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Mashup Score: 12Surgeons' choice of skin disinfectant impacts infection risk, Canadian-American study shows - 1 year(s) ago
Does the type of solution used by surgeons to disinfect skin before surgery impact the risk of surgical site infection? According to new research from an international trial jointly led by McMaster University …
Source: medicalxpress.comCategories: General Medicine News, General NewsTweet
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Mashup Score: 50
Background The neurological effects of the coronavirus disease of 2019 (COVID-19) raise concerns about potential long-term consequences, such as an increased risk of Alzheimer’s disease (AD). Neuroinflammation and other AD-associated pathologies are also suggested to increase the risk of serious SARS-CoV-2 infection. Anosmia is a common neurological symptom reported in COVID-19 and in early AD. The olfactory mucosa (OM) is important for the perception of smell and a proposed site of viral entry to the brain. However, little is known about SARS-CoV-2 infection at the OM of individuals with AD. Methods To address this gap, we established a 3D in vitro model of the OM from primary cells derived from cognitively healthy and AD individuals. We cultured the cells at the air–liquid interface (ALI) to study SARS-CoV-2 infection under controlled experimental conditions. Primary OM cells in ALI expressed angiotensin-converting enzyme 2 (ACE-2), neuropilin-1 (NRP-1), and several other known SARS-
Categories: General Medicine News, General NewsTweet-
Study shows COVID-19 #infection alters gene transcription of olfactory mucosal cells in Alzheimer's disease https://t.co/vXgg3biV8E https://t.co/Yv1fG4MGQ6
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Mashup Score: 50
Background The neurological effects of the coronavirus disease of 2019 (COVID-19) raise concerns about potential long-term consequences, such as an increased risk of Alzheimer’s disease (AD). Neuroinflammation and other AD-associated pathologies are also suggested to increase the risk of serious SARS-CoV-2 infection. Anosmia is a common neurological symptom reported in COVID-19 and in early AD. The olfactory mucosa (OM) is important for the perception of smell and a proposed site of viral entry to the brain. However, little is known about SARS-CoV-2 infection at the OM of individuals with AD. Methods To address this gap, we established a 3D in vitro model of the OM from primary cells derived from cognitively healthy and AD individuals. We cultured the cells at the air–liquid interface (ALI) to study SARS-CoV-2 infection under controlled experimental conditions. Primary OM cells in ALI expressed angiotensin-converting enzyme 2 (ACE-2), neuropilin-1 (NRP-1), and several other known SARS-
Categories: General Medicine News, General NewsTweet-
Study shows COVID-19 #infection alters gene transcription of olfactory mucosal cells in Alzheimer's disease https://t.co/vXgg3biV8E https://t.co/Yv1fG4MGQ6
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Mashup Score: 7Silver─Gallium Nano‐Amalgamated Particles as a Novel, Biocompatible Solution for Antibacterial Coatings - 2 year(s) ago
Advanced Functional Materials, part of the prestigious Advanced portfolio and a top-tier materials science journal, publishes outstanding research across the field.
Source: onlinelibrary.wiley.comCategories: General Medicine News, General NewsTweet-
New implants could reduce #infection and lead to better recovery from orthopedic surgery @flinders https://t.co/fZku2Qd4cc https://t.co/5IayVOjKRl
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Mashup Score: 9Long-term neurological and neurodevelopmental outcome of neonatal listeriosis in France: a prospective, matched, observational cohort study - 2 year(s) ago
Maternal–neonatal listeriosis is a rare and serious infection. The long-term outcome of surviving infants with early-onset or late-onset listeriosis r…
Source: www.sciencedirect.comCategories: General Medicine News, General NewsTweet-
Study finds long-term outcomes of neonatal listeriosis are mainly due to prematurity rather than #infection @institutpasteur https://t.co/EB0IzSppac https://t.co/OgNdDf9qgN
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Mashup Score: 8
MXRA8 is a receptor for chikungunya (CHIKV) and other arthritogenic alphaviruses with mammalian hosts. However, mammalian MXRA8 does not bind to alpha…
Source: www.sciencedirect.comCategories: General Medicine News, General HCPsTweet-
Researchers identify way to block alphavirus #infection @wustl @CellCellPress https://t.co/1FST6hNWhj https://t.co/OLZ41KH4o9
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Mashup Score: 13
Nature – Stress granules function at sites of intracellular membrane damage by forming on and stabilizing the ruptured membrane and promoting membrane repair.
Source: www.nature.comCategories: General Medicine News, General NewsTweet-
Researchers uncover role of 'molecular plasters' that protect against #infection @thecrick https://t.co/HGLC0srs5P https://t.co/l4M5M2lYsq
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Mashup Score: 2mAb therapy controls CNS‐resident lyssavirus infection via a CD4 T cell‐dependent mechanism - 2 year(s) ago
Rabies is a fatal viral disease of humans, with uniform mortality once central nervous system (CNS) invasion occurs and symptoms appear. This study demonstrates that a single-dose monoclonal (mAb) th…
Source: www.embopress.orgCategories: Infectious Disease, Latest HeadlinesTweet-
This study out of @USUhealthsci shows that a single dose of F11, an anti-lyssavirus human monoclonal #antibody, limited viral load in the 🧠 brain and reversed disease signs following #infection with a lethal dose of #lyssavirus! @EmboMolMed | https://t.co/xdo3th54zX https://t.co/f6rT6ojs3J
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Mashup Score: 3
This single-day virtual course brings you up to speed on current knowledge in periprosthetic infection following total hip and total knee arthroplasty. Through insights shared in dynamic lectures, interactive Q&A sessions, and challenging case discussions, you will evaluate diagnostic dilemmas, formulate treatment plans, and gain strategies for medical and social management in the preoperative period.
Source: www.aaos.orgCategories: Latest Headlines, OrthopedicsTweet-
In 10 days, we're kicking off a NEW virtual course focused on #periprosthetic #infection following total #hip and total #knee #arthroplasty, presented by AAOS, @MSISorg and ICMI. View the course schedule and register: https://t.co/7irEZBpUMv #OrthoTwitter #OrthoX https://t.co/8KiUYLzycs
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Mashup Score: 0Epithelial plasticity and innate immune activation promote lung tissue remodeling following respiratory viral infection - 2 year(s) ago
Nature Communications – After respiratory viral infection and in fibrotic lung disease, repair and remodeling processes particularly affect airway basal cell (BC) and alveolar epithelial cell…
Source: www.nature.comCategories: Infectious Disease, Latest HeadlinesTweet-
🔬 Dr. Barry Stripp and researchers at @CedarsSinaiMed showed that a subset of distal #airway secretory cells, intralobar serous cells, were ✔️ activated to assume basal cell fates following #influenza virus #infection. 📖 @naturecomms | https://t.co/FLrd8EIoRH https://t.co/Vy7JiLLT2w
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Surgeons' choice of skin disinfectant impacts #infection risk, Canadian-American study shows @mcmastereng @nejm https://t.co/xK3FdegFpu