The Cancer News Daily
The latest in cancer medicine and translational research by Wafik El-Deiry MDPhD
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Former WBZ anchor Kate Merrill sues station, network for $4 million, alleging racial and gender discrimination – The Boston Globe
Merrill, who abruptly left WBZ in 2024, claims the Boston station and two companies took a “career-ending action” against her to “advance a DEI agenda,”…
Massively parallel immunopeptidome by DNA sequencing provides insights into cancer antigen presentation
Nature Genetics – ESCAPE-seq (enhanced single-chain antigen presentation sequencing) is a massively parallel platform for screening of class I HLA–peptide combinations for antigen…
Circulating Tumor Cells Shed Shearosome Extracellular Vesicles in Capillary Bifurcations That Activate Endothelial and Immune Cells
Using microfluidic models of capillary networks, this study discovered that fluid shear stresses on circulating tumor cells transiting through capillary-sized bifurcations shed a novel class…
Cellular ‘trash bins’ might be a key to reviving multi-cancer early detection tests
Researchers are turning to a new approach for early cancer detection, making use of nanoscale biological structures called extracellular vesicles.
Dana-Farber and Brigham may be breaking up, but for now they’re still one of the country’s best cancer hospitals – The Boston Globe
US News rankings highlight the scrum between Dana-Farber and Mass General Brigham over cancer care in Greater Boston.
Mitochondria-derived nuclear ATP surge protects against confinement-induced proliferation defects
Nature Communications – The authors uncover a mechano-metabolic adaptation where confinement induces rapid mitochondrial relocalization to the nuclear periphery, generating localized nuclear ATP…
The #LegorretaCancerCenter at Brown University The Warren Alpert Medical School of Brown University is very grateful to Sheldon Holder for the impact he has had in the Community in Rhode Island over… | Wafik S. El-Deiry, MD, PhD, FACP
The #LegorretaCancerCenter at Brown University The Warren Alpert Medical School of Brown University is very grateful to Sheldon Holder for the impact he has had…
AI is dangerously spreading misinformation
Cautionary note about AI involvement in science, medicine and public availability without accountability
A STAT3/integrin axis accelerates pancreatic cancer initiation and progression
Campos and Shepard et al. report that hypoxia and inflammatory cytokines activate the STAT3/integrin β3 axis, promoting stress tolerance and accelerating pancreatic cancer initiation and…
Medical group urges Kennedy not to fire US care task force
U.S. Health Secretary Robert F. Kennedy Jr. should not fire an advisory panel that determines what cancer screenings and other preventive health measures insurers must…