In this post-hoc analysis, compared with placebo, canagliflozin reduced serum urate concentration and also reduced events related to gout flare among patients with type 2 diabetes. A trial explicitly designed to test the effects of sodium glucose co-transporter 2 inhibition on gout is required to confirm these observations.
Edoardo Cipolletta and colleagues1 present compelling evidence that colchicine flare prophylaxis reduces cardiovascular event risk within 180 days of initiating urate-lowering therapy in patients with…
Aberrant B-cell function, which could arise from various underlying causes, is central to the pathogenesis of diverse autoimmune rheumatic diseases. B cells remain the only…
Dazukibart, a humanised monoclonal antibody targeting interferon (IFN) β, might be safe and effective for patients with dermatomyositis, according to a phase 2, double-blind trial…
We read the Article by Sebastian E Sattui and colleagues1 with interest. The authors show that in patients aged 65 years or older with antineutrophil…
We provide the first evidence that CD19-targeting CAR T-cell therapy might intercept with the progression of fibrotic organ manifestations in patients with systemic sclerosis.
Editors at The Lancet Rheumatology, in conversation with the journal’s authors, explore their latest research and its impact on people’s health, healthcare, and health policy.A…
The recommendations from this study will inform the development of arthritis educational resources for Aboriginal Peoples. The findings can also support health professionals to deliver…
Dr Brooke Conley and Associate Professor Ivan Lin discuss their recent study on integrating evidence from lived experience of Aboriginal people and clinical practice guidelines…
Despite improvement in pain and function in both groups, adding moderate-intensity aerobic physical activity to resistance exercise did not lead to superior outcomes. Future work…
Despite improvement in pain and function in both groups, adding moderate-intensity aerobic physical activity to resistance exercise did not lead to superior outcomes. Future work…
