The oesophagus as an immune organ
Nature Reviews Gastroenterology & Hepatology – This Perspective article provides a detailed overview of the oesophagus as an immune organ, highlighting its innate immune components and sensing…
Nature Reviews Gastroenterology & Hepatology – This Perspective article provides a detailed overview of the oesophagus as an immune organ, highlighting its innate immune components and sensing…
Nature Communications – The immune response to tumour development is frequently targeted with therapeutics but remains largely unexplored in diagnostics. Here this groups designs an…
Post written by Benjamin Norton, MD, from Cleveland Clinic London, London, United Kingdom. We are currently experiencing an obesity and diabetic epidemic. We know that…
Nature Biotechnology – As governments around the world begin to embrace artificial intelligence in healthcare, clinical trials are entering a new phase — faster, smarter…
Background Gut microbial metabolites are recognised as critical effector molecules that influence the development of colorectal cancer (CRC). Peptidoglycan fragments (PGFs) produced by microbiota play…
To cite: Guisado D, Talware S, Wang X, et al. Reparative immunological consequences of stem cell transplantation as a cellular therapy for refractory Crohn’s…
Immune checkpoint inhibitors (ICI) have led to breakthrough improvements in the management of malignancy including hepatocellular (HCC) and biliary tract cancer, improving decades-old standards of…
Background Tumour-infiltrating T cells can mediate both antitumour immunity and promote tumour progression by creating an immunosuppressive environment. This dual role is especially relevant in…
Background and aims Quantifying systemic inflammation (SI) in acutely decompensated cirrhosis (ADC) is of major importance because SI is a driver of the most severe…
Nature Neuroscience – The hippocampus and insula communicate when processing emotional memories. Discrete sites in the human insular cortex showed changes that predicted later memory…
Translational Psychiatry – Association of viral RNAs in the choroid plexus with bipolar disorder and schizophrenia and evidence for the hepatitis C virus involvement in…