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A significant proportion of patients with severe aortic stenosis (AS) undergoing transcatheter aortic valve implantation (TAVI) have concomitant coronary artery disease (CAD). The best way…
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Background Cardiac sarcoidosis (CS) is a chronic inflammatory disease characterised by non-caseating granulomas, while arrhythmogenic cardiomyopathy (ACM) is a genetic condition mainly affecting desmosomal proteins.…
Blood pressure management in type 2 diabetes: a review of recent evidence | Heart Podcast
In this episode of the Heart podcast, Digital Media Editor, Professor James Rudd, is joined by Professor Kazem Rahimi from the University of Oxford. They…
Mechanical circulatory support for patients with infarct-related cardiogenic shock: a state-of-the-art review
Acute myocardial infarction-related cardiogenic shock (AMI-CS) is a severe, life-threatening condition characterised by inadequate tissue perfusion due to the heart’s inability to pump blood effectively.…
Evolving use and clinical outcomes of coronary intravascular lithotripsy: insights from an international, multicentre registry
Background Intravascular lithotripsy (IVL) is increasingly used for treatment of coronary artery calcification. This study aimed to evaluate contemporary utilisation patterns, safety and efficacy of…
Transitioning to high-sensitivity troponin: 1-year mortality outcomes in patients with suspected acute coronary syndrome presenting to emergency departments
Background Switching from a conventional to a high-sensitivity cardiac troponin (hs-cTn) assay enables detection of smaller amounts of myocardial damage, but the clinical benefit is…
Heart failure in low-income and middle-income countries
Heart failure (HF) is a complex syndrome which leads to significant morbidity and mortality, poor quality of life and extremely high costs to healthcare systems…
Prognostic impact of albuminuria in early-stage chronic kidney disease on cardiovascular outcomes: a cohort study
Background The impact of early-stage chronic kidney disease (CKD) on cardiovascular outcomes, particularly when albuminuria is present, remains unclear. This study examined the associations between…
Industry marketing payments to physicians and prescription patterns for sacubitril/valsartan in the USA
Objectives Although financial interactions between physicians and pharmaceutical and medical device companies could be potential conflicts of interest, in certain instances, industry promotion targeted at…