The Lancet Haematology, January 2020, Volume 7, Issue 1, Pages e1-e81
Explore the current issue of The Lancet Haematology, a monthly journal dedicated to publishing content that advocates change in, or illuminates, haematological clinical practice
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Type 2 diabetes and accelerated ageing in skeletal muscle
The pursuit for the elixir of eternal youth has fascinated scientists for centuries. Yet, natural ageing—marked by the gradual decline of biological, physiological, psychological, and…
Association between maternal diabetes and neurodevelopmental outcomes in children: a systematic review and meta-analysis of 202 observational studies comprising 56·1 million pregnancies
Maternal diabetes is associated with an increased risk of neurodevelopmental disorders and impaired neurodevelopmental performance in children. Further high-quality research is needed to establish causality…
Continuous glucose monitoring in the management of gestational diabetes in Switzerland (DipGluMo): an open-label, single-centre, randomised, controlled trial
Our results show that the outcome in individuals with gestational diabetes is not improved by the use of rtCGM. However, individuals expressed a higher preference…
Polymyalgia rheumatica: killing them softly
Polymyalgia rheumatica has long been neglected, especially when it comes to pharmaceutical development: but why? In 2025, polymyalgia rheumatica should have a broad therapeutic armamentarium…
Sarilumab in relapsing polymyalgia rheumatica: patient-reported outcomes from a phase 3, double-blind, randomised controlled trial
Patients with relapsing polymyalgia rheumatica have impaired health-related quality of life. The use of sarilumab 200 mg once every 2 weeks with a 14-week glucocorticoid…
The 2025 Wakley Prize: changing practice
Life, as philosopher Søren Kierkegaard put it, “must be understood backwards; but…it must be lived forwards”.1 Clinical experiences are often only fully understood in retrospect;…
Predictors of treatment-emergent resistance to dolutegravir
Integrase strand transfer inhibitor (INSTI)-based regimens became a first-line treatment for HIV worldwide in 2018, with 93% of people with HIV who are on antiretroviral…
The mpox response: African leadership, global responsibility
On June 9, WHO Director-General Tedros Adhanom Ghebreyesus announced that mpox would remain a public health emergency of international concern (PHEIC)—the highest level of alarm…
First results from the international paediatric bronchiectasis registry (Child-BEAR-Net Registry) describing multicountry variations in childhood bronchiectasis and its management: a multicentre, cross-sectional study
Our study presents the first internationally derived paediatric registry data highlighting geographical variations in cause, lung function, bacteriology, and treatment in children and young people…
First-in-world Trojan horse drug offered to multiple myeloma patients in England
On June 13, 2025, the UK National Institute for Health and Care Excellence (NICE) issued draft guidance recommending the use of belantamab mafodotin as a…
