In the U.S., incidence rates of some cancers have increased in 15- to 49-year-olds with concomitant increases in older age groups, suggesting that changes in risk factor prevalence and/or improvements in detection could impact risk across age ranges.
Cancer-associated neurons can transfer their mitochondria to cancer cells, boosting their metabolism and function. Mitochondria might also serve as a measure of risk of metastases.…
The FDA’s Oncologic Drugs Advisory Committee (ODAC) recommended against approving belantamab mafodotin (Blenrep; GSK), an antibody–drug conjugate (ADC) for multiple myeloma, due to concerns over…
RAS inhibition reveals how RAS mutations dictate oncogenic signaling and response to therapy, suggests codon-specific treatments against multiple cancers, and explains the high frequency of…
Transition from normal lung to LUAD precursors (by Zhu et al. via Cancer Cell)A new study examined how tumor microenvironment regulated early lung carcinogenesis. By…
Ahead of tomorrow’s meeting of the FDA’s Oncologic Drugs Advisory Committee, agency reviewers published a document that flags ocular toxicity from belantamab mafodotin (Blenrep; GSK),…
The Department of Health and Human Services (DHHS) proceeded with firing thousands of employees yesterday afternoon following a Supreme Court decision allowing it to do…
Single-cell analyses of a spontaneous glioblastoma mouse model and tumor-free subventricular zone tissues from patients identify precancerous cells, arising via an oligodendrocyte progenitor lineage, that…
AbstractTo explore how early cancers can be detected prior to clinical signs or symptoms, we assessed prospectively collected serial plasma samples from the Atherosclerosis Risk…
Cancer Prevention Research | 18 | 7 | July 2025
Abstract. Introduction: Many patients have residual disease after neoadjuvant therapy but their prognosis and need for adjuvant therapy is unclear. This study evaluates patient prognosis…
