplantation - 7 day(s) ago
Key PointsTocilizumab was associated with decreased pre-engraftment syndrome, delayed myeloid recovery, and a nonsignificant reduction in aGVHD.The use of
Source: ashpublications.orgCategories: General Medicine NewsTweet-
Tocilizumab was associated with decreased pre-engraftment syndrome, delayed myeloid recovery, and a nonsignificant reduction in aGVHD. https://t.co/jUTM8izItY #transplantation #clinicaltrialsandobservations https://t.co/1GWz8JWJED
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Crizanlizumab and voxelotor were several of the first drugs to receive the US Food and Drug Administration approval for sickle cell disease since the approval of hydroxyurea in 1998. https://t.co/9cN0NT0gdb #healthservicesandoutcomes #redcellsironanderythropoiesis