The scientific events that shaped the decade
The 2010s have seen breakthroughs in frontiers from gene editing to gravitational waves. The coming one must focus on climate change.
The 2010s have seen breakthroughs in frontiers from gene editing to gravitational waves. The coming one must focus on climate change.
Nature Biotechnology – A barcoded CRISPR base editing system isolates target clones from complex mammalian, yeast and bacterial populations.
Nature Reviews Microbiology – In this Review, Fouchier and colleagues explore the evolution, spread and zoonotic risks of highly pathogenic H5 avian influenza viruses. They…
Nature – Following spinal cord injury, gamified physical therapy that incorporates closed-loop vagus nerve stimulation can aid restoration of arm and hand function.
Eye – Stereopsis in the Infant Aphakia Treatment Study: outcome at 10½ years
Communications Psychology – Six Large Language Models outperformed humans on five ability emotional intelligence tests. ChatGPT-4 also successfully generated new test items for each test,…
Molecular Psychiatry – Effects of KCNQ potassium channel modulation on ventral tegmental area activity and connectivity in individuals with depression and anhedonia
Nature – The discovery that DNA methylation of different CpG sites can serve as digital barcodes of clonal identity led to the development of EPI-Clone,…
Nature Reviews Neurology – In this Review, Taddei and Duff consider the concepts of synapse vulnerability and resilience, and how an understanding of the mechanisms…
Nature – PCSK9 regulates low density lipoprotein-cholesterol import and determines organ preference of metastatic pancreatic ductal adenocarcinoma, with PCSK9-low cells metastasizing to the liver…
Nature Neuroscience – White matter aging leads to degenerative and inflammatory changes. Here the authors show that microglial dysfunction exacerbates glial CXCL10 expression, harmful CD8+…