Regional nodal irradiation (RNI) is increasingly utilized in place of axillary lymph node dissection (ALND) in carefully selected breast cancer patients. While hypofractioned whole breast irradiation is standard for node-negative disease, long-term data on hypofractionated regional nodal irradiation (HF-RNI) are limited. This study aims to assess the long-term safety and effectiveness of HF-RNI for breast cancer patients.

An international workshop was convened by the Reirradiation Collaborative Group (ReCOG). We conducted a survey among the invited attendants to assess practice patterns of reirradiation for central nervous system (CNS) tumors.

The majority of breast cancer patients are treated with breast-conserving surgery followed by postoperative whole (WBI) or partial breast irradiation (PBI). Previous studies on PBI demonstrated similar ipsilateral breast tumor recurrences (IBTR) compared to WBI, however conflicting data on toxicity and cosmetic outcomes were reported. This study investigates the feasibility of stereotactic MRI-guided adaptive radiotherapy (SMART) for PBI, with emphasis on toxicity and cosmetic outcomes.

Prostate cancer is the second most common malignancy diagnosed in men worldwide.1 Conventional imaging used in the staging and management of prostate cancer includes CT, MRI, and bone scan. Advanced imaging modalities including positron emission tomography (PET) scans have potential advantages over conventional imaging, as they measure tumor activity on a molecular level. Prostate-specific membrane antigen (PSMA), a type II transmembrane protein, is overexpressed in prostate cancer cells, making it a viable target for imaging.