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Mashup Score: 0Cystic fibrosis triple therapy does not eliminate bacterial infection predisposal in vitro - 1 year(s) ago
It is known that persons with cystic fibrosis are more susceptible to infections; however, the impact of elexacaftor/tezacaftor/ivacaftor therapy on this susceptibility has not been well studied yet. In a study published in American Journal of Respiratory Cell and Molecular Biology, researchers explored whether triple therapy stopped docking stations, a mechanism tied to bacterial infections,
Source: www.healio.comCategories: General Medicine News, PulmonologyTweet
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Mashup Score: 0Cystic fibrosis triple therapy does not eliminate bacterial infection predisposal in vitro - 1 year(s) ago
It is known that persons with cystic fibrosis are more susceptible to infections; however, the impact of elexacaftor/tezacaftor/ivacaftor therapy on this susceptibility has not been well studied yet. In a study published in American Journal of Respiratory Cell and Molecular Biology, researchers explored whether triple therapy stopped docking stations, a mechanism tied to bacterial infections,
Source: www.healio.comCategories: General Medicine News, PulmonologyTweet-
Researchers explored whether triple therapy stopped docking stations, a mechanism tied to bacterial #infections, from forming in those with cystic fibrosis. @AJRCMB Healio spoke with Marc Chanson, PhD, and Mehdi Badaoui, PhD, @UNIGEnews, to learn more🔽 https://t.co/0hMo0vQyGJ
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Mashup Score: 1
Acta Pharmacologica Sinica – Ripretinib inhibits HIV-1 transcription through modulation of PI3K-AKT-mTOR
Source: www.nature.comCategories: General Medicine News, Infectious DiseaseTweet-
Researchers discovered ripretinib being an LPA candidate, which was ✔️ validated and observed to hinder proviral activation in cell models harboring latent #infections, as well as CD4+ T cells 🧫 derived from infected patients. 🔗 https://t.co/mNsqc4MnM1 https://t.co/2KDB0rf6oc
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Mashup Score: 1
The U.K. Medicines and Healthcare products Regulatory Agency recently approved a phase 1 study that will test an inhaled mRNA-based drug as a treatment and prophylaxis of respiratory viral infections, according to a press release.In this trial, healthy participants will receive ETH47 (Ethris) through inhalation or nasal spray.
Source: www.healio.comCategories: General Medicine News, PulmonologyTweet-
An inhaled mRNA-based drug, ETH47 (Ethris), will be tested as a treatment and prophylaxis for respiratory viral #infections🤧, and Healio spoke with Carsten Rudolph, PhD, CEO of @ethris_mRNA, to learn more. Read more⬇️ https://t.co/LoimgemWZa
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Mashup Score: 1
The U.K. Medicines and Healthcare products Regulatory Agency recently approved a phase 1 study that will test an inhaled mRNA-based drug as a treatment and prophylaxis of respiratory viral infections, according to a press release.In this trial, healthy participants will receive ETH47 (Ethris) through inhalation or nasal spray.
Source: www.healio.comCategories: General Medicine News, PulmonologyTweet-
An inhaled mRNA-based drug, ETH47 (Ethris), will be tested as a treatment and prophylaxis for respiratory viral #infections🤧, and Healio spoke with Carsten Rudolph, PhD, CEO of @ethris_mRNA, to learn more. Read more⬇️ https://t.co/LoimgemWZa
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Mashup Score: 6Source: link.springer.comCategories: Latest Headlines, RheumatologyTweet
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📌Patients with #ANCAvasculitis are prone to invasive #fungal #infections (IFI) due to immunosuppression, tissue necrosis, and iron availability in the necrotic tissues 📌Differentiating disease activity from IFI is difficult 📌Poor prognosis 👉https://t.co/JCPicJbQu7 https://t.co/tzF0SjOGL7
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Mashup Score: 1MyD88 signaling by neurons induces chemokines that recruit protective leukocytes to the virus-infected CNS - 2 year(s) ago
During viral CNS infection, MyD88 signaling in infected neurons orchestrates recruitment of protective peripheral immune cells.
Source: www.science.orgCategories: Allergy-Immunology, Latest HeadlinesTweet-
A 2021 study from @stanfordimmuno @VAPaloAlto in mice and human #Tcells yielded a better understanding of why older individuals have a harder time fighting off #infections and provided a potential target for anti-aging treatments. 📄: https://t.co/m22Rs2DaoO #WeekendReads https://t.co/gIKqvFMboz
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Mashup Score: 0Infections, Rather Than Inflammation or Autoimmune Disease, Associated With Dementia Development - 2 year(s) ago
A nationwide study conducted in Denmark found an association between dementia incidence and previous exposure to infection, but the potential impacts of systemic inflammation or autoimmune diseases on dementia incidence were not as clear.
Source: www.ajmc.comCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
Intriguing connections between #dementia incidence and prior exposure to #infections were revealed according to a study from Denmark. However, the influence of #SystemicInflammation or #AutoimmuneDiseases on #dementia incidence remained complex. https://t.co/iFnoCAUXNK https://t.co/b1vMamHS9p
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Mashup Score: 0
Campylobacter infection usually causes a self-limited clinical illness lasting 5 to 7 days, resolving without antimicrobial treatment in immunocompetent subjects. However, an inadequate immune response can lead to a prolonged and severe disease requiring antibiotics and more aggressive therapeutic approaches.
Source: www.jaci-inpractice.orgCategories: Allergy-Immunology, Latest HeadlinesTweet-
In Press! #Clinical Features, #Immunological Characteristics, and #Treatment #Outcomes of #Campylobacter spp. #Infections in #Patients With Common #Variable #Immunodeficiency https://t.co/P0gSBdUDog https://t.co/GfE6a5Azuv
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Mashup Score: 0Mortality in Culture-Negative Sepsis Not Linked to Early Discontinuation of Antibiotics - 2 year(s) ago
Early discontinuation of antibiotics was not significantly associated with increased mortality risk among patients with culture-negative severe sepsis.
Source: Infectious Disease AdvisorCategories: Infectious Disease, Latest HeadlinesTweet-
Early discontinuation of #antibiotics among patients with culture-negative severe #infections and sepsis is not associated with increased risk of #mortality, according to study results. https://t.co/dsUtP5mdnc
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Researchers explored whether triple therapy stopped docking stations, a mechanism tied to bacterial #infections, from forming in those with cystic fibrosis. @AJRCMB Healio spoke with Marc Chanson, PhD, and Mehdi Badaoui, PhD, @UNIGEnews, to learn more🔽 https://t.co/0hMo0vQyGJ