Targeting PGM3 abolishes SREBP-1 activation-hexosamine synthesis feedback regulation to effectively suppress brain tumor growth
Hexosamine synthesis pathway and SCAP/SREBP-1 reciprocally enhance each other to drive malignant brain tumor growth.
Hexosamine synthesis pathway and SCAP/SREBP-1 reciprocally enhance each other to drive malignant brain tumor growth.
Intense mechanization is efficient, but may crush the root zone and lessen harvests
A big-budget flop about terraforming Mars had a ground-aerial robot team predating Perseverance and Ingenuity.
Repeated ketamine treatment to maintain a rapid antidepressant effect can lead to side effects over time, highlighting an unmet clinical need for sustaining this drug’s…
On-demand dental-floss-based point-of-care platform is developed for the noninvasive and real-time quantification of salivary cortisol utilizing redox-molecule embedded molecularly imprinted polymer structures and thread microfluidics.…
Drug combination targeting lax airways is nearing an FDA submission
Drug combination targeting lax airways is nearing an FDA submission
Dysregulated T cells and progenitors with lymphoma driver mutations are enriched in duodenal biopsies from patients with refractory celiac disease.
New metric identifying “persistently disruptive” papers offers a “bright spot” amid signs of declining innovation
Closing of programs that fought neglected diseases imperils drug donation and distribution efforts in 26 countries
Long noncoding RNA PRCAT71 and RNA binding protein KHSRP stabilize androgen receptor mRNA to promote prostate cancer progression.